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TNNI2 elisa kit :: Porcine TNNI2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2514548 TNNI2 elisa kit
Unit / Price
48-Strip-Wells  /  $450 +1 FREE 8GB USB
96-Strip-Wells  /  $535 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,255 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


★Popular Item★
 Also Known As   

Porcine TNNI2 (Troponin I Type 2, Fast Skeletal) ELISA Kit

 Product Gene Name   

TNNI2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2514548 COA    COA PDF
 OMIM    191043
 3D Structure    ModBase 3D Structure for P48788
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 Species Reactivity    Porcine
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 Specificity    This kit recognizes natural and recombinant Porcine TNNI2. No significant cross-reactivity or interference between Porcine TNNI2 and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    78.125-5000pg/mL
 Sensitivity    Min: 46.875pg/mL; Max: 5000pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TNNI2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TNNI2 purchase    MBS2514548 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the TNNI2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 78.125-5000pg/mL in biological research samples containing TNNI2, with an estimated sensitivity of Min: 46.875pg/mL; Max: 5000pg/mL. The ELISA analytical biochemical technique of the MBS2514548 kit is based on TNNI2 antibody-TNNI2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TNNI2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TNNI2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for TNNI2 elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Porcine TNNI2 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to TNNI2. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for TNNI2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain TNNI2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of TNNI2. You can calculate the concentration of TNNI2 in the samples by comparing the OD of the samples to the standard curve.
Sample Manual Insert of MBS2514548. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TNNI2. It may not necessarily be applicable to this product.
 NCBI GI #    224967106
 NCBI GeneID    7136
 NCBI Accession #    NP_001139313.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001145841.1 [Other Products]
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 UniProt Primary Accession #    P48788 [Other Products]
 UniProt Secondary Accession #    A6NIV8; A6NJU5 [Other Products]
 UniProt Related Accession #    P48788 [Other Products]
 Molecular Weight    21,355 Da
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 NCBI Official Full Name    troponin I, fast skeletal muscle isoform 2
 NCBI Official Synonym Full Names    troponin I type 2 (skeletal, fast)
 NCBI Official Symbol    TNNI2 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    troponin I, fast skeletal muscle; troponin I fast twitch 2; troponin I, fast-twitch isoform; troponin I, fast-twitch skeletal muscle isoform; troponin I, skeletal, fast
 UniProt Protein Name    Troponin I, fast skeletal muscle
 UniProt Synonym Protein Names   
Troponin I, fast-twitch isoform
 Protein Family    Troponin
 UniProt Gene Name    TNNI2 [Similar Products]
 UniProt Entry Name    TNNI2_HUMAN
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 NCBI Summary for TNNI2    This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
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 UniProt Comments for TNNI2    TNNI2: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Defects in TNNI2 are a cause of distal arthrogryposis type 2B (DA2B); also known as arthrogryposis multiplex congenita, distal, type 2B (AMCD2B). DA2B is a form of inherited multiple congenital contractures. Affected individuals have vertical talus, ulnar deviation in the hands, severe camptodactyly, and a distinctive face characterized by a triangular shape, prominent nasolabial folds, small mouth and a prominent chin. Belongs to the troponin I family.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: troponin complex; cytosol; nucleus

Molecular Function: troponin T binding; protein binding; actin binding

Biological Process: skeletal muscle contraction; regulation of muscle contraction; positive regulation of transcription, DNA-dependent; muscle filament sliding

Disease: Arthrogryposis, Distal, Type 2b
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 Research Articles on TNNI2    1. report the first TNNI2 mutation in classical FSS and describe an atypical adult FSS case with only facial contractures resulting from somatic mosaicism
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TNNI2 elisa kitPathways associated with TNNI2 elisa kit
 Reference Product  PubMed Publications
 TPM2 elisa kit  >14 publications with TNNI2 and TPM2
 TNNT3 elisa kit  >14 publications with TNNI2 and TNNT3
 MYH3 elisa kit  >9 publications with TNNI2 and MYH3
 TNNT1 elisa kit  >3 publications with TNNI2 and TNNT1
 TNNC2 elisa kit  >3 publications with TNNI2 and TNNC2
 TPM1 elisa kit  >2 publications with TNNI2 and TPM1
 TNNC1 elisa kit  >1 publications with TNNI2 and TNNC1
 MYL1 elisa kit  >1 publications with TNNI2 and MYL1
 TNNT2 elisa kit  >1 publications with TNNI2 and TNNT2
 Products by Pathway  Pathway Diagram
 Muscle Contraction Pathway antibodies  Muscle Contraction Pathway Diagram
 Striated Muscle Contraction Pathway antibodies  Striated Muscle Contraction Pathway Diagram
 Striated Muscle Contraction Pathway antibodies  Striated Muscle Contraction Pathway Diagram
Diseases associated with TNNI2 elisa kitOrgans/Tissues associated with TNNI2 elisa kit
 Disease Name  Pubmed Publications
 Muscular Diseases Antibodies  >17 publications with TNNI2 and Muscular Diseases
 Distal arthrogryposis type 2B Antibodies  >6 publications with TNNI2 and Distal arthrogryposis type 2B
 Cardiovascular Diseases Antibodies  >4 publications with TNNI2 and Cardiovascular Diseases
 Heart Diseases Antibodies  >4 publications with TNNI2 and Heart Diseases
 Disease Models, Animal Antibodies  >2 publications with TNNI2 and Disease Models, Animal
 Heart Defects, Congenital Antibodies  >1 publications with TNNI2 and Heart Defects, Congenital
 Cognition Disorders Antibodies  >1 publications with TNNI2 and Cognition Disorders
 Hypertrophy Antibodies  >1 publications with TNNI2 and Hypertrophy
 Kidney Diseases Antibodies  >1 publications with TNNI2 and Kidney Diseases
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with TNNI2 and Prenatal Exposure Delayed Effects
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >31 publications with TNNI2 and Muscle
 Heart Antibodies  >12 publications with TNNI2 and Heart
 Mouth Antibodies  >3 publications with TNNI2 and Mouth
 Connective Tissue Antibodies  >2 publications with TNNI2 and Connective Tissue
 Eye Antibodies  >2 publications with TNNI2 and Eye
 Embryonic Tissue Antibodies  >2 publications with TNNI2 and Embryonic Tissue
 Lung Antibodies  >2 publications with TNNI2 and Lung
 Bone Antibodies  >1 publications with TNNI2 and Bone
 Kidney Antibodies  >1 publications with TNNI2 and Kidney
 Pancreas Antibodies  >1 publications with TNNI2 and Pancreas
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