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PRPF3 elisa kit :: Porcine U4/U6 small nuclear ribonucleoprotein Prp3 (PRPF3) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7212687 PRPF3 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

U4/U6 small nuclear ribonucleoprotein Prp3 (PRPF3), ELISA Kit

 Also Known As   

Porcine U4/U6 small nuclear ribonucleoprotein Prp3 (PRPF3) ELISA Kit

 Product Gene Name   

PRPF3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    607301
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 Species Reactivity    Porcine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PRPF3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PRPF3 purchase    MBS7212687 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the U4/U6 small nuclear ribonucleoprotein Prp3 (PRPF3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PRPF3. The ELISA analytical biochemical technique of the MBS7212687 kit is based on PRPF3 antibody-PRPF3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PRPF3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PRPF3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for PRPF3 elisa kit    Epigenetics and Nuclear Signaling
NCBI/Uniprot data below describe general gene information for PRPF3. It may not necessarily be applicable to this product.
 NCBI GI #    4758556
 NCBI GeneID    9129
 NCBI Accession #    NP_004689.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004698.2 [Other Products]
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 UniProt Secondary Accession #    O43446; Q5VT54 [Other Products]
 UniProt Related Accession #    O43395 [Other Products]
 Molecular Weight    77,529 Da
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 NCBI Official Full Name    U4/U6 small nuclear ribonucleoprotein Prp3
 NCBI Official Synonym Full Names    pre-mRNA processing factor 3
 NCBI Official Symbol    PRPF3 [Similar Products]
 NCBI Official Synonym Symbols   
PRP3; RP18; HPRP3; Prp3p; HPRP3P; SNRNP90
[Similar Products]
 NCBI Protein Information    U4/U6 small nuclear ribonucleoprotein Prp3; U4/U6 snRNP 90 kDa protein; pre-mRNA-splicing factor 3; U4/U6-associated RNA splicing factor; PRP3 pre-mRNA processing factor 3 homolog
 UniProt Protein Name    U4/U6 small nuclear ribonucleoprotein Prp3
 UniProt Synonym Protein Names   
Pre-mRNA-splicing factor 3; hPrp3; U4/U6 snRNP 90 kDa protein
 Protein Family    U4/U6 small nuclear ribonucleoprotein
 UniProt Gene Name    PRPF3 [Similar Products]
 UniProt Synonym Gene Names    HPRP3; PRP3; hPrp3 [Similar Products]
 UniProt Entry Name    PRPF3_HUMAN
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 NCBI Summary for PRPF3    The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. This gene product is one of several proteins that associate with U4 and U6 snRNPs. Mutations in this gene are associated with retinitis pigmentosa-18. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PRPF3    PRPF3: Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex. Defects in PRPF3 are the cause of retinitis pigmentosa type 18 (RP18). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP18 inheritance is autosomal dominant.

Protein type: RNA processing; RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 1q21.1

Cellular Component: nucleoplasm; spliceosome; Cajal body; U4/U6 x U5 tri-snRNP complex; cytoplasm; nuclear speck; nucleus

Molecular Function: identical protein binding; protein binding

Biological Process: RNA splicing, via transesterification reactions; nuclear mRNA splicing, via spliceosome; assembly of spliceosomal tri-snRNP; RNA splicing; mRNA processing

Disease: Retinitis Pigmentosa 18
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 Research Articles on PRPF3    1. RP-PRPF defects affect the stoichiometry of spliceosomal small nuclear RNAs. Mutant PRPF3 proteins stably associated with tri-snRNPs.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PRPF3 elisa kitPathways associated with PRPF3 elisa kit
 Reference Product  PubMed Publications
 SART3 elisa kit  >1 publications with PRPF3 and SART3
 Products by Pathway  Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome, U4/U6.U5 Tri-snRNP Pathway antibodies  Spliceosome, U4/U6.U5 Tri-snRNP Pathway Diagram
 Spliceosome, U4/U6.U5 Tri-snRNP Pathway antibodies  Spliceosome, U4/U6.U5 Tri-snRNP Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram
Diseases associated with PRPF3 elisa kitOrgans/Tissues associated with PRPF3 elisa kit
 Disease Name  Pubmed Publications
 Retinitis Pigmentosa 18 Antibodies  >3 publications with PRPF3 and Retinitis Pigmentosa 18
 Nervous System Diseases Antibodies  >2 publications with PRPF3 and Nervous System Diseases
 Disease Models, Animal Antibodies  >2 publications with PRPF3 and Disease Models, Animal
 Atrophy Antibodies  >1 publications with PRPF3 and Atrophy
 Brain Diseases Antibodies  >1 publications with PRPF3 and Brain Diseases
 Neurobehavioral Manifestations Antibodies  >1 publications with PRPF3 and Neurobehavioral Manifestations
 Liver Neoplasms Antibodies  >1 publications with PRPF3 and Liver Neoplasms
 Liver Neoplasms, Experimental Antibodies  >1 publications with PRPF3 and Liver Neoplasms, Experimental
 Liver Diseases Antibodies  >1 publications with PRPF3 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with PRPF3 and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >16 publications with PRPF3 and Eye
 Nerve Antibodies  >4 publications with PRPF3 and Nerve
 Brain Antibodies  >3 publications with PRPF3 and Brain
 Lung Antibodies  >2 publications with PRPF3 and Lung
 Ear Antibodies  >1 publications with PRPF3 and Ear
 Liver Antibodies  >1 publications with PRPF3 and Liver
 Mammary Gland Antibodies  >1 publications with PRPF3 and Mammary Gland
 Vascular Antibodies  >1 publications with PRPF3 and Vascular
 Muscle Antibodies  >1 publications with PRPF3 and Muscle
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