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TGF-beta1 elisa kit :: Porcine transforming growth factor beta1, TGF-beta1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9302475 TGF-beta1 elisa kit
Unit / Price
48-Strip-Wells  /  $500 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,250 +4 FREE 8GB USB
10x96-Strip-Wells  /  $6,395 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

transforming growth factor beta1, TGF-beta1, ELISA Kit

★Popular Item★
 Also Known As   

Porcine transforming growth factor beta1, TGF-beta1 ELISA Kit

 Product Synonym Names    Porcine transforming growth factor b1, TGF-b1 ELISA Kit
 Product Gene Name   

TGF-beta1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 7; NC_000073.6 (25687002..25704996). Location: 7 A3; 7 13.98 cM
 3D Structure    ModBase 3D Structure for P04202
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 Species Reactivity    Porcine
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TGF-beta1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TGF-beta1 purchase    MBS9302475 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the transforming growth factor beta1, TGF-beta1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TGF-beta1. The ELISA analytical biochemical technique of the MBS9302475 kit is based on TGF-beta1 antibody-TGF-beta1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TGF-beta1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TGF-beta1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TGF-beta1. It may not necessarily be applicable to this product.
 NCBI GI #    6755775
 NCBI GeneID    21803
 NCBI Accession #    NP_035707.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_011577.1 [Other Products]
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 UniProt Primary Accession #    P04202 [Other Products]
 UniProt Related Accession #    P04202 [Other Products]
 Molecular Weight    44,310 Da
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 NCBI Official Full Name    transforming growth factor beta-1
 NCBI Official Synonym Full Names    transforming growth factor, beta 1
 NCBI Official Symbol    Tgfb1 [Similar Products]
 NCBI Official Synonym Symbols   
Tgfb; Tgfb-1; TGFbeta1; TGF-beta1
[Similar Products]
 NCBI Protein Information    transforming growth factor beta-1; TGF-beta 1; TGF-beta-1; regulatory protein; transforming growth factor-beta 1
 UniProt Protein Name    Transforming growth factor beta-1
 UniProt Gene Name    Tgfb1 [Similar Products]
 UniProt Synonym Gene Names    TGF-beta-1; LAP [Similar Products]
 UniProt Entry Name    TGFB1_MOUSE
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 UniProt Comments for TGF-beta1    TGFB1: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Homodimer; disulfide-linked, or heterodimer with TGFB2. Secreted and stored as a biologically inactive form in the extracellular matrix in a 290 kDa complex (large latent TGF-beta1 complex) containing the TGFB1 homodimer, the latency-associated peptide (LAP), and the latent TGFB1 binding protein-1 (LTBP1). The complex without LTBP1 is known as the'small latent TGF-beta1 complex'. Dissociation of the TGFB1 from LAP is required for growth factor activation and biological activity. Release of the large latent TGF-beta1 complex from the extracellular matrix is carried out by the matrix metalloproteinase MMP3. May interact with THSD4; this interaction may lead to sequestration by FBN1 microfibril assembly and attenuation of TGFB signaling. Interacts with the serine proteases, HTRA1 and HTRA3: the interaction with either inhibits TGFB1-mediated signaling. The HTRA protease activity is required for this inhibition. Interacts with CD109, DPT and ASPN. Activated in vitro at pH below 3.5 and over 12.5. Highly expressed in bone. Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA). Co-localizes with ASPN in chondrocytes within OA lesions of articular cartilage. Belongs to the TGF-beta family.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted

Cellular Component: extracellular space; proteinaceous extracellular matrix; microvillus; cell surface; cell soma; cell; axon; cytoplasm; extracellular region; nucleus; secretory granule

Molecular Function: protein binding; enzyme binding; protein homodimerization activity; growth factor activity; protein heterodimerization activity; punt binding; cytokine activity; protein N-terminus binding; glycoprotein binding; transforming growth factor beta receptor binding; antigen binding

Biological Process: positive regulation of apoptosis; positive regulation of transcription, DNA-dependent; SMAD protein nuclear translocation; positive regulation of protein amino acid dephosphorylation; activation of NF-kappaB transcription factor; regulation of protein import into nucleus; positive regulation of MAP kinase activity; regulation of transforming growth factor beta receptor signaling pathway; negative regulation of ossification; cell cycle arrest; positive regulation of isotype switching to IgA isotypes; regulatory T cell differentiation; T cell differentiation; positive regulation of interleukin-17 production; regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; positive regulation of chemotaxis; positive regulation of smooth muscle cell differentiation; positive regulation of blood vessel endothelial cell migration; negative regulation of immune response; regulation of sodium ion transport; negative regulation of blood vessel endothelial cell migration; negative regulation of fat cell differentiation; lymph node development; positive regulation of protein secretion; regulation of MAPKKK cascade; positive regulation of cell division; positive regulation of transcription from RNA polymerase II promoter; response to progesterone stimulus; endoderm development; positive regulation of odontogenesis; myelination; negative regulation of phagocytosis; evasion of host defenses by virus; wound healing; T cell activation; positive regulation of cellular protein metabolic process; myeloid dendritic cell differentiation; negative regulation of transcription from RNA polymerase II promoter; phosphate metabolic process; response to organic substance; negative regulation of cell proliferation; CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment; negative regulation of T cell proliferation; mammary gland development; regulation of DNA binding; negative regulation of release of sequestered calcium ion into cytosol; positive regulation of cell proliferation; protein kinase B signaling cascade; protein export from nucleus; inflammatory response; positive regulation of exit from mitosis; epidermal growth factor receptor signaling pathway; mitotic cell cycle checkpoint; common-partner SMAD protein phosphorylation; positive regulation of phosphoinositide 3-kinase activity; positive regulation of peptidyl-serine phosphorylation; SMAD protein complex assembly; regulation of cell proliferation; positive regulation of protein kinase B signaling cascade; cell proliferation; negative regulation of interleukin-17 production; positive regulation of protein complex assembly; positive regulation of protein import into nucleus; epithelial to mesenchymal transition; negative regulation of cell-cell adhesion; negative regulation of cell growth; negative regulation of skeletal muscle development; mononuclear cell proliferation; protein amino acid phosphorylation; hyaluronan catabolic process; regulation of apoptosis; negative regulation of neuroblast proliferation; transforming growth factor beta receptor signaling pathway; positive regulation of superoxide release; receptor catabolic process; germ cell migration; chondrocyte differentiation; defense response to fungus, incompatible interaction; T cell homeostasis; negative regulation of mitotic cell cycle; cell growth; tolerance induction to self antigen; regulation of striated muscle development; organ regeneration; skeletal muscle development; cell activation; organ morphogenesis; negative regulation of DNA replication; hemopoietic progenitor cell differentiation; negative regulation of transcription, DNA-dependent; positive regulation of epithelial cell proliferation; positive regulation of collagen biosynthetic process; defense response; response to estradiol stimulus; regulation of interleukin-23 production; negative regulation of cell cycle; positive regulation of histone deacetylation; negative regulation of protein amino acid phosphorylation; lipopolysaccharide-mediated signaling pathway; adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; skeletal development; negative regulation of epithelial cell proliferation; intercellular junction assembly and maintenance; regulation of binding; MAPKKK cascade; morphogenesis of a branching structure; cellular calcium ion homeostasis; protein import into nucleus, translocation; ATP biosynthetic process; positive regulation of histone acetylation; positive regulation of protein amino acid phosphorylation; negative regulation of myoblast differentiation; negative regulation of T cell activation; growth; positive regulation of cell migration
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 Research Articles on TGF-beta1    1. Apc and TGF-beta signaling have roles in regulating the key transcriptional factor, Nkx2.1, for lung epithelial progenitor cell fate determination
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TGF-beta1 elisa kitPathways associated with TGF-beta1 elisa kit
 Reference Product  PubMed Publications
 Serpine1 elisa kit  >478 publications with TGF-beta1 and Serpine1
 Smad7 elisa kit  >463 publications with TGF-beta1 and Smad7
 Vegfa elisa kit  >97 publications with TGF-beta1 and Vegfa
 Dcn elisa kit  >81 publications with TGF-beta1 and Dcn
 Tgfbr2 elisa kit  >53 publications with TGF-beta1 and Tgfbr2
 Timp1 elisa kit  >46 publications with TGF-beta1 and Timp1
 Fn1 elisa kit  >17 publications with TGF-beta1 and Fn1
 Clu elisa kit  >14 publications with TGF-beta1 and Clu
 Actn1 elisa kit  >1 publications with TGF-beta1 and Actn1
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Signaling Pathway antibodies  Cell Cycle Signaling Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chronic Myeloid Leukemia Pathway antibodies  Chronic Myeloid Leukemia Pathway Diagram
Diseases associated with TGF-beta1 elisa kitOrgans/Tissues associated with TGF-beta1 elisa kit
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >4188 publications with TGF-beta1 and Fibrosis
 Lung Diseases Antibodies  >1289 publications with TGF-beta1 and Lung Diseases
 Liver Cirrhosis Antibodies  >729 publications with TGF-beta1 and Liver Cirrhosis
 Pulmonary Fibrosis Antibodies  >633 publications with TGF-beta1 and Pulmonary Fibrosis
 Hypertension Antibodies  >628 publications with TGF-beta1 and Hypertension
 Proteinuria Antibodies  >461 publications with TGF-beta1 and Proteinuria
 Diabetic Nephropathies Antibodies  >409 publications with TGF-beta1 and Diabetic Nephropathies
 Hypersensitivity Antibodies  >392 publications with TGF-beta1 and Hypersensitivity
 Asthma Antibodies  >359 publications with TGF-beta1 and Asthma
 Diabetes Mellitus, Experimental Antibodies  >323 publications with TGF-beta1 and Diabetes Mellitus, Experimental
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2857 publications with TGF-beta1 and Muscle
 Lung Antibodies  >1783 publications with TGF-beta1 and Lung
 Liver Antibodies  >1737 publications with TGF-beta1 and Liver
 Skin Antibodies  >1085 publications with TGF-beta1 and Skin
 Bone Marrow Antibodies  >719 publications with TGF-beta1 and Bone Marrow
 Embryonic Tissue Antibodies  >632 publications with TGF-beta1 and Embryonic Tissue
 Joint Antibodies  >558 publications with TGF-beta1 and Joint
 Eye Antibodies  >477 publications with TGF-beta1 and Eye
 Intestine Antibodies  >348 publications with TGF-beta1 and Intestine
 Spleen Antibodies  >247 publications with TGF-beta1 and Spleen
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