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AGPAT2 elisa kit :: Rabbit 1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7216895 AGPAT2 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2), ELISA Kit

★Popular Item★
 Also Known As   

Rabbit 1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2) ELISA Kit

 Product Gene Name   

AGPAT2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 608594
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 Species Reactivity    Rabbit
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AGPAT2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AGPAT2 purchase    MBS7216895 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AGPAT2. The ELISA analytical biochemical technique of the MBS7216895 kit is based on AGPAT2 antibody-AGPAT2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AGPAT2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AGPAT2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for AGPAT2. It may not necessarily be applicable to this product.
 NCBI GI #    69122971
 NCBI GeneID    10555
 NCBI Accession #    NP_001012745.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001012727.1 [Other Products]
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 UniProt Secondary Accession #    O00516; O15106; Q5VUD3; Q5VUD4; Q9BSV7; Q9BWR7 [Other Products]
 UniProt Related Accession #    O15120 [Other Products]
 Molecular Weight    27,279 Da
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 NCBI Official Full Name    1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform b
 NCBI Official Synonym Full Names    1-acylglycerol-3-phosphate O-acyltransferase 2
 NCBI Official Symbol    AGPAT2 [Similar Products]
 NCBI Official Synonym Symbols   
BSCL; BSCL1; LPAAB; 1-AGPAT2; LPAAT-beta
[Similar Products]
 NCBI Protein Information    1-acyl-sn-glycerol-3-phosphate acyltransferase beta; 1-AGPAT 2; 1-AGP acyltransferase 2; lysophosphatidic acid acyltransferase beta; lysophosphatidic acid acyltransferase-beta; 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
 UniProt Protein Name    1-acyl-sn-glycerol-3-phosphate acyltransferase beta
 UniProt Synonym Protein Names   
1-acylglycerol-3-phosphate O-acyltransferase 2; 1-AGP acyltransferase 2; 1-AGPAT 2; Lysophosphatidic acid acyltransferase beta; LPAAT-beta
 Protein Family    1-acyl-sn-glycerol-3-phosphate acyltransferase
 UniProt Gene Name    AGPAT2 [Similar Products]
 UniProt Synonym Gene Names    1-AGP acyltransferase 2; 1-AGPAT 2; LPAAT-beta [Similar Products]
 UniProt Entry Name    PLCB_HUMAN
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 NCBI Summary for AGPAT2    This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
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 UniProt Comments for AGPAT2    AGPAT2: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Defects in AGPAT2 are the cause of congenital generalized lipodystrophy type 1 (CGL1); also known as Berardinelli-Seip congenital lipodystrophy type 1 (BSCL1) or Berardinelli-Seip syndrome. CGL1 is an autosomal recessive disorder characterized by marked paucity of adipose tissue, extreme insulin resistance, hypertriglyceridemia, hepatic steatosis and early onset of diabetes. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.3.1.51; Membrane protein, integral; Transferase; Lipid Metabolism - ether lipid; Lipid Metabolism - glycerolipid; Membrane protein, multi-pass; Lipid Metabolism - glycerophospholipid

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane

Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity

Biological Process: positive regulation of cytokine production; epidermis development; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; CDP-diacylglycerol biosynthetic process; positive regulation of cytokine and chemokine mediated signaling pathway

Disease: Lipodystrophy, Congenital Generalized, Type 1
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 Research Articles on AGPAT2    1. the ability of LPAAT-beta to regulate mTOR function
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AGPAT2 elisa kitPathways associated with AGPAT2 elisa kit
 Reference Product  PubMed Publications
 PLD1 elisa kit  >1 publications with AGPAT2 and PLD1
 LPIN1 elisa kit  >1 publications with AGPAT2 and LPIN1
 AGPAT9 elisa kit  >1 publications with AGPAT2 and AGPAT9
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 CDP-diacylglycerol Biosynthesis I Pathway antibodies  CDP-diacylglycerol Biosynthesis I Pathway Diagram
 CDP-diacylglycerol Biosynthesis I Pathway antibodies  CDP-diacylglycerol Biosynthesis I Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
Diseases associated with AGPAT2 elisa kitOrgans/Tissues associated with AGPAT2 elisa kit
 Disease Name  Pubmed Publications
 Lipodystrophy, Congenital Generalized Antibodies  >48 publications with AGPAT2 and Lipodystrophy, Congenital Generalized
 Liver Diseases Antibodies  >12 publications with AGPAT2 and Liver Diseases
 Hypertrophy Antibodies  >11 publications with AGPAT2 and Hypertrophy
 Congenital Abnormalities Antibodies  >9 publications with AGPAT2 and Congenital Abnormalities
 Heart Diseases Antibodies  >5 publications with AGPAT2 and Heart Diseases
 Hepatomegaly Antibodies  >5 publications with AGPAT2 and Hepatomegaly
 Nervous System Diseases Antibodies  >4 publications with AGPAT2 and Nervous System Diseases
 Kidney Diseases Antibodies  >4 publications with AGPAT2 and Kidney Diseases
 Fatty Liver Antibodies  >4 publications with AGPAT2 and Fatty Liver
 Brain Diseases Antibodies  >3 publications with AGPAT2 and Brain Diseases
 Organ/Tissue Name  Pubmed Publications
 Adipose Tissue Antibodies  >39 publications with AGPAT2 and Adipose Tissue
 Liver Antibodies  >14 publications with AGPAT2 and Liver
 Blood Antibodies  >13 publications with AGPAT2 and Blood
 Connective Tissue Antibodies  >13 publications with AGPAT2 and Connective Tissue
 Muscle Antibodies  >12 publications with AGPAT2 and Muscle
 Kidney Antibodies  >5 publications with AGPAT2 and Kidney
 Bone Antibodies  >5 publications with AGPAT2 and Bone
 Ovary Antibodies  >4 publications with AGPAT2 and Ovary
 Skin Antibodies  >3 publications with AGPAT2 and Skin
 Heart Antibodies  >3 publications with AGPAT2 and Heart
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