AAA36182.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
74,804 Da
NCBI Official Full Name
15-lipoxygenase
NCBI Official Synonym Full Names
arachidonate 15-lipoxygenase
NCBI Protein Information
arachidonate 15-lipoxygenase; 15-LOX; 12/15-lipoxygenase; 15-lipooxygenase-1; arachidonate omega-6 lipoxygenase; arachidonate 12-lipoxygenase, leukocyte-type
UniProt Protein Name
Arachidonate 15-lipoxygenase
UniProt Synonym Protein Names
12/15-lipoxygenase; Arachidonate 12-lipoxygenase, leukocyte-type (EC:1.13.11.31); 12-LOX; Arachidonate omega-6 lipoxygenase
UniProt Synonym Gene Names
UniProt Entry Name
LOX15_HUMAN
UniProt Comments for 15-LO / LOX
ALOX15: Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Belongs to the lipoxygenase family.
Protein type: EC 1.13.11.31; Motility/polarity/chemotaxis; Lipid Metabolism - linoleic acid; EC 1.13.11.33; Lipid Metabolism - arachidonic acid; Oxidoreductase
Chromosomal Location of Human Ortholog: 17p13.3
Cellular Component: extrinsic to internal side of plasma membrane; membrane; plasma membrane; lipid particle; cytosol
Molecular Function: arachidonate 12-lipoxygenase activity; protein binding; phosphatidylinositol-4,5-bisphosphate binding; hepoxilin A3 synthase activity; arachidonate 15-lipoxygenase activity; hepoxilin-epoxide hydrolase activity; iron ion binding
Biological Process: ossification; positive regulation of heterotypic cell-cell adhesion; lipoxygenase pathway; wound healing; positive regulation of actin filament polymerization; negative regulation of adaptive immune response; phosphatidylethanolamine biosynthetic process; arachidonic acid metabolic process; leukotriene metabolic process; hepoxilin biosynthetic process; inflammatory response; apoptotic cell clearance; bone mineralization
Research Articles on 15-LO / LOX
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Products associated with 15-LO / LOX elisa kit
Pathways associated with 15-LO / LOX elisa kit
Diseases associated with 15-LO / LOX elisa kit
Organs/Tissues associated with 15-LO / LOX elisa kit
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