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HSD17B14 elisa kit :: Rabbit 17-beta-hydroxysteroid dehydrogenase 14 (HSD17B14) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS727557 HSD17B14 elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

17-beta-hydroxysteroid dehydrogenase 14 (HSD17B14), ELISA Kit

 Also Known As   

Rabbit 17-beta-hydroxysteroid dehydrogenase 14 (HSD17B14) ELISA Kit

 Product Gene Name   

HSD17B14 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    612832
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 Species Reactivity    Rabbit
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    1.0-25ng/mL
 Sensitivity    0.1ng/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HSD17B14 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HSD17B14 purchase    MBS727557 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 17-beta-hydroxysteroid dehydrogenase 14 (HSD17B14) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.0-25ng/mL in biological research samples containing HSD17B14, with an estimated sensitivity of 0.1ng/mL. The ELISA analytical biochemical technique of the MBS727557 kit is based on HSD17B14 antibody-HSD17B14 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HSD17B14 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HSD17B14. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for HSD17B14 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for HSD17B14. It may not necessarily be applicable to this product.
 NCBI GI #    59889578
 NCBI GeneID    51171
 NCBI Accession #    NP_057330.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_016246.2 [Other Products]
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 UniProt Secondary Accession #    Q9UKU3 [Other Products]
 UniProt Related Accession #    Q9BPX1 [Other Products]
 Molecular Weight    28,317 Da [Similar Products]
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 NCBI Official Full Name    17-beta-hydroxysteroid dehydrogenase 14
 NCBI Official Synonym Full Names    hydroxysteroid (17-beta) dehydrogenase 14
 NCBI Official Symbol    HSD17B14 [Similar Products]
 NCBI Official Synonym Symbols   
DHRS10; SDR47C1; retSDR3
[Similar Products]
 NCBI Protein Information    17-beta-hydroxysteroid dehydrogenase 14; 17-beta-HSD 14; 17-beta-hydroxysteroid dehydrogenase DHRS10; dehydrogenase/reductase SDR family member 10; retinal short-chain dehydrogenase/reductase 3; retinal short-chain dehydrogenase/reductase retSDR3; short chain dehydrogenase/reductase family 47C, member 1
 UniProt Protein Name    17-beta-hydroxysteroid dehydrogenase 14
 UniProt Synonym Protein Names   
17-beta-hydroxysteroid dehydrogenase DHRS10; Dehydrogenase/reductase SDR family member 10; Retinal short-chain dehydrogenase/reductase retSDR3
 Protein Family    17-beta-hydroxysteroid dehydrogenase
 UniProt Gene Name    HSD17B14 [Similar Products]
 UniProt Synonym Gene Names    DHRS10; SDR3; UNQ502/PRO474; 17-beta-HSD 14 [Similar Products]
 UniProt Entry Name    DHB14_HUMAN
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 NCBI Summary for HSD17B14    17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]
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 UniProt Comments for HSD17B14    HSD17B14: Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3- beta,17-beta-diol (in vitro). Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein type: EC 1.1.1.-; Oxidoreductase

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: cytosol

Molecular Function: estradiol 17-beta-dehydrogenase activity; testosterone 17-beta-dehydrogenase (NADP+) activity; protein binding

Biological Process: steroid catabolic process
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 Research Articles on HSD17B14    1. Results show that tumoural expression levels of 17betaHSD14 can predict the outcome of adjuvant tamoxifen treatment in terms of local recurrence-free survival in patients with lymph node-negative ER+ breast cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with HSD17B14 elisa kitOrgans/Tissues associated with HSD17B14 elisa kit
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with HSD17B14 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >1 publications with HSD17B14 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Lymph Antibodies  >1 publications with HSD17B14 and Lymph
 Placenta Antibodies  >1 publications with HSD17B14 and Placenta
 Testis Antibodies  >1 publications with HSD17B14 and Testis
 Uncharacterized Tissue Antibodies  >1 publications with HSD17B14 and Uncharacterized Tissue
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