NP_001164624.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,500 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 1D
NCBI Official Synonym Symbols
NCBI Protein Information
5-hydroxytryptamine receptor 1D
UniProt Protein Name
5-hydroxytryptamine receptor 1D
UniProt Synonym Protein Names
5-HT-1D-alpha; Serotonin receptor 1D
UniProt Synonym Gene Names
UniProt Comments for HTR1D
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction ().
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Diseases associated with HTR1D elisa kit
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