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ADAMTSL2 elisa kit :: Rabbit ADAMTS-like protein 2 (ADAMTSL2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7206221 ADAMTSL2 elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADAMTS-like protein 2 (ADAMTSL2), ELISA Kit

 Also Known As   

Rabbit ADAMTS-like protein 2 (ADAMTSL2) ELISA Kit

 Product Gene Name   

ADAMTSL2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    612277
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 Species Reactivity    Rabbit
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ADAMTSL2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ADAMTSL2 purchase    MBS7206221 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ADAMTS-like protein 2 (ADAMTSL2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ADAMTSL2. The ELISA analytical biochemical technique of the MBS7206221 kit is based on ADAMTSL2 antibody-ADAMTSL2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADAMTSL2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADAMTSL2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for ADAMTSL2 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for ADAMTSL2. It may not necessarily be applicable to this product.
 NCBI GI #    223718260
 NCBI GeneID    9719
 NCBI Accession #    NP_001138792.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001145320.1 [Other Products]
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 UniProt Secondary Accession #    O60345; B1B0D5 [Other Products]
 UniProt Related Accession #    Q86TH1 [Other Products]
 Molecular Weight    104,621 Da
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 NCBI Official Full Name    ADAMTS-like protein 2
 NCBI Official Synonym Full Names    ADAMTS-like 2
 NCBI Official Symbol    ADAMTSL2 [Similar Products]
 NCBI Official Synonym Symbols   
GPHYSD1
[Similar Products]
 NCBI Protein Information    ADAMTS-like protein 2; ADAMTSL-2
 UniProt Protein Name    ADAMTS-like protein 2
 Protein Family    ADAMTS-like protein
 UniProt Gene Name    ADAMTSL2 [Similar Products]
 UniProt Synonym Gene Names    KIAA0605; ADAMTSL-2 [Similar Products]
 UniProt Entry Name    ATL2_HUMAN
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 NCBI Summary for ADAMTSL2    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. [provided by RefSeq, Feb 2009]
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 UniProt Comments for ADAMTSL2    ADAMTSL2: Defects in ADAMTSL2 are the cause of geleophysic dysplasia type 1 (GPHYSD1). An autosomal recessive disorder characterized by severe short stature, short hands and feet, joint limitations, and skin thickening. Radiologic features include delayed bone age, cone-shaped epiphyses, shortened long tubular bones, and ovoid vertebral bodies. Affected individuals have characteristic facial features including a 'happy' face with full cheeks, shortened nose, hypertelorism, long and flat philtrum, and thin upper lip. Other distinctive features include progressive cardiac valvular thickening often leading to an early death, toe walking, tracheal stenosis, respiratory insufficiency, and lysosomal-like storage vacuoles in various tissues.

Protein type: Secreted, signal peptide; Protease; Secreted; Extracellular matrix

Chromosomal Location of Human Ortholog: 9q34.2

Cellular Component: proteinaceous extracellular matrix

Molecular Function: protein binding; zinc ion binding; metalloendopeptidase activity

Biological Process: proteolysis; negative regulation of transforming growth factor beta receptor signaling pathway

Disease: Geleophysic Dysplasia 1
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 Research Articles on ADAMTSL2    1. Two novel homozygous missense mutations in the ADAMTSL2 gene underlie geleophysic dysplasia in two consanguineous families from the United Arab Emirates.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ADAMTSL2 elisa kitPathways associated with ADAMTSL2 elisa kit
 Reference Product  PubMed Publications
 SMAD2 elisa kit  >2 publications with ADAMTSL2 and SMAD2
 LTBP1 elisa kit  >1 publications with ADAMTSL2 and LTBP1
 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 O-glycosylation Of TSR Domain-containing Proteins Pathway antibodies  O-glycosylation Of TSR Domain-containing Proteins Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
Diseases associated with ADAMTSL2 elisa kitOrgans/Tissues associated with ADAMTSL2 elisa kit
 Disease Name  Pubmed Publications
 GELEOPHYSIC DYSPLASIA 1 Antibodies  >11 publications with ADAMTSL2 and GELEOPHYSIC DYSPLASIA 1
 Congenital Abnormalities Antibodies  >10 publications with ADAMTSL2 and Congenital Abnormalities
 Acromicric dysplasia Antibodies  >9 publications with ADAMTSL2 and Acromicric dysplasia
 Growth Disorders Antibodies  >4 publications with ADAMTSL2 and Growth Disorders
 Heart Defects, Congenital Antibodies  >3 publications with ADAMTSL2 and Heart Defects, Congenital
 Hand Deformities, Congenital Antibodies  >2 publications with ADAMTSL2 and Hand Deformities, Congenital
 Facies Antibodies  >1 publications with ADAMTSL2 and Facies
 Hepatomegaly Antibodies  >1 publications with ADAMTSL2 and Hepatomegaly
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >4 publications with ADAMTSL2 and Connective Tissue
 Eye Antibodies  >2 publications with ADAMTSL2 and Eye
 Lung Antibodies  >2 publications with ADAMTSL2 and Lung
 Muscle Antibodies  >1 publications with ADAMTSL2 and Muscle
 Pancreas Antibodies  >1 publications with ADAMTSL2 and Pancreas
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