NP_003797.1
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NCBI GenBank Nucleotide #
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UniProt Related Accession #
Molecular Weight
9,884 Da
NCBI Official Full Name
activator of apoptosis harakiri
NCBI Official Synonym Full Names
harakiri, BCL2 interacting protein
NCBI Protein Information
activator of apoptosis harakiri; death protein 5; BCL2-interacting protein; activator of apoptosis Hrk; neuronal death protein DP5; BH3-interacting domain-containing protein 3; harakiri, BCL2 interacting protein (contains only BH3 domain)
UniProt Protein Name
Activator of apoptosis harakiri
UniProt Synonym Protein Names
BH3-interacting domain-containing protein 3; Neuronal death protein DP5
UniProt Synonym Gene Names
UniProt Entry Name
HRK_HUMAN
NCBI Summary for HRK
This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
UniProt Comments for HRK
HRK: Promotes apoptosis.
Protein type: Apoptosis; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12q24.22
Cellular Component: mitochondrion; integral to membrane
Molecular Function: protein binding
Biological Process: positive regulation of protein homooligomerization; apoptosis; positive regulation of apoptosis
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Products associated with HRK elisa kit
Pathways associated with HRK elisa kit
Diseases associated with HRK elisa kit
Organs/Tissues associated with HRK elisa kit
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