NP_001229304.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
8,521 Da
NCBI Official Full Name
anaphase-promoting complex subunit 13
NCBI Official Synonym Full Names
anaphase promoting complex subunit 13
NCBI Official Synonym Symbols
NCBI Protein Information
anaphase-promoting complex subunit 13; cyclosome subunit 13
UniProt Protein Name
Anaphase-promoting complex subunit 13
UniProt Synonym Protein Names
Cyclosome subunit 13
UniProt Synonym Gene Names
UniProt Entry Name
APC13_HUMAN
NCBI Summary for ANAPC13
This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined. [provided by RefSeq, Nov 2008]
UniProt Comments for ANAPC13
APC13: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Belongs to the APC13 family.
Protein type: Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 3q22.2
Cellular Component: anaphase-promoting complex
Biological Process: mitosis; cell division
Research Articles on ANAPC13
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Products associated with ANAPC13 elisa kit
Pathways associated with ANAPC13 elisa kit
Diseases associated with ANAPC13 elisa kit
Organs/Tissues associated with ANAPC13 elisa kit
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