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APOC3 elisa kit :: Rabbit Apolipoprotein C3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS016104
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Apolipoprotein C3 (APOC3), ELISA Kit

 Also Known As   

Rabbit Apolipoprotein C3 ELISA Kit

 Product Gene Name   

APOC3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 Chromosome Location    Chromosome: 11; NC_000011.9 (116700624..116703787). Location: 11q23.3
 OMIM    107720
 3D Structure    ModBase 3D Structure for P02656
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 Species Reactivity    Rabbit
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 Specificity    No significant cross-reactivity or interference between Rabbit APOC3 and analogues was observed.
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 Samples    Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids
 Assay Type    Sandwich
 Detection Range    3.12 ug/ml 100 ug/ml.
 Sensitivity    1.0 ug/ml.
 Intended Uses    ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate APOC3 concentrations in Rabbit serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean x100]
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of APOC3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for APOC3 purchase    MBS016104 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Apolipoprotein C3 (APOC3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 3.12 ug/ml 100 ug/ml in biological research samples containing APOC3, with an estimated sensitivity of 1.0 ug/ml. The ELISA analytical biochemical technique of the MBS016104 kit is based on APOC3 antibody-APOC3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect APOC3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, APOC3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for APOC3 elisa kit

   Introduction: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate APOC3 concentrations in Rabbit serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications!
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 Typical Testing Data/Standard Curve (for reference only) of APOC3 elisa kit    APOC3 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS016104
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NCBI/Uniprot data below describe general gene information for APOC3. It may not necessarily be applicable to this product.
 NCBI GI #    4557323
 NCBI GeneID    345
 NCBI Accession #    NP_000031.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000040.1 [Other Products]
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 UniProt Primary Accession #    P02656 [Other Products]
 UniProt Secondary Accession #    Q08E83; Q6Q786 [Other Products]
 UniProt Related Accession #    P02656 [Other Products]
 Molecular Weight    10,852 Da
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 NCBI Official Full Name    apolipoprotein C-III
 NCBI Official Synonym Full Names    apolipoprotein C-III
 NCBI Official Symbol    APOC3 [Similar Products]
 NCBI Official Synonym Symbols   
HALP2; APOCIII
[Similar Products]
 NCBI Protein Information    apolipoprotein C-III; apo-CIII; apoC-III; apolipoprotein C3
 UniProt Protein Name    Apolipoprotein C-III
 UniProt Synonym Protein Names   
Apolipoprotein C3
 Protein Family    Apolipoprotein
 UniProt Gene Name    APOC3 [Similar Products]
 UniProt Synonym Gene Names    Apo-CIII; ApoC-III [Similar Products]
 UniProt Entry Name    APOC3_HUMAN
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 NCBI Summary for APOC3    Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia. [provided by RefSeq, Jul 2008]
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 UniProt Comments for APOC3    APOC3: Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles. Defects in APOC3 are the cause of hyperalphalipoproteinemia type 2 (HALP2). HALP2 is a condition characterized by high levels of high density lipoprotein (HDL) and increased HDL cholesterol levels. Belongs to the apolipoprotein C3 family.

Protein type: Lipid-binding; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: extracellular space; chylomicron; early endosome; extracellular region

Molecular Function: lipase inhibitor activity; cholesterol binding; phospholipid binding; enzyme regulator activity

Biological Process: response to drug; response to peptide hormone stimulus; cholesterol metabolic process; phototransduction, visible light; regulation of Cdc42 protein signal transduction; cholesterol efflux; lipoprotein metabolic process; G-protein coupled receptor protein signaling pathway; cholesterol homeostasis; reverse cholesterol transport; triacylglycerol metabolic process; negative regulation of lipid catabolic process; phospholipid efflux; lipoprotein transport; triacylglycerol catabolic process; negative regulation of receptor-mediated endocytosis; negative regulation of lipoprotein lipase activity; negative regulation of lipid metabolic process; inflammatory response; retinoid metabolic process; triacylglycerol mobilization; response to nutrient; negative regulation of fatty acid biosynthetic process

Disease: Apolipoprotein C-iii Deficiency
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 Research Articles on APOC3    1. Measurement of plasma ApoCIII may improve CAD prediction in the general population
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with APOC3 elisa kitPathways associated with APOC3 elisa kit
 Reference Product  PubMed Publications
 APOE elisa kit  >63 publications with APOC3 and APOE
 APOA5 elisa kit  >60 publications with APOC3 and APOA5
 APOA1 elisa kit  >58 publications with APOC3 and APOA1
 LPL elisa kit  >46 publications with APOC3 and LPL
 APOB elisa kit  >44 publications with APOC3 and APOB
 APOA4 elisa kit  >37 publications with APOC3 and APOA4
 APOC2 elisa kit  >11 publications with APOC3 and APOC2
 APOA2 elisa kit  >8 publications with APOC3 and APOA2
 PPARG elisa kit  >5 publications with APOC3 and PPARG
 INS elisa kit  >2 publications with APOC3 and INS
 Products by Pathway  Pathway Diagram
 Chylomicron-mediated Lipid Transport Pathway antibodies  Chylomicron-mediated Lipid Transport Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Visual Transduction Pathway antibodies  Diseases Associated With Visual Transduction Pathway Diagram
 HDL-mediated Lipid Transport Pathway antibodies  HDL-mediated Lipid Transport Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Lipoprotein Metabolism Pathway antibodies  Lipoprotein Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
Diseases associated with APOC3 elisa kitOrgans/Tissues associated with APOC3 elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >71 publications with APOC3 and Cardiovascular Diseases
 Coronary Disease Antibodies  >48 publications with APOC3 and Coronary Disease
 Hypertriglyceridemia Antibodies  >44 publications with APOC3 and Hypertriglyceridemia
 Dyslipidemias Antibodies  >44 publications with APOC3 and Dyslipidemias
 Heart Diseases Antibodies  >44 publications with APOC3 and Heart Diseases
 Hyperlipidemias Antibodies  >36 publications with APOC3 and Hyperlipidemias
 Atherosclerosis Antibodies  >33 publications with APOC3 and Atherosclerosis
 Insulin Resistance Antibodies  >32 publications with APOC3 and Insulin Resistance
 Obesity Antibodies  >28 publications with APOC3 and Obesity
 Hyperinsulinism Antibodies  >26 publications with APOC3 and Hyperinsulinism
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >41 publications with APOC3 and Liver
 Heart Antibodies  >36 publications with APOC3 and Heart
 Connective Tissue Antibodies  >7 publications with APOC3 and Connective Tissue
 Kidney Antibodies  >4 publications with APOC3 and Kidney
 Muscle Antibodies  >2 publications with APOC3 and Muscle
 Brain Antibodies  >2 publications with APOC3 and Brain
 Lung Antibodies  >1 publications with APOC3 and Lung
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