NP_444475.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,212 Da
NCBI Official Full Name
aryl-hydrocarbon-interacting protein-like 1
NCBI Official Synonym Full Names
aryl hydrocarbon receptor-interacting protein-like 1
NCBI Protein Information
aryl-hydrocarbon-interacting protein-like 1
UniProt Protein Name
Aryl-hydrocarbon-interacting protein-like 1
UniProt Entry Name
AIPL1_MOUSE
UniProt Comments for AIPL1
AIPL1: May be important in protein trafficking and/or protein folding and stabilization. Defects in AIPL1 are the cause of Leber congenital amaurosis type 4 (LCA4). LCA designates a clinically and genetically heterogeneous group of childhood retinal degenerations, generally inherited in an autosomal recessive manner. Affected infants have little or no retinal photoreceptor function as tested by electroretinography. LCA represents the most common genetic cause of congenital visual impairment in infants and children. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Chaperone; Apoptosis
Cellular Component: photoreceptor inner segment; cytoplasm; nucleus
Molecular Function: farnesylated protein binding
Biological Process: retinal homeostasis; phototransduction, visible light; protein farnesylation; protein folding; regulation of cGMP metabolic process; negative regulation of apoptosis
Research Articles on AIPL1
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Diseases associated with AIPL1 elisa kit
Organs/Tissues associated with AIPL1 elisa kit
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