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BMP15 elisa kit :: Rabbit Bone Morphogenetic Protein 15 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS724309 BMP15 elisa kit
Unit / Price
48-Strip-Wells  /  $455 +1 FREE 8GB USB
96-Strip-Wells  /  $660 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Bone Morphogenetic Protein 15 (BMP15), ELISA Kit

 Also Known As   

Rabbit Bone Morphogenetic Protein 15 ELISA Kit

 Product Gene Name   

BMP15 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 300510
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 Species Reactivity    Rabbit
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Sandwich
 Detection Range    250-5000pg/mL
 Sensitivity    1.0pg/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of BMP15 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BMP15 purchase    MBS724309 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Bone Morphogenetic Protein 15 (BMP15) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 250-5000pg/mL in biological research samples containing BMP15, with an estimated sensitivity of 1.0pg/mL. The ELISA analytical biochemical technique of the MBS724309 kit is based on BMP15 antibody-BMP15 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BMP15 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BMP15. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for BMP15 elisa kit    Cardiovascular
NCBI/Uniprot data below describe general gene information for BMP15. It may not necessarily be applicable to this product.
 NCBI GI #    257743454
 NCBI GeneID    9210
 NCBI Accession #    NP_005439.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_005448.2 [Other Products]
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 UniProt Secondary Accession #    Q17RM6; Q5JST1; Q9UMS1 [Other Products]
 UniProt Related Accession #    O95972 [Other Products]
 Molecular Weight    45,055 Da
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 NCBI Official Full Name    bone morphogenetic protein 15
 NCBI Official Synonym Full Names    bone morphogenetic protein 15
 NCBI Official Symbol    BMP15 [Similar Products]
 NCBI Official Synonym Symbols   
ODG2; POF4; GDF9B
[Similar Products]
 NCBI Protein Information    bone morphogenetic protein 15; BMP-15; GDF-9B; growth/differentiation factor 9B
 UniProt Protein Name    Bone morphogenetic protein 15
 UniProt Synonym Protein Names   
Growth/differentiation factor 9B; GDF-9B
 Protein Family    Bone morphogenetic protein
 UniProt Gene Name    BMP15 [Similar Products]
 UniProt Synonym Gene Names    GDF9B; BMP-15; GDF-9B [Similar Products]
 UniProt Entry Name    BMP15_HUMAN
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 NCBI Summary for BMP15    The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9. Defects in this gene are the cause of ovarian dysgenesis 2.[provided by RefSeq, Sep 2009]
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 UniProt Comments for BMP15    BMP15: May be involved in follicular development. Oocyte- specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. Defects in BMP15 are the cause of ovarian dysgenesis type 2 (ODG2); also known as X-linked hypergonadotropic ovarian dysgenesis or hypergonadotropic ovarian failure due to ovarian dysgenesis. Ovarian dysgenesis leads to ovarian failure and accounts for about half of the cases of primary amenorrhea. Defects in BMP15 are the cause of premature ovarian failure type 4 (POF4). An ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol. Belongs to the TGF-beta family.

Protein type: Secreted; Secreted, signal peptide; Cytokine

Chromosomal Location of Human Ortholog: Xp11.2

Cellular Component: extracellular space; cytoplasm

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: regulation of apoptosis; BMP signaling pathway; ovarian follicle development; granulosa cell development; positive regulation of transcription, DNA-dependent; regulation of MAPKKK cascade; female gamete generation; cell development

Disease: Ovarian Dysgenesis 2
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 Research Articles on BMP15    1. BMP15 down-regulates StAR expression and decreases progesterone production in human granulosa cells, likely via ALK3-mediated SMAD1/5/8 signaling.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BMP15 elisa kitPathways associated with BMP15 elisa kit
 Reference Product  PubMed Publications
 BMPR2 elisa kit  >36 publications with BMP15 and BMPR2
 BMPR1B elisa kit  >21 publications with BMP15 and BMPR1B
 FSHR elisa kit  >17 publications with BMP15 and FSHR
 ZAR1 elisa kit  >9 publications with BMP15 and ZAR1
 H1FOO elisa kit  >8 publications with BMP15 and H1FOO
 FIGLA elisa kit  >6 publications with BMP15 and FIGLA
 BTG4 elisa kit  >2 publications with BMP15 and BTG4
 FGF7 elisa kit  >2 publications with BMP15 and FGF7
 POF1B elisa kit  >1 publications with BMP15 and POF1B
 Products by Pathway  Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
Diseases associated with BMP15 elisa kit
 Disease Name  Pubmed Publications
 Infertility, Female Antibodies  >59 publications with BMP15 and Infertility, Female
 Polycystic Ovary Syndrome Antibodies  >16 publications with BMP15 and Polycystic Ovary Syndrome
 Ovarian Cysts Antibodies  >13 publications with BMP15 and Ovarian Cysts
 Disorders of Sex Development Antibodies  >8 publications with BMP15 and Disorders of Sex Development
 Urogenital Abnormalities Antibodies  >8 publications with BMP15 and Urogenital Abnormalities
 Necrosis Antibodies  >4 publications with BMP15 and Necrosis
 Nervous System Diseases Antibodies  >3 publications with BMP15 and Nervous System Diseases
 Mental Disorders Antibodies  >2 publications with BMP15 and Mental Disorders
 Immune System Diseases Antibodies  >2 publications with BMP15 and Immune System Diseases
 Weight Loss Antibodies  >2 publications with BMP15 and Weight Loss
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