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C8gamma elisa kit :: Rabbit Complement Component 8G ELISA Kit

Scan QR to view Datasheet Catalog #    MBS029357 C8gamma elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Complement Component 8G (C8gamma), ELISA Kit

 Also Known As   

Rabbit Complement Component 8G ELISA Kit

 Product Gene Name   

C8gamma elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 9; NC_000009.11 (139839698..139841426). Location: 9q34.3
 OMIM    120930
 3D Structure    ModBase 3D Structure for P07360
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 Species Reactivity    Rabbit
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of C8gamma elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for C8gamma purchase    MBS029357 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Complement Component 8G (C8gamma) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing C8gamma. The ELISA analytical biochemical technique of the MBS029357 kit is based on C8gamma antibody-C8gamma antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect C8gamma antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, C8gamma. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for C8gamma. It may not necessarily be applicable to this product.
 NCBI GI #    166197660
 NCBI GeneID    733
 NCBI Accession #    NP_000597.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000606.2 [Other Products]
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 UniProt Primary Accession #    P07360 [Other Products]
 UniProt Secondary Accession #    Q14CT8; Q14CU0; Q5SQ07 [Other Products]
 UniProt Related Accession #    P07360 [Other Products]
 Molecular Weight    22,277 Da
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 NCBI Official Full Name    complement component C8 gamma chain
 NCBI Official Synonym Full Names    complement component 8, gamma polypeptide
 NCBI Official Symbol    C8G [Similar Products]
 NCBI Official Synonym Symbols   
C8C
[Similar Products]
 NCBI Protein Information    complement component C8 gamma chain
 UniProt Protein Name    Complement component C8 gamma chain
 UniProt Gene Name    C8G [Similar Products]
 UniProt Entry Name    CO8G_HUMAN
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 NCBI Summary for C8gamma    The protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity. [provided by RefSeq, Jul 2011]
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 UniProt Comments for C8gamma    C8G: C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Belongs to the calycin superfamily. Lipocalin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: membrane attack complex; extracellular region

Molecular Function: complement binding; protein complex binding; retinol binding

Biological Process: cytolysis; complement activation, alternative pathway; regulation of complement activation; innate immune response; complement activation, classical pathway
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 Research Articles on C8gamma    1. Binding of C8 gamma subunit to C8 beta is dependent on the thrombospondin type 1 module + low-density lipoprotein receptor class A module + membrane attack complex/perforin domain of C8 beta.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with C8gamma elisa kitPathways associated with C8gamma elisa kit
 Reference Product  PubMed Publications
 C8A elisa kit  >8 publications with C8gamma and C8A
 C8B elisa kit  >7 publications with C8gamma and C8B
 LCN1 elisa kit  >2 publications with C8gamma and LCN1
 PAEP elisa kit  >1 publications with C8gamma and PAEP
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Prion Diseases Pathway antibodies  Prion Diseases Pathway Diagram
 Prion Diseases Pathway antibodies  Prion Diseases Pathway Diagram
Diseases associated with C8gamma elisa kitOrgans/Tissues associated with C8gamma elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >3 publications with C8gamma and Inflammation
 Liver Diseases Antibodies  >2 publications with C8gamma and Liver Diseases
 Death Antibodies  >1 publications with C8gamma and Death
 Drug Toxicity Antibodies  >1 publications with C8gamma and Drug Toxicity
 Kidney Diseases Antibodies  >1 publications with C8gamma and Kidney Diseases
 Fatty Liver Antibodies  >1 publications with C8gamma and Fatty Liver
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >6 publications with C8gamma and Liver
 Kidney Antibodies  >2 publications with C8gamma and Kidney
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