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EMA elisa kit :: Rabbit Epithelial Membrane Antigen ELISA Kit

Scan QR to view Datasheet Catalog #    MBS018314 EMA elisa kit
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Epithelial Membrane Antigen (EMA), ELISA Kit

 Also Known As   

Rabbit Epithelial Membrane Antigen ELISA Kit

 Product Gene Name   

EMA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q02496
 Species Reactivity    Rabbit
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of EMA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for EMA purchase    MBS018314 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Epithelial Membrane Antigen (EMA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing EMA. The ELISA analytical biochemical technique of the MBS018314 kit is based on EMA antibody-EMA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect EMA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, EMA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for EMA. It may not necessarily be applicable to this product.
 NCBI GI #    199837
 NCBI GeneID    17829
 NCBI Accession #    AAA39754.1 [Other Products]
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 UniProt Primary Accession #    Q02496 [Other Products]
 UniProt Related Accession #    Q02496 [Other Products]
 Molecular Weight    64,539 Da
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 NCBI Official Full Name    episialin
 NCBI Official Synonym Full Names    mucin 1, transmembrane
 NCBI Official Symbol    Muc1 [Similar Products]
 NCBI Official Synonym Symbols   
EMA; CD227; Muc-1
[Similar Products]
 NCBI Protein Information    mucin-1; episialin
 UniProt Protein Name    Mucin-1
 UniProt Synonym Protein Names   
Episialin; CD_antigen: CD227Cleaved into the following 2 chains:Mucin-1 subunit alpha; MUC1-NT; MUC1-alpha; Mucin-1 subunit beta; MUC1-betaAlternative name(s):MUC1-CT
 UniProt Gene Name    Muc1 [Similar Products]
 UniProt Synonym Gene Names    Muc-1; MUC-1; MUC1-NT; MUC1-alpha; MUC1-beta [Similar Products]
 UniProt Entry Name    MUC1_MOUSE
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 UniProt Comments for EMA    MUC1: a large cell surface glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. Plays a role in adhesion and cell-cell interactions, metastasis and signaling. May provide a protective layer on epithelial surfaces. Direct or indirect interaction with actin cytoskeleton. Its cytoplasmic tail (MUC1CT) is involved in several signaling pathways, including those involving Ras, beta-catenin, p120 catenin, p53 and estrogen receptor alpha. MUC1CT also forms complexes with transcription factors, and then translocates to the nucleus by an unknown mechanism, where it is believed to influence the transcription of their target genes. MUC1CT has also been proposed to localize to mitochondrial membranes under conditions of genotoxic stress, where it attenuates the apoptotic pathway in response and confers resistance to apoptosis-inducing drugs. Aberrantly glycosylated forms expressed in human epithelial tumors, such as breast or ovarian cancer and also in non-epithelial tumor cells. Nine alternatively spliced isoforms have been described. Isoforms 5 and 9 are secreted. Isoform 7, expressed only in tumor cells, is a receptor and binds the secreted isoform 5. The binding induces the phosphorylation of the isoform 7, alters cellular morphology and initiates cell signaling. Can bind to GRB2 adapter protein.

Protein type: Actin-binding; Tumor suppressor; Nuclear receptor co-regulator; Membrane protein, integral; Motility/polarity/chemotaxis; Cell adhesion

Cellular Component: cell surface; membrane; cytoplasm; apical plasma membrane; integral to membrane; plasma membrane; nucleus
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 Research Articles on EMA    1. MUC1 overexpression in alveolar epithelial cells does not account for the anti-inflammatory effects of the NSAID, Tanshinone IIA, in the airway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with EMA elisa kitPathways associated with EMA elisa kit
 Reference Product  PubMed Publications
 Muc5b elisa kit  >133 publications with EMA and Muc5b
 Egfr elisa kit  >79 publications with EMA and Egfr
 Muc13 elisa kit  >14 publications with EMA and Muc13
 Muc15 elisa kit  >9 publications with EMA and Muc15
 Galnt6 elisa kit  >2 publications with EMA and Galnt6
 Products by Pathway  Pathway Diagram
 IL-7 Signaling Pathway antibodies  IL-7 Signaling Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 O-linked Glycosylation Of Mucins Pathway antibodies  O-linked Glycosylation Of Mucins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 T Cell Receptor Signaling Pathway antibodies  T Cell Receptor Signaling Pathway Diagram
 Termination Of O-glycan Biosynthesis Pathway antibodies  Termination Of O-glycan Biosynthesis Pathway Diagram
Diseases associated with EMA elisa kitOrgans/Tissues associated with EMA elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1906 publications with EMA and Neoplasms
 Carcinoma Antibodies  >1131 publications with EMA and Carcinoma
 Breast Neoplasms Antibodies  >592 publications with EMA and Breast Neoplasms
 Lung Diseases Antibodies  >437 publications with EMA and Lung Diseases
 Lung Neoplasms Antibodies  >196 publications with EMA and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >169 publications with EMA and Neoplasms, Experimental
 Ovarian Neoplasms Antibodies  >163 publications with EMA and Ovarian Neoplasms
 Disease Models, Animal Antibodies  >159 publications with EMA and Disease Models, Animal
 Pneumonia Antibodies  >131 publications with EMA and Pneumonia
 Inflammation Antibodies  >113 publications with EMA and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >506 publications with EMA and Lung
 Stomach Antibodies  >204 publications with EMA and Stomach
 Pancreas Antibodies  >198 publications with EMA and Pancreas
 Eye Antibodies  >97 publications with EMA and Eye
 Kidney Antibodies  >91 publications with EMA and Kidney
 Uterus Antibodies  >75 publications with EMA and Uterus
 Mammary Gland Antibodies  >50 publications with EMA and Mammary Gland
 Embryonic Tissue Antibodies  >38 publications with EMA and Embryonic Tissue
 Nasopharynx Antibodies  >2 publications with EMA and Nasopharynx
 Extraembryonic Tissue Antibodies  >1 publications with EMA and Extraembryonic Tissue
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