Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow HbA1c rightarrow Rabbit HbA1c  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • IGF-I (Igf1) Recombinant Protein
 • ACTA1 - ASMA Antibody
 • Staphylococcus Enterotoxin Type A Antibody
 • NE ELISA Kit
 • Actinin Alpha 1 (ACTN1) Recombinant Protein
 • CXCR4 Antibody
 • ADAMTS1 ELISA Kit
 • cross linked N-telopeptide of type I collagen, NTX ELISA Kit
 • Malondialdehyde (MDA) ELISA Kit
 • FASLG Recombinant Protein
 • HARS Recombinant Protein
 • C Reactive Protein (CRP) Antibody
 • anti-Goat IgG Fc Antibody
 • Glutaredoxin 2 (GLRX2) Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

HbA1c elisa kit :: Rabbit HbA1c ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2507985 HbA1c elisa kit
Unit / Price
48-Strip-Wells  /  $450 +1 FREE 8GB USB
96-Strip-Wells  /  $535 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,255 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HbA1c, ELISA Kit

★Popular Item★
 Also Known As   

Rabbit HbA1c(Glycosylated Hemoglobin/Hemoglobin A1c)ELISA Kit

 Product Gene Name   

HbA1c elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2507985 COA    COA PDF
 OMIM    140700
 3D Structure    ModBase 3D Structure for P69905
Section Bar
 Species Reactivity    Rabbit
Section Bar
 Specificity    This kit recognizes natural and recombinant Rabbit HbA1c. No significant cross-reactivity or interference between Rabbit HbA1c and analogues was observed.
Section Bar
 Samples    Serum, plasma and other biological fluids
 Assay Type    Quantitative Sandwich
 Detection Range    3.125-200ng/mL
 Sensitivity    1.875ng/mL
Section Bar
 Preparation and Storage    Store at 4 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HbA1c elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HbA1c purchase    MBS2507985 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the HbA1c, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 3.125-200ng/mL in biological research samples containing HbA1c, with an estimated sensitivity of 1.875ng/mL. The ELISA analytical biochemical technique of the MBS2507985 kit is based on HbA1c antibody-HbA1c antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HbA1c antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HbA1c. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
 

Product Description specifically for HbA1c elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Rabbit HbA1c concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to HbA1c. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for HbA1c and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain HbA1c, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of HbA1c. You can calculate the concentration of HbA1c in the samples by comparing the OD of the samples to the standard curve.
Sample Manual Insert of MBS2507985. Click to request current manual
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for HbA1c. It may not necessarily be applicable to this product.
 NCBI GI #    4504347
 NCBI GeneID    3039
 NCBI Accession #    NP_000549.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000558.4 [Other Products]
Section Bar
 UniProt Primary Accession #    P69905 [Other Products]
 UniProt Secondary Accession #    P01922; Q1HDT5; Q3MIF5; Q53F97; Q96KF1; Q9NYR7; Q9UCM0 [Other Products]
 UniProt Related Accession #    P69905 [Other Products]
 Molecular Weight    15,258 Da
Table BarTOPTable Bar
 NCBI Official Full Name    hemoglobin subunit alpha
 NCBI Official Synonym Full Names    hemoglobin, alpha 1
 NCBI Official Symbol    HBA1 [Similar Products]
 NCBI Official Synonym Symbols   
HBH; HBA-T3
[Similar Products]
 NCBI Protein Information    hemoglobin subunit alpha; alpha one globin; alpha-1 globin; alpha-1-globin; alpha-2 globin chain; alpha-globin; delta globin; hemoglobin alpha 1 globin chain; hemoglobin alpha chain; hemoglobin alpha-1 chain
 UniProt Protein Name    Hemoglobin subunit alpha
 UniProt Synonym Protein Names   
Alpha-globin; Hemoglobin alpha chain
 UniProt Gene Name    HBA1 [Similar Products]
 UniProt Entry Name    HBA_HUMAN
Section Bar
 NCBI Summary for HbA1c    The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for HbA1c    HBA1: Involved in oxygen transport from the lung to the various peripheral tissues. Defects in HBA1 may be a cause of Heinz body anemias (HEIBAN). This is a form of non-spherocytic hemolytic anemia of Dacie type 1. After splenectomy, which has little benefit, basophilic inclusions called Heinz bodies are demonstrable in the erythrocytes. Before splenectomy, diffuse or punctate basophilia may be evident. Most of these cases are probably instances of hemoglobinopathy. The hemoglobin demonstrates heat lability. Heinz bodies are observed also with the Ivemark syndrome (asplenia with cardiovascular anomalies) and with glutathione peroxidase deficiency. Defects in HBA1 are the cause of alpha-thalassemia (A- THAL). The thalassemias are the most common monogenic diseases and occur mostly in Mediterranean and Southeast Asian populations. The hallmark of alpha-thalassemia is an imbalance in globin-chain production in the adult HbA molecule. The level of alpha chain production can range from none to very nearly normal levels. Deletion of both copies of each of the two alpha-globin genes causes alpha(0)-thalassemia, also known as homozygous alpha thalassemia. Due to the complete absence of alpha chains, the predominant fetal hemoglobin is a tetramer of gamma-chains (Bart hemoglobin) that has essentially no oxygen carrying capacity. This causes oxygen starvation in the fetal tissues leading to prenatal lethality or early neonatal death. The loss of three alpha genes results in high levels of a tetramer of four beta chains (hemoglobin H), causing a severe and life-threatening anemia known as hemoglobin H disease. Untreated, most patients die in childhood or early adolescence. The loss of two alpha genes results in mild alpha-thalassemia, also known as heterozygous alpha-thalassemia. Affected individuals have small red cells and a mild anemia (microcytosis). If three of the four alpha-globin genes are functional, individuals are completely asymptomatic. Some rare forms of alpha-thalassemia are due to point mutations (non- deletional alpha-thalassemia). The thalassemic phenotype is due to unstable globin alpha chains that are rapidly catabolized prior to formation of the alpha-beta heterotetramers. Alpha(0)-thalassemia is associated with non-immune hydrops fetalis, a generalized edema of the fetus with fluid accumulation in the body cavities due to non-immune causes. Non- immune hydrops fetalis is not a diagnosis in itself but a symptom, a feature of many genetic disorders, and the end-stage of a wide variety of disorders. Defects in HBA1 are the cause of hemoglobin H disease (HBH). HBH is a form of alpha-thalassemia due to the loss of three alpha genes. This results in high levels of a tetramer of four beta chains (hemoglobin H), causing a severe and life-threatening anemia. Untreated, most patients die in childhood or early adolescence. Belongs to the globin family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: membrane; hemoglobin complex; extracellular region; cytosol

Molecular Function: haptoglobin binding; protein binding; peroxidase activity; iron ion binding; heme binding; oxygen binding; oxygen transporter activity

Biological Process: receptor-mediated endocytosis; response to hydrogen peroxide; hydrogen peroxide catabolic process; protein heterooligomerization; bicarbonate transport; oxygen transport

Disease: Hemoglobin H Disease; Heinz Body Anemias; Alpha-thalassemia
Table BarTOPTable Bar
 Research Articles on HbA1c    1. High HbA1c levels are associated with high grade prostate cancer.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with HbA1c elisa kitPathways associated with HbA1c elisa kit
 Reference Product  PubMed Publications
 HBB elisa kit  >18 publications with HbA1c and HBB
 HBD elisa kit  >14 publications with HbA1c and HBD
 CD34 elisa kit  >13 publications with HbA1c and CD34
 CD38 elisa kit  >2 publications with HbA1c and CD38
 HBG2 elisa kit  >2 publications with HbA1c and HBG2
 HBE1 elisa kit  >1 publications with HbA1c and HBE1
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Erythrocytes Take Up Carbon Dioxide And Release Oxygen Pathway antibodies  Erythrocytes Take Up Carbon Dioxide And Release Oxygen Pathway Diagram
 Erythrocytes Take Up Oxygen And Release Carbon Dioxide Pathway antibodies  Erythrocytes Take Up Oxygen And Release Carbon Dioxide Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 O2/CO2 Exchange In Erythrocytes Pathway antibodies  O2/CO2 Exchange In Erythrocytes Pathway Diagram
 Scavenging Of Heme From Plasma Pathway antibodies  Scavenging Of Heme From Plasma Pathway Diagram
Diseases associated with HbA1c elisa kitOrgans/Tissues associated with HbA1c elisa kit
 Disease Name  Pubmed Publications
 Diabetes Mellitus, Type 2 Antibodies  >10656 publications with HbA1c and Diabetes Mellitus, Type 2
 Hyperglycemia Antibodies  >2972 publications with HbA1c and Hyperglycemia
 Insulin Resistance Antibodies  >1941 publications with HbA1c and Insulin Resistance
 Kidney Diseases Antibodies  >1688 publications with HbA1c and Kidney Diseases
 Hypertension Antibodies  >1644 publications with HbA1c and Hypertension
 Heart Diseases Antibodies  >1245 publications with HbA1c and Heart Diseases
 Weight Loss Antibodies  >783 publications with HbA1c and Weight Loss
 Disease Models, Animal Antibodies  >720 publications with HbA1c and Disease Models, Animal
 Atherosclerosis Antibodies  >610 publications with HbA1c and Atherosclerosis
 Glucose Intolerance Antibodies  >548 publications with HbA1c and Glucose Intolerance
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >20728 publications with HbA1c and Blood
 Heart Antibodies  >1371 publications with HbA1c and Heart
 Kidney Antibodies  >1234 publications with HbA1c and Kidney
 Pancreas Antibodies  >965 publications with HbA1c and Pancreas
 Eye Antibodies  >685 publications with HbA1c and Eye
 Liver Antibodies  >638 publications with HbA1c and Liver
 Muscle Antibodies  >505 publications with HbA1c and Muscle
 Nerve Antibodies  >340 publications with HbA1c and Nerve
 Bone Antibodies  >284 publications with HbA1c and Bone
 Adipose Tissue Antibodies  >283 publications with HbA1c and Adipose Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions