AAC12732.1
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UniProt Secondary Accession #
Molecular Weight
66,646 Da
NCBI Official Full Name
interleukin-16
UniProt Protein Name
Pro-interleukin-16
UniProt Synonym Protein Names
Lymphocyte chemoattractant factor; LCF
UniProt Synonym Gene Names
UniProt Entry Name
IL16_HUMAN
UniProt Comments for IL-16
IL16: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. 3 isoforms of the human protein are produced by alternative promoter.
Protein type: DNA-binding; Motility/polarity/chemotaxis; Cytokine
Chromosomal Location of Human Ortholog: 15q26.3
Cellular Component: extracellular space; cytoplasm; plasma membrane; nucleus
Molecular Function: cytokine activity
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; viral reproduction; leukocyte chemotaxis; immune response; induction of positive chemotaxis
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