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IL21 elisa kit :: Rabbit Interleukin 21 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS024718 IL21 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 21 (IL21), ELISA Kit

 Also Known As   

Rabbit Interleukin 21 ELISA Kit

 Product Gene Name   

IL21 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 4; NC_000004.11 (123533783..123542212, complement). Location: 4q26-q27
 OMIM    605384
 3D Structure    ModBase 3D Structure for Q9HBE4
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 Species Reactivity    Rabbit
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL21 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL21 purchase    MBS024718 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 21 (IL21) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IL21. The ELISA analytical biochemical technique of the MBS024718 kit is based on IL21 antibody-IL21 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL21 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL21. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for IL21. It may not necessarily be applicable to this product.
 NCBI GI #    333033767
 NCBI GeneID    59067
 NCBI Accession #    NP_001193935.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001207006.2 [Other Products]
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 UniProt Primary Accession #    Q9HBE4 [Other Products]
 UniProt Secondary Accession #    A5J0L4 [Other Products]
 UniProt Related Accession #    Q9HBE4 [Other Products]
 Molecular Weight    17,923 Da
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 NCBI Official Full Name    interleukin-21 isoform 2
 NCBI Official Synonym Full Names    interleukin 21
 NCBI Official Symbol    IL21 [Similar Products]
 NCBI Official Synonym Symbols   
Za11; IL-21
[Similar Products]
 NCBI Protein Information    interleukin-21; interleukin-21 isoform
 UniProt Protein Name    Interleukin-21
 UniProt Synonym Protein Names   
Za11
 Protein Family    Interleukin
 UniProt Gene Name    IL21 [Similar Products]
 UniProt Synonym Gene Names    IL-21 [Similar Products]
 UniProt Entry Name    IL21_HUMAN
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 NCBI Summary for IL21    This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
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 UniProt Comments for IL21    IL21: Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. Belongs to the IL-15/IL-21 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Cytokine; Secreted; Cell development/differentiation; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q26-q27

Cellular Component: extracellular space

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interleukin-2 receptor binding; cytokine activity

Biological Process: positive regulation of interleukin-17 production; positive regulation of natural killer cell cytokine production; cell maturation; signal transduction; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of interleukin-10 production; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of natural killer cell differentiation; positive regulation of tissue remodeling; positive regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of cell proliferation; positive regulation of B cell proliferation; positive regulation of T cell proliferation; immune response; positive regulation of interferon-gamma biosynthetic process; positive regulation of inflammatory response

Disease: Immunodeficiency, Common Variable, 11
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 Research Articles on IL21    1. Secreted IL-21 isoform also has less signaling activity than IL-21.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL21 elisa kitPathways associated with IL21 elisa kit
 Reference Product  PubMed Publications
 IL21R elisa kit  >299 publications with IL21 and IL21R
 STAT3 elisa kit  >97 publications with IL21 and STAT3
 IL15 elisa kit  >72 publications with IL21 and IL15
 IL4 elisa kit  >10 publications with IL21 and IL4
 IL13 elisa kit  >4 publications with IL21 and IL13
 IL7 elisa kit  >3 publications with IL21 and IL7
 IL9 elisa kit  >2 publications with IL21 and IL9
 NFATC2 elisa kit  >1 publications with IL21 and NFATC2
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Inflammatory Bowel Disease Pathway antibodies  Inflammatory Bowel Disease Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
Diseases associated with IL21 elisa kitOrgans/Tissues associated with IL21 elisa kit
 Disease Name  Pubmed Publications
 Autoimmune Diseases Antibodies  >202 publications with IL21 and Autoimmune Diseases
 Inflammation Antibodies  >129 publications with IL21 and Inflammation
 Skin Diseases Antibodies  >55 publications with IL21 and Skin Diseases
 Lupus Erythematosus, Systemic Antibodies  >51 publications with IL21 and Lupus Erythematosus, Systemic
 Necrosis Antibodies  >47 publications with IL21 and Necrosis
 Celiac Disease Antibodies  >29 publications with IL21 and Celiac Disease
 Liver Diseases Antibodies  >25 publications with IL21 and Liver Diseases
 Kidney Diseases Antibodies  >24 publications with IL21 and Kidney Diseases
 Hepatitis Antibodies  >23 publications with IL21 and Hepatitis
 Hypersensitivity Antibodies  >19 publications with IL21 and Hypersensitivity
 Organ/Tissue Name  Pubmed Publications
 Uncharacterized Tissue Antibodies  >1 publications with IL21 and Uncharacterized Tissue
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