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IL-6 elisa kit :: Rabbit Interleukin 6 (IL-6) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2602269
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $300 +1 FREE 8GB USB
96-Strip-Wells  /  $475 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 6 (IL-6), ELISA Kit

★Popular Item★
 Also Known As   

Rabbit Interleukin 6 (IL-6) ELISA Kit

 Product Gene Name   

IL-6 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    604302
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 Species Reactivity    Rabbit
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 Specificity    No cross-reaction with other factors.
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 Samples    Serum, plasma or cell culture supernatant and organizations in the natural and recombinant IL-6 concentration
 Assay Type    Sandwich
 Detection Range    1000 pg/ml-15.6 pg/ml
 Sensitivity    5 pg/ml.
 Intra-assay Precision    ? 8%
 Inter-assay Precision    ? 12%
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL-6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL-6 purchase    MBS2602269 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 6 (IL-6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1000 pg/ml-15.6 pg/ml in biological research samples containing IL-6, with an estimated sensitivity of 5 pg/ml. The ELISA analytical biochemical technique of the MBS2602269 kit is based on IL-6 antibody-IL-6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL-6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL-6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma or cell culture supernatant and organizations in the natural and recombinant IL-6 concentration. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for IL-6 elisa kit

   Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Rabbit IL-6 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
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 Typical Testing Data/Standard Curve (for reference only) of IL-6 elisa kit    IL-6 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2602269. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IL-6. It may not necessarily be applicable to this product.
 NCBI GI #    10834984
 NCBI GeneID    3569
 NCBI Accession #    NP_000591.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000600.3 [Other Products]
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 UniProt Secondary Accession #    Q9UCU2; Q9UCU3; Q9UCU4 [Other Products]
 UniProt Related Accession #    P05231 [Other Products]
 Molecular Weight    23,718 Da
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 NCBI Official Full Name    interleukin-6
 NCBI Official Synonym Full Names    interleukin 6
 NCBI Official Symbol    IL6 [Similar Products]
 NCBI Official Synonym Symbols   
HGF; HSF; BSF2; IL-6; IFNB2
[Similar Products]
 NCBI Protein Information    interleukin-6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; interferon, beta 2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2; B-cell differentiation factor
 UniProt Protein Name    Interleukin-6
 UniProt Synonym Protein Names   
B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2
 UniProt Gene Name    IL6 [Similar Products]
 UniProt Synonym Gene Names    IFNB2; IL-6; BSF-2; CDF; IFN-beta-2 [Similar Products]
 UniProt Entry Name    IL6_HUMAN
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 NCBI Summary for IL-6    This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]
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 UniProt Comments for IL-6    IL6: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. Genetic variations in IL6 are associated with susceptibility to rheumatoid arthritis systemic juvenile (RASJ). An inflammatory articular disorder with systemic- onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis. A IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in HIV-infected men. Belongs to the IL-6 superfamily.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7p21

Cellular Component: extracellular space; cytoplasm; extracellular region; interleukin-6 receptor complex; external side of plasma membrane

Molecular Function: protein binding; interleukin-6 receptor binding; growth factor activity; cytokine activity

Biological Process: positive regulation of nitric oxide biosynthetic process; positive regulation of apoptosis; positive regulation of transcription, DNA-dependent; negative regulation of collagen biosynthetic process; response to glucocorticoid stimulus; negative regulation of cytokine secretion; positive regulation of JAK-STAT cascade; positive regulation of leukocyte chemotaxis; bone remodeling; glucose homeostasis; response to caffeine; activation of NF-kappaB transcription factor; positive regulation of tyrosine phosphorylation of Stat3 protein; muscle maintenance; response to antibiotic; monocyte chemotaxis; regulation of cell shape; positive regulation of T-helper 2 cell differentiation; positive regulation of acute inflammatory response; negative regulation of gluconeogenesis; acute-phase response; positive regulation of T cell proliferation; cell growth; response to electrical stimulus; defense response to virus; neurite development; response to drug; platelet activation; positive regulation of protein import into nucleus, translocation; positive regulation of interleukin-6 production; negative regulation of fat cell differentiation; defense response to protozoan; response to amino acid stimulus; positive regulation of chemokine production; defense response to Gram-positive bacterium; positive regulation of peptidyl-tyrosine phosphorylation; cell redox homeostasis; response to heat; positive regulation of B cell activation; neutrophil apoptosis; negative regulation of protein kinase activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; response to calcium ion; positive regulation of epithelial cell proliferation; negative regulation of apoptosis; negative regulation of muscle development; positive regulation of translation; negative regulation of hormone secretion; positive regulation of smooth muscle cell proliferation; neutrophil mediated immunity; regulation of circadian sleep/wake cycle, non-REM sleep; negative regulation of caspase activity; defense response to Gram-negative bacterium; response to insulin stimulus; negative regulation of cell proliferation; positive regulation of MAPKKK cascade; response to peptidoglycan; positive regulation of cell proliferation; hepatic immune response; inflammatory response; negative regulation of chemokine biosynthetic process; aging; response to nutrient levels; cytokine and chemokine mediated signaling pathway; positive regulation of immunoglobulin secretion; endocrine pancreas development; positive regulation of peptidyl-serine phosphorylation; regulation of angiogenesis; humoral immune response; positive regulation of osteoblast differentiation; positive regulation of protein kinase B signaling cascade; response to cold; positive regulation of neuron differentiation; positive regulation of DNA replication; positive regulation of transmission of nerve impulse

Disease: Rheumatoid Arthritis, Systemic Juvenile; Arteriovenous Malformations Of The Brain; Kaposi Sarcoma, Susceptibility To; Inflammatory Bowel Disease 1
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 Research Articles on IL-6    1. IL-6 modulates the expression of Sox2.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL-6 elisa kitPathways associated with IL-6 elisa kit
 Reference Product  PubMed Publications
 JUN elisa kit  >574 publications with IL-6 and JUN
 STAT3 elisa kit  >344 publications with IL-6 and STAT3
 IL1B elisa kit  >255 publications with IL-6 and IL1B
 IL17A elisa kit  >111 publications with IL-6 and IL17A
 IL6R elisa kit  >108 publications with IL-6 and IL6R
 STAT1 elisa kit  >59 publications with IL-6 and STAT1
 JAK2 elisa kit  >59 publications with IL-6 and JAK2
 SOCS3 elisa kit  >51 publications with IL-6 and SOCS3
 IL6ST elisa kit  >44 publications with IL-6 and IL6ST
 FOS elisa kit  >41 publications with IL-6 and FOS
 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Cellular Senescence Pathway antibodies  Cellular Senescence Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
Diseases associated with IL-6 elisa kitOrgans/Tissues associated with IL-6 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2184 publications with IL-6 and Inflammation
 Necrosis Antibodies  >1588 publications with IL-6 and Necrosis
 Autoimmune Diseases Antibodies  >417 publications with IL-6 and Autoimmune Diseases
 Skin Diseases Antibodies  >273 publications with IL-6 and Skin Diseases
 Arthritis, Rheumatoid Antibodies  >251 publications with IL-6 and Arthritis, Rheumatoid
 Atherosclerosis Antibodies  >224 publications with IL-6 and Atherosclerosis
 Myocardial Ischemia Antibodies  >216 publications with IL-6 and Myocardial Ischemia
 Ischemia Antibodies  >115 publications with IL-6 and Ischemia
 Hypersensitivity Antibodies  >99 publications with IL-6 and Hypersensitivity
 Myocardial Infarction Antibodies  >98 publications with IL-6 and Myocardial Infarction
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2816 publications with IL-6 and Blood
 Vascular Antibodies  >616 publications with IL-6 and Vascular
 Bone Antibodies  >382 publications with IL-6 and Bone
 Lung Antibodies  >367 publications with IL-6 and Lung
 Brain Antibodies  >336 publications with IL-6 and Brain
 Muscle Antibodies  >275 publications with IL-6 and Muscle
 Kidney Antibodies  >251 publications with IL-6 and Kidney
 Connective Tissue Antibodies  >190 publications with IL-6 and Connective Tissue
 Skin Antibodies  >176 publications with IL-6 and Skin
 Eye Antibodies  >117 publications with IL-6 and Eye
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