NP_001070960.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
32,019 Da
NCBI Official Full Name
kallikrein-5 preproprotein
NCBI Official Synonym Full Names
kallikrein-related peptidase 5
NCBI Protein Information
kallikrein-5; kallikrein 5; kallikrein-like protein 2; stratum corneum tryptic enzyme
UniProt Protein Name
Kallikrein-5
UniProt Synonym Protein Names
Kallikrein-like protein 2; KLK-L2; Stratum corneum tryptic enzyme
UniProt Synonym Gene Names
UniProt Entry Name
KLK5_HUMAN
NCBI Summary for KLK5
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
UniProt Comments for KLK5
KLK5: May be involved in desquamation. Belongs to the peptidase S1 family. Kallikrein subfamily.
Protein type: Secreted, signal peptide; EC 3.4.21.-; Secreted; Protease
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: extracellular space
Molecular Function: peptidase activity; protein binding; serine-type peptidase activity; serine-type endopeptidase activity
Biological Process: epidermis development; positive regulation of G-protein coupled receptor protein signaling pathway; proteolysis
Research Articles on KLK5
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Products associated with KLK5 elisa kit
Diseases associated with KLK5 elisa kit
Organs/Tissues associated with KLK5 elisa kit
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