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L1CAM elisa kit :: Rabbit L1-Cell Adhesion Molecule ELISA Kit

Scan QR to view Datasheet Catalog #    MBS748437 L1CAM elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

L1-Cell Adhesion Molecule (L1CAM), ELISA Kit

 Also Known As   

Rabbit L1-Cell Adhesion Molecule ELISA Kit

 Product Gene Name   

L1CAM elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    308840
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 Species Reactivity    Rabbit
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of L1CAM elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for L1CAM purchase    MBS748437 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the L1-Cell Adhesion Molecule (L1CAM) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing L1CAM. The ELISA analytical biochemical technique of the MBS748437 kit is based on L1CAM antibody-L1CAM antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect L1CAM antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, L1CAM. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for L1CAM elisa kit    Cell Biology
NCBI/Uniprot data below describe general gene information for L1CAM. It may not necessarily be applicable to this product.
 NCBI GI #    19388023
 NCBI GeneID    3897
 NCBI Accession #    AAH25843.1 [Other Products]
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 UniProt Secondary Accession #    Q8TA87; A0AV65; A4ZYW4; B2RMU7; G3XAF4 [Other Products]
 UniProt Related Accession #    P32004 [Other Products]
 Molecular Weight    138,908 Da
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 NCBI Official Full Name    L1CAM protein, partial
 NCBI Official Synonym Full Names    L1 cell adhesion molecule
 NCBI Official Symbol    L1CAM [Similar Products]
 NCBI Official Synonym Symbols   
S10; HSAS; MASA; MIC5; SPG1; CAML1; CD171; HSAS1; N-CAML1; NCAM-L1; N-CAM-L1
[Similar Products]
 NCBI Protein Information    neural cell adhesion molecule L1; antigen identified by monoclonal antibody R1
 UniProt Protein Name    Neural cell adhesion molecule L1
 UniProt Synonym Protein Names   
CD_antigen: CD171
 Protein Family    Neural cell adhesion molecule
 UniProt Gene Name    L1CAM [Similar Products]
 UniProt Synonym Gene Names    CAML1; MIC5; N-CAM-L1; NCAM-L1 [Similar Products]
 UniProt Entry Name    L1CAM_HUMAN
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 NCBI Summary for L1CAM    The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013]
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 UniProt Comments for L1CAM    NCAM-L1: cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons. Two splice-variant isoforms have been described.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: presynaptic membrane; cell surface; focal adhesion; integral to membrane; plasma membrane; terminal button; external side of plasma membrane

Molecular Function: integrin binding; identical protein binding; protein self-association; sialic acid binding

Biological Process: heterophilic cell adhesion; axon guidance; nervous system development; leukocyte adhesion; cell surface receptor linked signal transduction; homotypic cell-cell adhesion; cell-cell adhesion mediated by integrin; positive regulation of cell-cell adhesion; positive regulation of calcium-mediated signaling; homophilic cell adhesion; blood coagulation; chemotaxis; cell adhesion; leukocyte migration

Disease: Hydrocephalus Due To Congenital Stenosis Of Aqueduct Of Sylvius; Corpus Callosum, Partial Agenesis Of, X-linked; Masa Syndrome
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 Research Articles on L1CAM    1. Human pathological H210Q, R184Q and Y1070C, but not the E309K and L120V L1CAM mutations affect outside-in signaling via the FIGQY Ankyrin binding domain which is required for synapse formation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with L1CAM elisa kitPathways associated with L1CAM elisa kit
 Reference Product  PubMed Publications
 NCAM1 elisa kit  >1470 publications with L1CAM and NCAM1
 CNTN2 elisa kit  >16 publications with L1CAM and CNTN2
 NCAN elisa kit  >10 publications with L1CAM and NCAN
 ANK2 elisa kit  >7 publications with L1CAM and ANK2
 RANBP9 elisa kit  >1 publications with L1CAM and RANBP9
 CNTN1 elisa kit  >1 publications with L1CAM and CNTN1
 NUMB elisa kit  >1 publications with L1CAM and NUMB
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Basigin Interactions Pathway antibodies  Basigin Interactions Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Interaction Between L1 And Ankyrins Pathway antibodies  Interaction Between L1 And Ankyrins Pathway Diagram
Diseases associated with L1CAM elisa kitOrgans/Tissues associated with L1CAM elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >329 publications with L1CAM and Nervous System Diseases
 Brain Diseases Antibodies  >211 publications with L1CAM and Brain Diseases
 Disease Models, Animal Antibodies  >83 publications with L1CAM and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >53 publications with L1CAM and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >50 publications with L1CAM and Adenocarcinoma
 Ovarian Neoplasms Antibodies  >34 publications with L1CAM and Ovarian Neoplasms
 Cardiovascular Diseases Antibodies  >28 publications with L1CAM and Cardiovascular Diseases
 Aphasia Antibodies  >23 publications with L1CAM and Aphasia
 Neoplasms, Experimental Antibodies  >22 publications with L1CAM and Neoplasms, Experimental
 Hirschsprung Disease Antibodies  >21 publications with L1CAM and Hirschsprung Disease
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >825 publications with L1CAM and Brain
 Nerve Antibodies  >451 publications with L1CAM and Nerve
 Embryonic Tissue Antibodies  >108 publications with L1CAM and Embryonic Tissue
 Ganglia Antibodies  >64 publications with L1CAM and Ganglia
 Eye Antibodies  >58 publications with L1CAM and Eye
 Muscle Antibodies  >46 publications with L1CAM and Muscle
 Kidney Antibodies  >38 publications with L1CAM and Kidney
 Skin Antibodies  >30 publications with L1CAM and Skin
 Lung Antibodies  >29 publications with L1CAM and Lung
 Liver Antibodies  >29 publications with L1CAM and Liver
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