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HLA-B elisa kit :: Rabbit Leukocyte Antigen B ELISA Kit

Scan QR to view Datasheet Catalog #    MBS009254 HLA-B elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Leukocyte Antigen B (HLA-B), ELISA Kit

 Also Known As   

Rabbit Leukocyte Antigen B ELISA Kit

 Product Gene Name   

HLA-B elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 6; NC_000006.11 (31321649..31324989, complement). Location: 6p21.3
 OMIM    142830
 3D Structure    ModBase 3D Structure for P01889
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 Species Reactivity    Rabbit
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HLA-B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HLA-B purchase    MBS009254 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Leukocyte Antigen B (HLA-B) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HLA-B. The ELISA analytical biochemical technique of the MBS009254 kit is based on HLA-B antibody-HLA-B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HLA-B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HLA-B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for HLA-B. It may not necessarily be applicable to this product.
 NCBI GI #    2341083
 NCBI GeneID    3106
 NCBI Accession #    AAC29503.1 [Other Products]
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 UniProt Primary Accession #    P01889 [Other Products]
 UniProt Secondary Accession #    Q29638; Q29681; Q29854; Q29861; Q31613; Q5SRJ2; Q9GIX1; Q9TP95 [Other Products]
 UniProt Related Accession #    P01889; P03989; P10319; P18463; P18464; P18465; P30460; P30461; P30462; P30464 [Other Products]
 Molecular Weight    40,460 Da
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 NCBI Official Full Name    HLA-B, partial
 NCBI Official Synonym Full Names    major histocompatibility complex, class I, B
 NCBI Official Symbol    HLA-B [Similar Products]
 NCBI Official Synonym Symbols   
AS; HLAB; SPDA1
[Similar Products]
 NCBI Protein Information    major histocompatibility complex, class I, B; lymphocyte antigen; MHC class I antigen SHCHA; MHC Class I HLA heavy chain; MHC class I antigen GN00104; leukocyte antigen class I-B; MHC HLA-B cell surface glycoprotein; MHC HLA-B transmembrane glycoprotein; MHC class I antigen HLA-B heavy chain; HLA class I histocompatibility antigen, B alpha chain
 UniProt Protein Name    HLA class I histocompatibility antigen, B-7 alpha chain
 UniProt Synonym Protein Names   
MHC class I antigen B*7
 Protein Family    HLA class I histocompatibility antigen
 UniProt Gene Name    HLA-B [Similar Products]
 UniProt Synonym Gene Names    HLAB [Similar Products]
 UniProt Entry Name    1B07_HUMAN
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 NCBI Summary for HLA-B    HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for HLA-B    HLAB iso7: Involved in the presentation of foreign antigens to the immune system. Belongs to the MHC class I family.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: Golgi membrane; Golgi apparatus; phagocytic vesicle membrane; cell surface; membrane; early endosome membrane; integral to plasma membrane; endoplasmic reticulum; plasma membrane; integral to membrane; MHC class I protein complex

Molecular Function: peptide antigen binding; chaperone binding; TAP binding; receptor binding

Biological Process: regulation of immune response; regulation of interleukin-12 production; detection of bacterium; viral reproduction; positive regulation of T cell mediated cytotoxicity; cytokine and chemokine mediated signaling pathway; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; defense response; protection from natural killer cell mediated cytotoxicity; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; regulation of T cell anergy; regulation of interleukin-6 production; antigen processing and presentation of exogenous peptide antigen via MHC class I; innate immune response; immune response
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 Research Articles on HLA-B    1. different HLA loci(HLA-A and HLA-B) are differentially regulated during differentiation of stem cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with HLA-B elisa kitDiseases associated with HLA-B elisa kit
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway antibodies  Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing-Cross Presentation Pathway antibodies  Antigen Processing-Cross Presentation Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Disease Name  Pubmed Publications
 Spondylitis, Ankylosing Antibodies  >1547 publications with HLA-B and Spondylitis, Ankylosing
 Genetic Predisposition to Disease Antibodies  >895 publications with HLA-B and Genetic Predisposition to Disease
 HIV Infections Antibodies  >556 publications with HLA-B and HIV Infections
 Nervous System Diseases Antibodies  >544 publications with HLA-B and Nervous System Diseases
 Necrosis Antibodies  >365 publications with HLA-B and Necrosis
 Behcet Syndrome Antibodies  >316 publications with HLA-B and Behcet Syndrome
 Drug Hypersensitivity Antibodies  >273 publications with HLA-B and Drug Hypersensitivity
 Liver Diseases Antibodies  >226 publications with HLA-B and Liver Diseases
 Lymphatic Diseases Antibodies  >215 publications with HLA-B and Lymphatic Diseases
 Kidney Diseases Antibodies  >208 publications with HLA-B and Kidney Diseases
Organs/Tissues associated with HLA-B elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3962 publications with HLA-B and Blood
 Bone Antibodies  >655 publications with HLA-B and Bone
 Kidney Antibodies  >627 publications with HLA-B and Kidney
 Bone Marrow Antibodies  >449 publications with HLA-B and Bone Marrow
 Skin Antibodies  >351 publications with HLA-B and Skin
 Eye Antibodies  >259 publications with HLA-B and Eye
 Liver Antibodies  >235 publications with HLA-B and Liver
 Heart Antibodies  >188 publications with HLA-B and Heart
 Lung Antibodies  >160 publications with HLA-B and Lung
 Vascular Antibodies  >137 publications with HLA-B and Vascular
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