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LXA4 elisa kit :: Rabbit Lipoxin A4 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS748043
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Lipoxin A4 (LXA4), ELISA Kit

★Popular Item★
 Also Known As   

Rabbit Lipoxin A4 ELISA Kit

 Product Gene Name   

LXA4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    136538
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 Species Reactivity    Rabbit
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    5.0-100ng/mL
 Sensitivity    1.0ng/mL
 Intended Uses    This LXA4 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Rabbit LXA4. This ELISA kit for research use only, not for therapeutic or diagnostic applications
 !Intended Uses    This LXA4 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Rabbit LXA4. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of LXA4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for LXA4 purchase    MBS748043 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Lipoxin A4 (LXA4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 5.0-100ng/mL in biological research samples containing LXA4, with an estimated sensitivity of 1.0ng/mL. The ELISA analytical biochemical technique of the MBS748043 kit is based on LXA4 antibody-LXA4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LXA4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LXA4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for LXA4 elisa kit

   Principle of the Assay: LXA4 ELISA kit applies the competitive enzyme immunoassay technique utilizing a monoclonal anti-LXA4 antibody and an LXA4-HRP conjugate. The assay sample and buffer are incubated together with LXA4-HRP conjugate in pre-coated plate for one hour. After the incubation period, the wells are decanted and washed five times. The wells are then incubated with a substrate for HRP enzyme. The product of the enzyme-substrate reaction forms a blue colored complex. Finally, a stop solution is added to stop the reaction, which will then turn the solution yellow. The intensity of color is measured spectrophotometrically at 450nm in a microplate reader. The intensity of the color is inversely proportional to the LXA4 concentration since LXA4 from samples and LXA4-HRP conjugate compete for the anti-LXA4 antibody binding site. Since the number of sites is limited, as more sites are occupied by LXA4 from the sample, fewer sites are left to bind LXA4-HRP conjugate. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The LXA4 concentration in each sample is interpolated from this standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of LXA4 elisa kit    LXA4 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS748043. Click to request current manual
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NCBI/Uniprot data below describe general gene information for LXA4. It may not necessarily be applicable to this product.
 NCBI GI #    1916076
 NCBI GeneID    2358
 NCBI Accession #    AAB51133.1 [Other Products]
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 UniProt Secondary Accession #    A8K3E2 [Other Products]
 UniProt Related Accession #    P25090; AAB23104 [Other Products]
 Molecular Weight    38,964 Da
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 NCBI Official Full Name    lipoxin A4 receptor
 NCBI Official Synonym Full Names    formyl peptide receptor 2
 NCBI Official Symbol    FPR2 [Similar Products]
 NCBI Official Synonym Symbols   
ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II
[Similar Products]
 NCBI Protein Information    N-formyl peptide receptor 2; RFP; FMLP-R-I; LXA4 receptor; FMLP-related receptor I; formyl peptide receptor-like 1; lipoxin A4 receptor (formyl peptide receptor related)
 UniProt Protein Name    N-formyl peptide receptor 2
 UniProt Synonym Protein Names   
FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
 UniProt Gene Name    FPR2 [Similar Products]
 UniProt Synonym Gene Names    FPRH1; FPRL1; LXA4R; FMLP-R-I; LXA4 receptor [Similar Products]
 UniProt Entry Name    FPR2_HUMAN
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 UniProt Comments for LXA4    FPR2: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Motility/polarity/chemotaxis; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19q13.3-q13.4

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; N-formyl peptide receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; cell motility; inflammatory response; chemotaxis; cell adhesion
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 Research Articles on LXA4    1. We also found that human mast cells expressed the N-formyl-peptide receptor 1 (FPRL1) receptor and FPRL1-specific inhibitor affected pleurocidin-mediated activation of mast cell.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LXA4 elisa kitPathways associated with LXA4 elisa kit
 Reference Product  PubMed Publications
 FPR1 elisa kit  >67 publications with LXA4 and FPR1
 ANXA1 elisa kit  >22 publications with LXA4 and ANXA1
 CXCR2 elisa kit  >5 publications with LXA4 and CXCR2
 CXCR1 elisa kit  >4 publications with LXA4 and CXCR1
 PLAUR elisa kit  >3 publications with LXA4 and PLAUR
 CCR1 elisa kit  >2 publications with LXA4 and CCR1
 APP elisa kit  >2 publications with LXA4 and APP
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway antibodies  Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with LXA4 elisa kitOrgans/Tissues associated with LXA4 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >176 publications with LXA4 and Inflammation
 Necrosis Antibodies  >29 publications with LXA4 and Necrosis
 Lung Diseases Antibodies  >23 publications with LXA4 and Lung Diseases
 Vascular Diseases Antibodies  >17 publications with LXA4 and Vascular Diseases
 Autoimmune Diseases Antibodies  >15 publications with LXA4 and Autoimmune Diseases
 Respiratory Hypersensitivity Antibodies  >8 publications with LXA4 and Respiratory Hypersensitivity
 Fibrosis Antibodies  >8 publications with LXA4 and Fibrosis
 Lung Injury Antibodies  >8 publications with LXA4 and Lung Injury
 Respiratory Tract Infections Antibodies  >6 publications with LXA4 and Respiratory Tract Infections
 Carcinoma Antibodies  >5 publications with LXA4 and Carcinoma
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >189 publications with LXA4 and Blood
 Lung Antibodies  >45 publications with LXA4 and Lung
 Kidney Antibodies  >13 publications with LXA4 and Kidney
 Bone Marrow Antibodies  >11 publications with LXA4 and Bone Marrow
 Spleen Antibodies  >8 publications with LXA4 and Spleen
 Connective Tissue Antibodies  >6 publications with LXA4 and Connective Tissue
 Heart Antibodies  >5 publications with LXA4 and Heart
 Placenta Antibodies  >3 publications with LXA4 and Placenta
 Testis Antibodies  >1 publications with LXA4 and Testis
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