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NOX2 elisa kit :: Rabbit Nicotinamide Adenine Dinucleotide Phosphate Oxidase 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS066572 NOX2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Nicotinamide Adenine Dinucleotide Phosphate Oxidase 2 (NOX2), ELISA Kit

 Also Known As   

Rabbit Nicotinamide Adenine Dinucleotide Phosphate Oxidase 2 ELISA Kit

 Product Gene Name   

NOX2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    233710
 3D Structure    ModBase 3D Structure for P19878
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 Species Reactivity    Rabbit
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of NOX2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NOX2 purchase    MBS066572 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Nicotinamide Adenine Dinucleotide Phosphate Oxidase 2 (NOX2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NOX2. The ELISA analytical biochemical technique of the MBS066572 kit is based on NOX2 antibody-NOX2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NOX2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NOX2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for NOX2. It may not necessarily be applicable to this product.
 NCBI GI #    1346669
 NCBI GeneID    4688
 NCBI Accession #    P19878.2 [Other Products]
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 UniProt Primary Accession #    P19878 [Other Products]
 UniProt Secondary Accession #    Q2PP06; Q8NFC7; Q9BV51; B2R6Q1; B4DKQ7; B4DQA7; E9PHJ2; E9PHX3 [Other Products]
 UniProt Related Accession #    P19878 [Other Products]
 Molecular Weight    59,762 Da
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 NCBI Official Full Name    Neutrophil cytosol factor 2
 NCBI Official Synonym Full Names    neutrophil cytosolic factor 2
 NCBI Official Symbol    NCF2 [Similar Products]
 NCBI Official Synonym Symbols   
NCF-2; NOXA2; P67PHOX; P67-PHOX
[Similar Products]
 NCBI Protein Information    neutrophil cytosol factor 2; NADPH oxidase activator 2; 67 kDa neutrophil oxidase factor; neutrophil NADPH oxidase factor 2; chronic granulomatous disease, autosomal 2; neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2)
 UniProt Protein Name    Neutrophil cytosol factor 2
 UniProt Synonym Protein Names   
67 kDa neutrophil oxidase factor; NADPH oxidase activator 2; Neutrophil NADPH oxidase factor 2; p67-phox
 UniProt Gene Name    NCF2 [Similar Products]
 UniProt Synonym Gene Names    NOXA2; P67PHOX; NCF-2 [Similar Products]
 UniProt Entry Name    NCF2_HUMAN
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 NCBI Summary for NOX2    This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]
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 UniProt Comments for NOX2    p67phox: NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). Interacts with SYTL1 and RAC1. Interacts with NCF4. May interact with NOXO1. Belongs to the NCF2/NOXA1 family.

Protein type: Oxidoreductase

Chromosomal Location of Human Ortholog: 1q25

Cellular Component: cytoplasm; acrosome; nucleolus; cytosol; NADPH oxidase complex

Molecular Function: protein C-terminus binding; protein binding; electron carrier activity; Rac GTPase binding

Biological Process: response to drug; respiratory burst; interaction with host; superoxide metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; response to lipopolysaccharide; cellular response to hormone stimulus; antigen processing and presentation of peptide antigen via MHC class I; response to hyperoxia; positive regulation of neuron apoptosis; response to glucose stimulus; innate immune response; cellular defense response; antigen processing and presentation of exogenous peptide antigen via MHC class I; response to activity; vascular endothelial growth factor receptor signaling pathway; response to progesterone stimulus; superoxide release; positive regulation of blood pressure; aging

Disease: Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-positive, Type Ii
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 Research Articles on NOX2    1. NCF2 in Asian populations shows a pattern of diversity characterized by a differentiated haplotype structure.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NOX2 elisa kitPathways associated with NOX2 elisa kit
 Reference Product  PubMed Publications
 CYBB elisa kit  >31 publications with NOX2 and CYBB
 NCF1 elisa kit  >25 publications with NOX2 and NCF1
 CYBA elisa kit  >21 publications with NOX2 and CYBA
 NCF4 elisa kit  >13 publications with NOX2 and NCF4
 RAC2 elisa kit  >4 publications with NOX2 and RAC2
 RAC1 elisa kit  >3 publications with NOX2 and RAC1
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing-Cross Presentation Pathway antibodies  Antigen Processing-Cross Presentation Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Cross-presentation Of Particulate Exogenous Antigens (phagosomes) Pathway antibodies  Cross-presentation Of Particulate Exogenous Antigens (phagosomes) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway antibodies  Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway Diagram
 Leishmaniasis Pathway antibodies  Leishmaniasis Pathway Diagram
 Leishmaniasis Pathway antibodies  Leishmaniasis Pathway Diagram
Diseases associated with NOX2 elisa kitOrgans/Tissues associated with NOX2 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >9 publications with NOX2 and Inflammation
 Neoplasms Antibodies  >7 publications with NOX2 and Neoplasms
 Necrosis Antibodies  >5 publications with NOX2 and Necrosis
 Cardiovascular Diseases Antibodies  >4 publications with NOX2 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >3 publications with NOX2 and Disease Models, Animal
 Lung Diseases Antibodies  >3 publications with NOX2 and Lung Diseases
 Hypertrophy Antibodies  >1 publications with NOX2 and Hypertrophy
 Fibrosis Antibodies  >1 publications with NOX2 and Fibrosis
 Heart Diseases Antibodies  >1 publications with NOX2 and Heart Diseases
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with NOX2 and Prenatal Exposure Delayed Effects
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >17 publications with NOX2 and Blood
 Lung Antibodies  >6 publications with NOX2 and Lung
 Lymph Antibodies  >3 publications with NOX2 and Lymph
 Brain Antibodies  >3 publications with NOX2 and Brain
 Lymph Node Antibodies  >3 publications with NOX2 and Lymph Node
 Bone Antibodies  >3 publications with NOX2 and Bone
 Skin Antibodies  >3 publications with NOX2 and Skin
 Bone Marrow Antibodies  >2 publications with NOX2 and Bone Marrow
 Spleen Antibodies  >2 publications with NOX2 and Spleen
 Kidney Antibodies  >2 publications with NOX2 and Kidney
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