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DDX41 elisa kit :: Rabbit Probable ATP-dependent RNA helicase DDX41 (DDX41) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7249330 DDX41 elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Probable ATP-dependent RNA helicase DDX41 (DDX41), ELISA Kit

 Also Known As   

Rabbit Probable ATP-dependent RNA helicase DDX41 (DDX41) ELISA Kit

 Product Gene Name   

DDX41 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    608170
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 Species Reactivity    Rabbit
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    2.5-50ng/mL
 Sensitivity    0.1ng/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of DDX41 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for DDX41 purchase    MBS7249330 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Probable ATP-dependent RNA helicase DDX41 (DDX41) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 2.5-50ng/mL in biological research samples containing DDX41, with an estimated sensitivity of 0.1ng/mL. The ELISA analytical biochemical technique of the MBS7249330 kit is based on DDX41 antibody-DDX41 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DDX41 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DDX41. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for DDX41 elisa kit    Epigenetics and Nuclear Signaling
NCBI/Uniprot data below describe general gene information for DDX41. It may not necessarily be applicable to this product.
 NCBI GI #    21071032
 NCBI GeneID    51428
 NCBI Accession #    NP_057306.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_016222.2 [Other Products]
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 UniProt Secondary Accession #    Q96BK6; Q96K05; Q9NT96; Q9NW04; B2RDC8 [Other Products]
 UniProt Related Accession #    Q9UJV9 [Other Products]
 Molecular Weight    69,838 Da [Similar Products]
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 NCBI Official Full Name    probable ATP-dependent RNA helicase DDX41
 NCBI Official Synonym Full Names    DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
 NCBI Official Symbol    DDX41 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    probable ATP-dependent RNA helicase DDX41; 2900024F02Rik; DEAD box protein 41; putative RNA helicase; DEAD-box protein abstrakt; DEAD box protein abstrakt homolog
 UniProt Protein Name    Probable ATP-dependent RNA helicase DDX41
 UniProt Synonym Protein Names   
DEAD box protein 41; DEAD box protein abstrakt homolog
 Protein Family    Probable ATP-dependent RNA helicase
 UniProt Gene Name    DDX41 [Similar Products]
 UniProt Synonym Gene Names    ABS [Similar Products]
 UniProt Entry Name    DDX41_HUMAN
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 NCBI Summary for DDX41    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene expression. [provided by RefSeq, Jul 2008]
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 UniProt Comments for DDX41    DDX41: Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved in pre-mRNA splicing. Belongs to the DEAD box helicase family. DDX41 subfamily.

Protein type: EC; RNA-binding; RNA splicing; Helicase; Spliceosome

Chromosomal Location of Human Ortholog: 5q35.3

Cellular Component: membrane; endoplasmic reticulum; cytosol

Molecular Function: protein binding; DNA binding; zinc ion binding; helicase activity; ATP binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA processing; regulation of interferon type I production; apoptosis; multicellular organismal development; positive regulation of interferon type I production; innate immune response; positive regulation of transcription from RNA polymerase II promoter; defense response to virus
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 Research Articles on DDX41    1. results suggest a mechanism whereby c-di-GMP and c-di-AMP are detected by DDX41, which forms a complex with STING to signal to TBK1-IRF3 and activate the interferon response
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with DDX41 elisa kitOrgans/Tissues associated with DDX41 elisa kit
 Products by Pathway  Pathway Diagram
 Cytosolic Sensors Of Pathogen-associated DNA Pathway antibodies  Cytosolic Sensors Of Pathogen-associated DNA Pathway Diagram
 IRF3-mediated Induction Of Type I IFN Pathway antibodies  IRF3-mediated Induction Of Type I IFN Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Regulation Of Innate Immune Responses To Cytosolic DNA Pathway antibodies  Regulation Of Innate Immune Responses To Cytosolic DNA Pathway Diagram
 STING Mediated Induction Of Host Immune Responses Pathway antibodies  STING Mediated Induction Of Host Immune Responses Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with DDX41 and Blood
 Bone Antibodies  >1 publications with DDX41 and Bone
 Bone Marrow Antibodies  >1 publications with DDX41 and Bone Marrow
 Prostate Antibodies  >1 publications with DDX41 and Prostate
 Liver Antibodies  >1 publications with DDX41 and Liver
 Kidney Antibodies  >1 publications with DDX41 and Kidney
 Lung Antibodies  >1 publications with DDX41 and Lung
 Stomach Antibodies  >1 publications with DDX41 and Stomach
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