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Renin elisa kit :: Rabbit Renin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS724409
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Renin, ELISA Kit

 Also Known As   

Rabbit Renin ELISA Kit

 Product Gene Name   

Renin elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 OMIM    613092
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 Species Reactivity    Rabbit
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact technical support.
 Other Notes    Small volumes of Renin elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Renin purchase    MBS724409 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Renin, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Renin. The ELISA analytical biochemical technique of the MBS724409 kit is based on Renin antibody-Renin antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Renin antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Renin. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for Renin elisa kit    Cardiovascular
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 Typical Testing Data/Standard Curve (for reference only) of Renin elisa kit    Renin elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS724409
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NCBI/Uniprot data below describe general gene information for Renin. It may not necessarily be applicable to this product.
 NCBI GI #    190994
 NCBI GeneID    5972
 NCBI Accession #    AAA60363.1 [Other Products]
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 UniProt Secondary Accession #    Q6FI38; Q6T5C2 [Other Products]
 UniProt Related Accession #    P00797 [Other Products]
 Molecular Weight    44,726 Da
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 NCBI Official Full Name    renin
 NCBI Official Synonym Full Names    renin
 NCBI Official Symbol    REN [Similar Products]
 NCBI Official Synonym Symbols   
HNFJ2
[Similar Products]
 NCBI Protein Information    renin; angiotensinogenase; renin precursor, renal; angiotensin-forming enzyme
 UniProt Protein Name    Renin
 UniProt Synonym Protein Names   
Angiotensinogenase
 Protein Family    Renin
 UniProt Gene Name    REN [Similar Products]
 UniProt Entry Name    RENI_HUMAN
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 NCBI Summary for Renin    Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]
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 UniProt Comments for Renin    REN: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Interacts with ATP6AP2. Interaction with ATP6AP2 results in a 5-fold increased efficiency in angiotensinogen processing. Belongs to the peptidase A1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; Protease; EC 3.4.23.15

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: extracellular space; cytoplasm; extracellular region; plasma membrane

Molecular Function: peptidase activity; insulin-like growth factor receptor binding; aspartic-type endopeptidase activity; receptor binding

Biological Process: response to cAMP; hormone-mediated signaling; male gonad development; cell maturation; renin-angiotensin regulation of aldosterone production; drinking behavior; response to lipopolysaccharide; proteolysis; angiotensin maturation; cellular protein metabolic process; regulation of blood pressure; regulation of MAPKKK cascade; beta-amyloid metabolic process; mesonephros development; kidney development

Disease: Renal Tubular Dysgenesis; Hyperuricemic Nephropathy, Familial Juvenile, 2
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 Research Articles on Renin    1. Data suggest that the renin-angiotensin system plays a critical role in placentation and nephrogenesis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Rabbit Renin ELISA Kit
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 MBS753660  Sheep Kynurenine ELISA Kit  MBS1410397  Recombinant Dictyostelium discoideum Kynurenine--oxoglutarate transaminase (ccbl)
 MBS6084490  3-Hydroxykynurenine-O-b-glucoside (rac-3OHKG)  MBS724409  Rabbit Renin ELISA Kit
 MBS1492101  Rabbit anti-human Renin receptor polyclonal Antibody, Biotin conjugated  MBS1352448  Recombinant Burkholderia pseudomallei Kynurenine formamidase (kynB)
 MBS9418505  Renin Antibody  MBS2005454  Polyclonal Antibody to Renin (REN)
 MBS2067599  APC-Linked Polyclonal Antibody to Oligophrenin 1 (OPHN1)  MBS1263664  Recombinant Legionella pneumophila Kynurenine 3-monooxygenase (kmo)
Products associated with Renin elisa kitPathways associated with Renin elisa kit
 Reference Product  PubMed Publications
 ACE elisa kit  >143 publications with Renin and ACE
 PTGS2 elisa kit  >74 publications with Renin and PTGS2
 AGT elisa kit  >56 publications with Renin and AGT
 INS elisa kit  >31 publications with Renin and INS
 NOS3 elisa kit  >23 publications with Renin and NOS3
 ATP6AP2 elisa kit  >4 publications with Renin and ATP6AP2
 RENBP elisa kit  >2 publications with Renin and RENBP
 DIF elisa kit  >1 publications with Renin and DIF
 EDN1 elisa kit  >1 publications with Renin and EDN1
 KNG1 elisa kit  >1 publications with Renin and KNG1
 Products by Pathway  Pathway Diagram
 ACE Inhibitor Pathway antibodies  ACE Inhibitor Pathway Diagram
 Metabolism Of Angiotensinogen To Angiotensins Pathway antibodies  Metabolism Of Angiotensinogen To Angiotensins Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
Diseases associated with Renin elisa kitOrgans/Tissues associated with Renin elisa kit
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >4277 publications with Renin and Kidney Diseases
 Renal Insufficiency Antibodies  >2902 publications with Renin and Renal Insufficiency
 Hypertension Antibodies  >1210 publications with Renin and Hypertension
 Heart Diseases Antibodies  >1093 publications with Renin and Heart Diseases
 Necrosis Antibodies  >888 publications with Renin and Necrosis
 Acute Kidney Injury Antibodies  >874 publications with Renin and Acute Kidney Injury
 Hypertension, Renal Antibodies  >613 publications with Renin and Hypertension, Renal
 Ischemia Antibodies  >596 publications with Renin and Ischemia
 Proteinuria Antibodies  >498 publications with Renin and Proteinuria
 Myocardial Ischemia Antibodies  >497 publications with Renin and Myocardial Ischemia
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >5456 publications with Renin and Kidney
 Lung Antibodies  >1047 publications with Renin and Lung
 Skin Antibodies  >515 publications with Renin and Skin
 Intestine Antibodies  >340 publications with Renin and Intestine
 Embryonic Tissue Antibodies  >227 publications with Renin and Embryonic Tissue
 Pancreas Antibodies  >139 publications with Renin and Pancreas
 Bladder Antibodies  >138 publications with Renin and Bladder
 Testis Antibodies  >125 publications with Renin and Testis
 Ovary Antibodies  >110 publications with Renin and Ovary
 Placenta Antibodies  >80 publications with Renin and Placenta
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