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TBP elisa kit :: Rabbit Tata Box Binding Protein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS031819 TBP elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tata Box Binding Protein (TBP), ELISA Kit

 Also Known As   

Rabbit Tata Box Binding Protein ELISA Kit

 Product Gene Name   

TBP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 6; NC_000006.11 (170863421..170881958). Location: 6q27
 OMIM    600075
 3D Structure    ModBase 3D Structure for P20226
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 Species Reactivity    Rabbit
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TBP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TBP purchase    MBS031819 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Tata Box Binding Protein (TBP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TBP. The ELISA analytical biochemical technique of the MBS031819 kit is based on TBP antibody-TBP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TBP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TBP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TBP. It may not necessarily be applicable to this product.
 NCBI GI #    82571689
 NCBI GeneID    6908
 NCBI Accession #    AAI10342.1 [Other Products]
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 UniProt Primary Accession #    P20226 [Other Products]
 UniProt Secondary Accession #    Q16845; Q6IBM6; Q9UC02; B4E3B3; F5H869 [Other Products]
 UniProt Related Accession #    P20226 [Other Products]
 Molecular Weight    37,698 Da
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 NCBI Official Full Name    TATA box binding protein
 NCBI Official Synonym Full Names    TATA box binding protein
 NCBI Official Symbol    TBP [Similar Products]
 NCBI Official Synonym Symbols   
HDL4; GTF2D; SCA17; TFIID; GTF2D1
[Similar Products]
 NCBI Protein Information    TATA-box-binding protein; TATA-box factor; TATA sequence-binding protein; TATA-box binding protein N-terminal domain; transcription initiation factor TFIID TBP subunit
 UniProt Protein Name    TATA-box-binding protein
 UniProt Synonym Protein Names   
TATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunit
 Protein Family    TATA-box-binding protein
 UniProt Gene Name    TBP [Similar Products]
 UniProt Synonym Gene Names    GTF2D1; TF2D; TFIID [Similar Products]
 UniProt Entry Name    TBP_HUMAN
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 NCBI Summary for TBP    Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010]
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 UniProt Comments for TBP    TBP: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre- initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Binds DNA as monomer. Belongs to the TFIID complex together with the TBP-associated factors (TAFs). Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B TAF1C and TAF1D. Association of TBP to form either TFIID or SL1/TIF-IB appears to be mutually exclusive. Interacts with TAF1A, TAF1B and TAF1C. Interacts with TFIIB, NCOA6, DRAP1, DR1 and ELF3. Interacts with SPIB, SNAPC1, SNAPC2 and SNAPC4. Interacts with UTF1. Interacts with BRF2. Interacts with UBTF. Interacts with GPBP1. Interacts with CITED2. Interacts with ATF7IP. Interacts with HIV-1 Tat. Widely expressed, with levels highest in the testis and ovary. Belongs to the TBP family.

Protein type: Nuclear receptor co-regulator; Transcription initiation complex; DNA-binding

Chromosomal Location of Human Ortholog: 6q27

Cellular Component: nucleoplasm; transcription factor TFIID complex; male pronucleus; cytoplasm; female pronucleus; transcription factor TFIIA complex

Molecular Function: protein binding; transcription factor binding; transcription factor activity

Biological Process: chromatin silencing at rDNA; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; viral reproduction; positive regulation of transcription, DNA-dependent; RNA elongation from RNA polymerase I promoter; transcription from RNA polymerase I promoter; termination of RNA polymerase I transcription; regulation of gene expression, epigenetic; transcription from RNA polymerase III promoter; negative regulation of gene expression, epigenetic; RNA elongation from RNA polymerase II promoter; spermatogenesis; gene expression; transcription initiation from RNA polymerase I promoter

Disease: Parkinson Disease, Late-onset; Spinocerebellar Ataxia 17
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 Research Articles on TBP    1. These studies suggest a model in which the distinct conformations of TFIID may serve as targets through which regulatory factors recruit TFIID to specific types of core promoters.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TBP elisa kitPathways associated with TBP elisa kit
 Reference Product  PubMed Publications
 TAF10 elisa kit  >22 publications with TBP and TAF10
 TAF7 elisa kit  >15 publications with TBP and TAF7
 TAF11 elisa kit  >10 publications with TBP and TAF11
 TAF8 elisa kit  >6 publications with TBP and TAF8
 TAF13 elisa kit  >3 publications with TBP and TAF13
 GTF2A2 elisa kit  >1 publications with TBP and GTF2A2
 GTF2A1 elisa kit  >1 publications with TBP and GTF2A1
 GTF2B elisa kit  >1 publications with TBP and GTF2B
 Products by Pathway  Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Eukaryotic Transcription Initiation Pathway antibodies  Eukaryotic Transcription Initiation Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram
 HIV Life Cycle Pathway antibodies  HIV Life Cycle Pathway Diagram
Diseases associated with TBP elisa kitOrgans/Tissues associated with TBP elisa kit
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >98 publications with TBP and Brain Diseases
 Death Antibodies  >46 publications with TBP and Death
 Necrosis Antibodies  >42 publications with TBP and Necrosis
 Immune System Diseases Antibodies  >41 publications with TBP and Immune System Diseases
 Disease Models, Animal Antibodies  >39 publications with TBP and Disease Models, Animal
 Liver Diseases Antibodies  >36 publications with TBP and Liver Diseases
 Lung Diseases Antibodies  >34 publications with TBP and Lung Diseases
 Atrophy Antibodies  >31 publications with TBP and Atrophy
 Adenocarcinoma Antibodies  >23 publications with TBP and Adenocarcinoma
 Inflammation Antibodies  >23 publications with TBP and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >278 publications with TBP and Blood
 Brain Antibodies  >96 publications with TBP and Brain
 Muscle Antibodies  >74 publications with TBP and Muscle
 Kidney Antibodies  >53 publications with TBP and Kidney
 Heart Antibodies  >49 publications with TBP and Heart
 Lung Antibodies  >43 publications with TBP and Lung
 Nerve Antibodies  >43 publications with TBP and Nerve
 Testis Antibodies  >42 publications with TBP and Testis
 Bone Antibodies  >39 publications with TBP and Bone
 Skin Antibodies  >34 publications with TBP and Skin
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