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TAFI elisa kit :: Rabbit Thrombin Activatable Fibrinolysis Inhibitor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS009981 TAFI elisa kit
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Thrombin Activatable Fibrinolysis Inhibitor (TAFI), ELISA Kit

 Also Known As   

Rabbit Thrombin Activatable Fibrinolysis Inhibitor ELISA Kit

 Product Gene Name   

TAFI elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 14; NC_000080.6 (75242287..75283555). Location: 14; 14 D2
 3D Structure    ModBase 3D Structure for Q9JHH6
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 Species Reactivity    Rabbit
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TAFI elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TAFI purchase    MBS009981 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Thrombin Activatable Fibrinolysis Inhibitor (TAFI) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TAFI. The ELISA analytical biochemical technique of the MBS009981 kit is based on TAFI antibody-TAFI antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TAFI antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TAFI. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TAFI. It may not necessarily be applicable to this product.
 NCBI GI #    7416967
 NCBI GeneID    56373
 NCBI Accession #    AAF62385.1 [Other Products]
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 UniProt Primary Accession #    Q9JHH6 [Other Products]
 UniProt Secondary Accession #    Q5EBI3; Q9QZF0 [Other Products]
 UniProt Related Accession #    Q9JHH6 [Other Products]
 Molecular Weight    48,871 Da
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 NCBI Official Full Name    thrombin-activatable fibrinolysis inhibitor
 NCBI Official Synonym Full Names    carboxypeptidase B2 (plasma)
 NCBI Official Symbol    Cpb2 [Similar Products]
 NCBI Official Synonym Symbols   
CPR; Cpu; TAFI; AI255929; 1110032P04Rik; 4930405E17Rik
[Similar Products]
 NCBI Protein Information    carboxypeptidase B2; carboxypeptidase R; carboxypeptidase U; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
 UniProt Protein Name    Carboxypeptidase B2
 UniProt Synonym Protein Names   
Carboxypeptidase R; CPR; Carboxypeptidase U; CPU; Thrombin-activable fibrinolysis inhibitor
 UniProt Gene Name    Cpb2 [Similar Products]
 UniProt Synonym Gene Names    Tafi; CPR; CPU; TAFI [Similar Products]
 UniProt Entry Name    CBPB2_MOUSE
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 UniProt Comments for TAFI    CPB2: Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. Belongs to the peptidase M14 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; Protease; EC 3.4.17.20

Cellular Component: extracellular space; extracellular region

Molecular Function: peptidase activity; hydrolase activity; zinc ion binding; metallopeptidase activity; carboxypeptidase activity; metal ion binding; metallocarboxypeptidase activity

Biological Process: fibrinolysis; negative regulation of fibrinolysis; response to heat; hemostasis; proteolysis; blood coagulation
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 Research Articles on TAFI    1. The unique NFkappaB site in the mouse CPB2 promoter is functional and mediates the upregulation of mouse CPB2 expression by TNFalpha.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with TAFI elisa kitDiseases associated with TAFI elisa kit
 Products by Pathway  Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Pancreatic Secretion Pathway antibodies  Pancreatic Secretion Pathway Diagram
 Pancreatic Secretion Pathway antibodies  Pancreatic Secretion Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >12 publications with TAFI and Necrosis
 Inflammation Antibodies  >8 publications with TAFI and Inflammation
 Vascular Diseases Antibodies  >7 publications with TAFI and Vascular Diseases
 Thrombosis Antibodies  >4 publications with TAFI and Thrombosis
 Carcinoma Antibodies  >3 publications with TAFI and Carcinoma
 Brain Diseases Antibodies  >3 publications with TAFI and Brain Diseases
 Liver Diseases Antibodies  >3 publications with TAFI and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with TAFI and Carcinoma, Hepatocellular
 Edema Antibodies  >2 publications with TAFI and Edema
 Hepatitis Antibodies  >2 publications with TAFI and Hepatitis
Organs/Tissues associated with TAFI elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >9 publications with TAFI and Liver
 Muscle Antibodies  >4 publications with TAFI and Muscle
 Lung Antibodies  >1 publications with TAFI and Lung
 Testis Antibodies  >1 publications with TAFI and Testis
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