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TNFRSF17 elisa kit :: Rabbit Tumor Necrosis Factor Receptor Superfamily, Member 17 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS055934 TNFRSF17 elisa kit
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17), ELISA Kit

 Also Known As   

Rabbit Tumor Necrosis Factor Receptor Superfamily, Member 17 ELISA Kit

 Product Gene Name   

TNFRSF17 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    275355
 3D Structure    ModBase 3D Structure for O14763
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 Species Reactivity    Rabbit
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TNFRSF17 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TNFRSF17 purchase    MBS055934 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TNFRSF17. The ELISA analytical biochemical technique of the MBS055934 kit is based on TNFRSF17 antibody-TNFRSF17 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TNFRSF17 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TNFRSF17. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TNFRSF17. It may not necessarily be applicable to this product.
 NCBI GI #    224494019
 NCBI GeneID    8795
 NCBI Accession #    NP_003833.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_003842.4 [Other Products]
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 UniProt Primary Accession #    O14763 [Other Products]
 UniProt Secondary Accession #    O14720; O15508; O15517; O15531; Q6UXM8; Q7Z360; Q9BVE0 [Other Products]
 UniProt Related Accession #    O14763 [Other Products]
 Molecular Weight    47,878 Da
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 NCBI Official Full Name    tumor necrosis factor receptor superfamily member 10B isoform 1
 NCBI Official Synonym Full Names    tumor necrosis factor receptor superfamily, member 10b
 NCBI Official Symbol    TNFRSF10B [Similar Products]
 NCBI Official Synonym Symbols   
DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5
[Similar Products]
 NCBI Protein Information    tumor necrosis factor receptor superfamily member 10B; Fas-like protein; death receptor 5; cytotoxic TRAIL receptor-2; TNF receptor superfamily member 10b; apoptosis inducing receptor TRAIL-R2; apoptosis inducing protein TRICK2A/2B; TNF-related apoptosis-inducing ligand receptor 2; death domain containing receptor for TRAIL/Apo-2L; tumor necrosis factor receptor-like protein ZTNFR9; p53-regulated DNA damage-inducible cell death receptor(killer)
 UniProt Protein Name    Tumor necrosis factor receptor superfamily member 10B
 UniProt Synonym Protein Names   
Death receptor 5; TNF-related apoptosis-inducing ligand receptor 2
 Protein Family    Tumor necrosis factor receptor superfamily
 UniProt Gene Name    TNFRSF10B [Similar Products]
 UniProt Synonym Gene Names    DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; TRAIL receptor 2; TRAIL-R2 [Similar Products]
 UniProt Entry Name    TR10B_HUMAN
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 NCBI Summary for TNFRSF17    The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
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 UniProt Comments for TNFRSF17    TRAIL-R2: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B. Homotrimer. Can interact with TRADD and RIPK1. Regulated by p53/TP53. Widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines such as HeLaS3, K-562, HL-60, SW480, A-549 and G-361; highly expressed in heart, peripheral blood lymphocytes, liver, pancreas, spleen, thymus, prostate, ovary, uterus, placenta, testis, esophagus, stomach and throughout the intestinal tract; not detectable in brain. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 8p22-p21

Cellular Component: integral to membrane; plasma membrane

Molecular Function: protein binding; TRAIL binding; receptor activity

Biological Process: regulation of apoptosis; caspase activation; cell surface receptor linked signal transduction; positive regulation of I-kappaB kinase/NF-kappaB cascade; induction of apoptosis via death domain receptors; apoptosis; activation of NF-kappaB-inducing kinase

Disease: Squamous Cell Carcinoma, Head And Neck
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 Research Articles on TNFRSF17    1. DR5 integrates opposing UPR signals to couple the endoplasmic reticulum stress and apoptotic cell fate.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TNFRSF17 elisa kitPathways associated with TNFRSF17 elisa kit
 Reference Product  PubMed Publications
 TNFSF10 elisa kit  >2722 publications with TNFRSF17 and TNFSF10
 CASP8 elisa kit  >782 publications with TNFRSF17 and CASP8
 FADD elisa kit  >413 publications with TNFRSF17 and FADD
 CFLAR elisa kit  >156 publications with TNFRSF17 and CFLAR
 TRADD elisa kit  >48 publications with TNFRSF17 and TRADD
 CASP10 elisa kit  >36 publications with TNFRSF17 and CASP10
 TP53 elisa kit  >29 publications with TNFRSF17 and TP53
 RIPK1 elisa kit  >21 publications with TNFRSF17 and RIPK1
 IKBKB elisa kit  >16 publications with TNFRSF17 and IKBKB
 IKBKG elisa kit  >1 publications with TNFRSF17 and IKBKG
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Modulation And Signaling Pathway antibodies  Apoptosis Modulation And Signaling Pathway Diagram
 Caspase-8 Activation By Cleavage Pathway antibodies  Caspase-8 Activation By Cleavage Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 DNA Damage Response Pathway antibodies  DNA Damage Response Pathway Diagram
 Death Receptor Signalling Pathway antibodies  Death Receptor Signalling Pathway Diagram
Diseases associated with TNFRSF17 elisa kitOrgans/Tissues associated with TNFRSF17 elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2041 publications with TNFRSF17 and Necrosis
 Neoplasms Antibodies  >1684 publications with TNFRSF17 and Neoplasms
 Leukemia Antibodies  >248 publications with TNFRSF17 and Leukemia
 Liver Diseases Antibodies  >163 publications with TNFRSF17 and Liver Diseases
 Breast Neoplasms Antibodies  >158 publications with TNFRSF17 and Breast Neoplasms
 Lung Neoplasms Antibodies  >151 publications with TNFRSF17 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >143 publications with TNFRSF17 and Neoplasms, Experimental
 Lung Diseases Antibodies  >141 publications with TNFRSF17 and Lung Diseases
 Colonic Neoplasms Antibodies  >139 publications with TNFRSF17 and Colonic Neoplasms
 Inflammation Antibodies  >133 publications with TNFRSF17 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >469 publications with TNFRSF17 and Blood
 Liver Antibodies  >218 publications with TNFRSF17 and Liver
 Lung Antibodies  >199 publications with TNFRSF17 and Lung
 Prostate Antibodies  >162 publications with TNFRSF17 and Prostate
 Brain Antibodies  >104 publications with TNFRSF17 and Brain
 Vascular Antibodies  >78 publications with TNFRSF17 and Vascular
 Kidney Antibodies  >75 publications with TNFRSF17 and Kidney
 Skin Antibodies  >65 publications with TNFRSF17 and Skin
 Bone Marrow Antibodies  >57 publications with TNFRSF17 and Bone Marrow
 Muscle Antibodies  >36 publications with TNFRSF17 and Muscle
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