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PON1 elisa kit :: Rabbit paraoxonase 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS928472
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $550 +1 FREE 8GB USB
96-Strip-Wells  /  $795 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,890 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,465 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

paraoxonase 1 (PON1), ELISA Kit

★Popular Item★
 Also Known As   

Rabbit paraoxonase 1, PON1 ELISA Kit

 Product Synonym Names    Rabbit paraoxonase 1 (PON1) ELISA kit; ESA; MVCD5; PON; arylesterase B-type; esterase A; paraoxonase B-type; serum aryldiakylphosphatase; paraoxonase 1
 Product Gene Name   

PON1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS928472 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for P27170
 Species Reactivity    Rabbit
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Rabbit PON1. No significant cross-reactivity or interference between Rabbit PON1 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, Cell lysates
 Detection Range    1.56 ng/ml-100 ng/ml
 Sensitivity    0.39 ng/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PON1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PON1 purchase    MBS928472 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the paraoxonase 1 (PON1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.56 ng/ml-100 ng/ml in biological research samples containing PON1, with an estimated sensitivity of 0.39 ng/ml. The ELISA analytical biochemical technique of the MBS928472 kit is based on PON1 antibody-PON1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PON1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PON1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, Cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Typical Testing Data/Standard Curve (for reference only) of PON1 elisa kit    PON1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS928472. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PON1. It may not necessarily be applicable to this product.
 NCBI GI #    126722853
 NCBI GeneID    100009133
 NCBI Accession #    NP_001075766.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001082297.1 [Other Products]
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 UniProt Primary Accession #    P27170 [Other Products]
 UniProt Secondary Accession #    Q9BGN1; Q9BGN2; Q9BGN3 [Other Products]
 UniProt Related Accession #    P27170 [Other Products]
 Molecular Weight    40,010 Da
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 NCBI Official Full Name    serum paraoxonase/arylesterase 1
 NCBI Official Symbol    PON1 [Similar Products]
 NCBI Official Synonym Symbols   
PON
[Similar Products]
 NCBI Protein Information    serum paraoxonase/arylesterase 1; PON 1; A-esterase 1; aromatic esterase 1; serum aryldialkylphosphatase 1
 UniProt Protein Name    Serum paraoxonase/arylesterase 1
 UniProt Synonym Protein Names   
Aromatic esterase 1; A-esterase 1; Serum aryldialkylphosphatase 1
 Protein Family    Serum paraoxonase/arylesterase
 UniProt Gene Name    PON1 [Similar Products]
 UniProt Synonym Gene Names    PON; PON 1; A-esterase 1 [Similar Products]
 UniProt Entry Name    PON1_RABIT
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 UniProt Comments for PON1    Function: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification.1 PublicationManual assertion based on experiment in:Ref.3

Catalytic activity: A phenyl acetate + H2O = a phenol + acetate.1 PublicationManual assertion based on experiment in:Ref.4

Cofactor: Binds 2 calcium ions per subunit
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 Research Articles on PON1    1. ApoE mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL paraoxonase activity
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with PON1 elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >493 publications with PON1 and Cardiovascular Diseases
 Vascular Diseases Antibodies  >422 publications with PON1 and Vascular Diseases
 Atherosclerosis Antibodies  >395 publications with PON1 and Atherosclerosis
 Coronary Artery Disease Antibodies  >236 publications with PON1 and Coronary Artery Disease
 Coronary Disease Antibodies  >235 publications with PON1 and Coronary Disease
 Myocardial Ischemia Antibodies  >216 publications with PON1 and Myocardial Ischemia
 Heart Diseases Antibodies  >198 publications with PON1 and Heart Diseases
 Nervous System Diseases Antibodies  >160 publications with PON1 and Nervous System Diseases
 Diabetes Mellitus Antibodies  >128 publications with PON1 and Diabetes Mellitus
 Brain Diseases Antibodies  >124 publications with PON1 and Brain Diseases
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