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sVEGFR-2 elisa kit :: Rabbit soluble vascular endothelial growth factor receptor 2 (sVEGFR-2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2601421
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $300 +1 FREE 8GB USB
96-Strip-Wells  /  $475 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
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 Product Name   

soluble vascular endothelial growth factor receptor 2 (sVEGFR-2), ELISA Kit

★Popular Item★
 Also Known As   

Rabbit soluble vascular endothelial growth factor receptor 2 (sVEGFR-2) ELISA Kit

 Product Gene Name   

sVEGFR-2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Species Reactivity    Rabbit
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 Specificity    No cross-reaction with other factors.
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 Samples    Rabbit serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant sVEGFR-2 concentration
 Assay Type    Sandwich
 Detection Range    20 ng/ml-0.312ng/ml
 Sensitivity    0.6ng/ml.
 Intra-assay Precision    <= 8%
 Inter-assay Precision    <= 12%
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of sVEGFR-2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for sVEGFR-2 purchase    MBS2601421 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the soluble vascular endothelial growth factor receptor 2 (sVEGFR-2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 20 ng/ml-0.312ng/ml in biological research samples containing sVEGFR-2, with an estimated sensitivity of 0.6ng/ml. The ELISA analytical biochemical technique of the MBS2601421 kit is based on sVEGFR-2 antibody-sVEGFR-2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect sVEGFR-2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, sVEGFR-2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Rabbit serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant sVEGFR-2 concentration. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for sVEGFR-2 elisa kit

  
Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Rabbit sVEGFR-2 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
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 Typical Testing Data/Standard Curve (for reference only) of sVEGFR-2 elisa kit    sVEGFR-2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2601421. Click to request current manual
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NCBI/Uniprot data below describe general gene information for sVEGFR-2. It may not necessarily be applicable to this product.
 NCBI GI #    215400616
 NCBI GeneID    16542
 NCBI Accession #    ACJ66293.1 [Other Products]
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 UniProt Secondary Accession #    C5H7S5 [Other Products]
 UniProt Related Accession #    P35918 [Other Products]
 Molecular Weight    75,230 Da
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 NCBI Official Full Name    soluble vascular endothelial growth factor receptor 2
 NCBI Official Synonym Full Names    kinase insert domain protein receptor
 NCBI Official Symbol    Kdr [Similar Products]
 NCBI Official Synonym Symbols   
Flk1; Ly73; Flk-1; Krd-1; VEGFR2; VEGFR-2; sVEGFR-2; 6130401C07
[Similar Products]
 NCBI Protein Information    vascular endothelial growth factor receptor 2; kinase NYK; VEGF receptor-2; fetal liver kinase 1; protein-tyrosine kinase receptor flk-1; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; vascular endothelial growth factor receptor- 2; soluble vascular endothelial growth factor receptor 2
 UniProt Protein Name    Vascular endothelial growth factor receptor 2
 UniProt Synonym Protein Names   
Fetal liver kinase 1; FLK-1; Kinase NYK; Protein-tyrosine kinase receptor flk-1; CD_antigen: CD309
 UniProt Gene Name    Kdr [Similar Products]
 UniProt Synonym Gene Names    Flk-1; Flk1; VEGFR-2; FLK-1 [Similar Products]
 UniProt Entry Name    VGFR2_MOUSE
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 UniProt Comments for sVEGFR-2    VEGFR2: a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2. Plays a key role in vascular development and regulation of vascular permeability.

Protein type: Protein kinase, TK; Kinase, protein; Protein kinase, tyrosine (receptor); Membrane protein, integral; EC 2.7.10.1; TK group; VEGFR family

Cellular Component: Golgi apparatus; neuron projection; cell surface; integral to plasma membrane; endoplasmic reticulum; early endosome; extracellular region; integral to membrane; cytosol; lipid raft; membrane; cell soma; cytoplasm; plasma membrane; cytoplasmic vesicle; nucleus; cell junction; endosome; external side of plasma membrane

Molecular Function: transferase activity; integrin binding; vascular endothelial growth factor receptor activity; protein binding; protein-tyrosine kinase activity; growth factor binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; transmembrane receptor protein tyrosine kinase activity; ATP binding; protein kinase activity

Biological Process: positive regulation of positive chemotaxis; multicellular organismal development; cell maturation; positive regulation of vasodilation; protein amino acid phosphorylation; positive regulation of long-term neuronal synaptic plasticity; calcium ion homeostasis; regulation of cell shape; elevation of cytosolic calcium ion concentration; positive regulation of mesenchymal cell proliferation; negative regulation of neuron apoptosis; positive regulation of TOR signaling pathway; response to drug; regulation of endothelial cell proliferation; cell fate commitment; embryonic hemopoiesis; regulation of endothelial cell differentiation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of angiogenesis; branching morphogenesis of a tube; cell migration during sprouting angiogenesis; positive regulation of endothelial cell proliferation; lymph vessel development; surfactant homeostasis; alveolus development; positive regulation of epithelial cell proliferation; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of nitric-oxide synthase biosynthetic process; negative regulation of apoptosis; peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation; positive regulation of calcium-mediated signaling; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of focal adhesion formation; positive regulation of MAPKKK cascade; ovarian follicle development; positive regulation of cell proliferation; hemopoiesis; angiogenesis; vasculogenesis; cell differentiation; positive regulation of BMP signaling pathway; endothelial cell differentiation; cell migration; male gonad development; response to hypoxia; positive regulation of protein amino acid phosphorylation; vascular endothelial growth factor receptor signaling pathway; phosphorylation; neurite morphogenesis; lung development; positive regulation of cell migration
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 Research Articles on sVEGFR-2    1. The osteostatin domain of C-terminal PTHrP phosphorylates VEGFR2 through Src activation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with sVEGFR-2 elisa kitOrgans/Tissues associated with sVEGFR-2 elisa kit
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EPH-Ephrin Signaling Pathway antibodies  EPH-Ephrin Signaling Pathway Diagram
 EPHA-mediated Growth Cone Collapse Pathway antibodies  EPHA-mediated Growth Cone Collapse Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >246 publications with sVEGFR-2 and Embryonic Tissue
 Bone Marrow Antibodies  >185 publications with sVEGFR-2 and Bone Marrow
 Lung Antibodies  >176 publications with sVEGFR-2 and Lung
 Brain Antibodies  >107 publications with sVEGFR-2 and Brain
 Kidney Antibodies  >94 publications with sVEGFR-2 and Kidney
 Eye Antibodies  >60 publications with sVEGFR-2 and Eye
 Skin Antibodies  >58 publications with sVEGFR-2 and Skin
 Ovary Antibodies  >38 publications with sVEGFR-2 and Ovary
 Intestine Antibodies  >20 publications with sVEGFR-2 and Intestine
 Adipose Tissue Antibodies  >18 publications with sVEGFR-2 and Adipose Tissue
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