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RDH5 elisa kit :: Rat 11-cis retinol dehydrogenase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2603881 RDH5 elisa kit
Unit / Price
48-Strip-Wells  /  $290 +1 FREE 8GB USB
96-Strip-Wells  /  $450 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,755 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,150 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

11-cis retinol dehydrogenase (RDH5), ELISA Kit

 Also Known As   

Rat 11-cis retinol dehydrogenase (RDH5) ELISA Kit

 Product Gene Name   

RDH5 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    136880
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 Species Reactivity    Rat
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of RDH5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RDH5 purchase    MBS2603881 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 11-cis retinol dehydrogenase (RDH5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RDH5. The ELISA analytical biochemical technique of the MBS2603881 kit is based on RDH5 antibody-RDH5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RDH5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RDH5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for RDH5. It may not necessarily be applicable to this product.
 NCBI GI #    1616654
 NCBI GeneID    5959
 NCBI Accession #    AAC50725.1 [Other Products]
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 UniProt Secondary Accession #    O00179; Q8TAI2 [Other Products]
 UniProt Related Accession #    Q92781 [Other Products]
 Molecular Weight    34,979 Da
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 NCBI Official Full Name    11-cis retinol dehydrogenase
 NCBI Official Synonym Full Names    retinol dehydrogenase 5
 NCBI Official Symbol    RDH5 [Similar Products]
 NCBI Official Synonym Symbols   
RDH1; 9cRDH; SDR9C5; HSD17B9
[Similar Products]
 NCBI Protein Information    11-cis retinol dehydrogenase
 UniProt Protein Name    11-cis retinol dehydrogenase
 UniProt Synonym Protein Names   
9-cis retinol dehydrogenase; 9cRDH; Retinol dehydrogenase 5; Short chain dehydrogenase/reductase family 9C member 5
 Protein Family    11-cis retinol dehydrogenase
 UniProt Gene Name    RDH5 [Similar Products]
 UniProt Synonym Gene Names    HSD17B9; RDH1; SDR9C5; 11-cis RDH; 11-cis RoDH; 9cRDH [Similar Products]
 UniProt Entry Name    RDH1_HUMAN
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 NCBI Summary for RDH5    This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene. [provided by RefSeq, Dec 2010]
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 UniProt Comments for RDH5    RDH5: Stereospecific 11-cis retinol dehydrogenase, which catalyzes the final step in the biosynthesis of 11-cis retinaldehyde, the universal chromophore of visual pigments. Also able to oxidize 9-cis-retinol and 13-cis-retinol, but not all- trans-retinol. Active in the presence of NAD as cofactor but not in the presence of NADP. Defects in RDH5 are a cause of retinitis punctata albescens (RPA); also known as fundus albipunctatus (FA). RPA is a rare form of stationary night blindness characterized by a delay in the regeneration of cone and rod photopigments. Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein type: Endoplasmic reticulum; Oxidoreductase; EC 1.1.1.315; Cofactor and Vitamin Metabolism - retinol

Chromosomal Location of Human Ortholog: 12q13-q14

Cellular Component: endoplasmic reticulum lumen; endoplasmic reticulum membrane

Molecular Function: retinol dehydrogenase activity

Biological Process: phototransduction, visible light; retinoid metabolic process; retinol metabolic process; visual perception

Disease: Fundus Albipunctatus
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 Research Articles on RDH5    1. A novel c.832C>T (p.Arg278Ter) nonsense mutation in RDH5 was identified. Preserved rod function was observed in one young subject in this study.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with RDH5 elisa kitPathways associated with RDH5 elisa kit
 Reference Product  PubMed Publications
 RLBP1 elisa kit  >8 publications with RDH5 and RLBP1
 RPE65 elisa kit  >5 publications with RDH5 and RPE65
 RDH10 elisa kit  >4 publications with RDH5 and RDH10
 LRAT elisa kit  >4 publications with RDH5 and LRAT
 RGR elisa kit  >2 publications with RDH5 and RGR
 Products by Pathway  Pathway Diagram
 RA Biosynthesis Pathway antibodies  RA Biosynthesis Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Retinoic Acid Pathway antibodies  Signaling By Retinoic Acid Pathway Diagram
 The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway antibodies  The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway Diagram
 Visual Phototransduction Pathway antibodies  Visual Phototransduction Pathway Diagram
 Visual Signal Transduction: Cones Pathway antibodies  Visual Signal Transduction: Cones Pathway Diagram
 Visual Signal Transduction: Rods Pathway antibodies  Visual Signal Transduction: Rods Pathway Diagram
 Vitamin A And Carotenoid Metabolism Pathway antibodies  Vitamin A And Carotenoid Metabolism Pathway Diagram
Diseases associated with RDH5 elisa kitOrgans/Tissues associated with RDH5 elisa kit
 Disease Name  Pubmed Publications
 Fundus Albipunctatus Antibodies  >40 publications with RDH5 and Fundus Albipunctatus
 Myopia Antibodies  >7 publications with RDH5 and Myopia
 Atrophy Antibodies  >3 publications with RDH5 and Atrophy
 Adenoma Antibodies  >2 publications with RDH5 and Adenoma
 Fatty Liver Antibodies  >1 publications with RDH5 and Fatty Liver
 Hypertrophy Antibodies  >1 publications with RDH5 and Hypertrophy
 Hyperplasia Antibodies  >1 publications with RDH5 and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >57 publications with RDH5 and Eye
 Liver Antibodies  >5 publications with RDH5 and Liver
 Kidney Antibodies  >4 publications with RDH5 and Kidney
 Intestine Antibodies  >3 publications with RDH5 and Intestine
 Bone Antibodies  >2 publications with RDH5 and Bone
 Spleen Antibodies  >1 publications with RDH5 and Spleen
 Stomach Antibodies  >1 publications with RDH5 and Stomach
 Testis Antibodies  >1 publications with RDH5 and Testis
 Uterus Antibodies  >1 publications with RDH5 and Uterus
 Mammary Gland Antibodies  >1 publications with RDH5 and Mammary Gland
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