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YWHAE elisa kit :: Rat 14-3-3 protein epsilon (YWHAE) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7236639 YWHAE elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

14-3-3 protein epsilon (YWHAE), ELISA Kit

 Also Known As   

Rat 14-3-3 protein epsilon (YWHAE) ELISA Kit

 Product Gene Name   

YWHAE elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    605066
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 Species Reactivity    Rat
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of YWHAE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for YWHAE purchase    MBS7236639 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 14-3-3 protein epsilon (YWHAE) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing YWHAE. The ELISA analytical biochemical technique of the MBS7236639 kit is based on YWHAE antibody-YWHAE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect YWHAE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, YWHAE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for YWHAE elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for YWHAE. It may not necessarily be applicable to this product.
 NCBI GI #    5803225
 NCBI GeneID    7531
 NCBI Accession #    NP_006752.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006761.4 [Other Products]
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 UniProt Secondary Accession #    P29360; P42655; Q4VJB6; Q53XZ5; Q63631; Q7M4R4; B3KY71; D3DTH5 [Other Products]
 UniProt Related Accession #    P62258 [Other Products]
 Molecular Weight    26,504 Da [Similar Products]
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 NCBI Official Full Name    14-3-3 protein epsilon
 NCBI Official Synonym Full Names    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
 NCBI Official Symbol    YWHAE [Similar Products]
 NCBI Official Synonym Symbols   
MDS; HEL2; MDCR; KCIP-1; 14-3-3E
[Similar Products]
 NCBI Protein Information    14-3-3 protein epsilon; 14-3-3 epsilon; epididymis luminal protein 2; protein kinase C inhibitor protein-1; mitochondrial import stimulation factor L subunit; tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
 UniProt Protein Name    14-3-3 protein epsilon
 Protein Family    14-3-3 protein
 UniProt Gene Name    YWHAE [Similar Products]
 UniProt Synonym Gene Names    14-3-3E [Similar Products]
 UniProt Entry Name    1433E_HUMAN
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 NCBI Summary for YWHAE    This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
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 UniProt Comments for YWHAE    14-3-3 epsilon: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: kinesin complex; focal adhesion; cytoplasmic vesicle membrane; mitochondrion; membrane; axon; melanosome; cytosol

Molecular Function: protein domain specific binding; protein binding; enzyme binding; potassium channel regulator activity; protein heterodimerization activity; histone deacetylase binding; phosphoprotein binding; phosphoserine binding

Biological Process: nerve growth factor receptor signaling pathway; viral reproduction; apoptosis; organelle organization and biogenesis; hippocampus development; neuron migration; regulation of caspase activity; regulation of the rate of heart contraction by hormone; substantia nigra development; mitotic cell cycle; cerebral cortex development; G2/M transition of mitotic cell cycle; protein targeting

Disease: Miller-dieker Lissencephaly Syndrome
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 Research Articles on YWHAE    1. data indicate that 14-3-3 is required for Bim expression and that it has an anti-cancer effect under pERK1/2 inhibition in 143B cells
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with YWHAE elisa kitPathways associated with YWHAE elisa kit
 Reference Product  PubMed Publications
 BAD elisa kit  >3 publications with YWHAE and BAD
 YWHAZ elisa kit  >3 publications with YWHAE and YWHAZ
 CDC25B elisa kit  >3 publications with YWHAE and CDC25B
 BRAF elisa kit  >1 publications with YWHAE and BRAF
 MAP2K1 elisa kit  >1 publications with YWHAE and MAP2K1
 RAF1 elisa kit  >1 publications with YWHAE and RAF1
 Products by Pathway  Pathway Diagram
 Activation Of BAD And Translocation To Mitochondria Pathway antibodies  Activation Of BAD And Translocation To Mitochondria Pathway Diagram
 Activation Of BH3-only Proteins Pathway antibodies  Activation Of BH3-only Proteins Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
Diseases associated with YWHAE elisa kitOrgans/Tissues associated with YWHAE elisa kit
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >8 publications with YWHAE and Brain Diseases
 Classical Lissencephalies and Subcortical Band Heterotopias Antibodies  >8 publications with YWHAE and Classical Lissencephalies and Subcortical Band Heterotopias
 Cardiovascular Diseases Antibodies  >5 publications with YWHAE and Cardiovascular Diseases
 Necrosis Antibodies  >5 publications with YWHAE and Necrosis
 Heart Diseases Antibodies  >4 publications with YWHAE and Heart Diseases
 Adenocarcinoma Antibodies  >4 publications with YWHAE and Adenocarcinoma
 Heart Defects, Congenital Antibodies  >4 publications with YWHAE and Heart Defects, Congenital
 Kidney Diseases Antibodies  >3 publications with YWHAE and Kidney Diseases
 Inflammation Antibodies  >3 publications with YWHAE and Inflammation
 Carcinoma, Hepatocellular Antibodies  >2 publications with YWHAE and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >23 publications with YWHAE and Brain
 Heart Antibodies  >8 publications with YWHAE and Heart
 Blood Antibodies  >6 publications with YWHAE and Blood
 Vascular Antibodies  >5 publications with YWHAE and Vascular
 Nerve Antibodies  >5 publications with YWHAE and Nerve
 Muscle Antibodies  >5 publications with YWHAE and Muscle
 Kidney Antibodies  >4 publications with YWHAE and Kidney
 Liver Antibodies  >3 publications with YWHAE and Liver
 Uterus Antibodies  >3 publications with YWHAE and Uterus
 Stomach Antibodies  >2 publications with YWHAE and Stomach
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