NP_036717.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
46,429 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 1A
NCBI Official Synonym Full Names
5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
NCBI Protein Information
5-hydroxytryptamine receptor 1A; 5-HT1A; 5-HT-1A; serotonin receptor 1A
UniProt Protein Name
5-hydroxytryptamine receptor 1A
UniProt Synonym Protein Names
Serotonin receptor 1A
UniProt Synonym Gene Names
UniProt Entry Name
5HT1A_RAT
NCBI Summary for HTR1A
regulates AMPA receptor channels in the prefrontal cortex; regulation is mediated via inhibition of Ca2+/calmodulin-dependent kinase II [RGD, Feb 2006]
UniProt Comments for HTR1A
5-HT(1A): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family. 5- hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.
Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: axon hillock; cell soma; membrane; integral to plasma membrane
Molecular Function: serotonin binding; protein binding; serotonin receptor activity; G-protein alpha-subunit binding; drug binding
Biological Process: cell proliferation; G-protein coupled receptor protein signaling pathway; vasoconstriction; positive regulation of microtubule depolymerization; behavioral fear response; serotonin receptor, adenylate cyclase inhibiting pathway; regulation of serotonin secretion; regulation of dopamine metabolic process; regulation of hormone secretion; serotonin metabolic process; serotonin receptor signaling pathway; regulation of behavior
Research Articles on HTR1A
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Pathways associated with HTR1A elisa kit
Diseases associated with HTR1A elisa kit
Organs/Tissues associated with HTR1A elisa kit
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