NP_444505.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,436 Da
NCBI Official Full Name
60S acidic ribosomal protein P0
NCBI Official Synonym Full Names
ribosomal protein, large, P0
NCBI Protein Information
60S acidic ribosomal protein P0; 60S ribosomal protein L10E; acidic ribosomal phosphoprotein P0
UniProt Protein Name
60S acidic ribosomal protein P0
UniProt Synonym Protein Names
60S ribosomal protein L10E
UniProt Entry Name
RLA0_HUMAN
NCBI Summary for RPLP0
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
UniProt Comments for RPLP0
RPLP0: a ribosomal protein of the L10P family. Located in the cytoplasm and nucleus. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This protein is a component of the 60S subunit.
Protein type: Ribosomal; Translation
Chromosomal Location of Human Ortholog: 12q24.2
Cellular Component: focal adhesion; membrane; cytoplasm; ribonucleoprotein complex; cytosol; nucleus
Molecular Function: protein binding; structural constituent of ribosome; RNA binding
Biological Process: SRP-dependent cotranslational protein targeting to membrane; translational elongation; cellular protein metabolic process; viral reproduction; translation; mRNA catabolic process, nonsense-mediated decay; ribosome biogenesis and assembly; translational initiation; gene expression; viral transcription; viral infectious cycle; translational termination
Research Articles on RPLP0
Precautions
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Products associated with RPLP0 elisa kit
Pathways associated with RPLP0 elisa kit
Diseases associated with RPLP0 elisa kit
Organs/Tissues associated with RPLP0 elisa kit
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