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AP4E1 elisa kit :: Rat AP-4 complex subunit epsilon-1 (AP4E1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7237543 AP4E1 elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AP-4 complex subunit epsilon-1 (AP4E1), ELISA Kit

 Also Known As   

Rat AP-4 complex subunit epsilon-1 (AP4E1) ELISA Kit

 Product Gene Name   

AP4E1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 613744
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 Species Reactivity    Rat
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    100-2500pg/mL
 Sensitivity    1.0pg/ml
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AP4E1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AP4E1 purchase    MBS7237543 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the AP-4 complex subunit epsilon-1 (AP4E1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 100-2500pg/mL in biological research samples containing AP4E1, with an estimated sensitivity of 1.0pg/ml. The ELISA analytical biochemical technique of the MBS7237543 kit is based on AP4E1 antibody-AP4E1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AP4E1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AP4E1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for AP4E1 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for AP4E1. It may not necessarily be applicable to this product.
 NCBI GI #    145559441
 NCBI GeneID    23431
 NCBI Accession #    Q9UPM8.2 [Other Products]
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 UniProt Secondary Accession #    Q68D31; Q9Y588; A0AVD6; A1L4A9; A6NNX7; H0YKX4 [Other Products]
 UniProt Related Accession #    Q9UPM8 [Other Products]
 Molecular Weight    119,482 Da
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 NCBI Official Full Name    AP-4 complex subunit epsilon-1
 NCBI Official Synonym Full Names    adaptor-related protein complex 4, epsilon 1 subunit
 NCBI Official Symbol    AP4E1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    AP-4 complex subunit epsilon-1; epsilon-adaptin; AP-4 adaptor complex subunit epsilon; adaptor-related protein complex AP-4 epsilon; adaptor-related protein complex 4 subunit epsilon-1
 UniProt Protein Name    AP-4 complex subunit epsilon-1
 UniProt Synonym Protein Names   
AP-4 adaptor complex subunit epsilon; Adaptor-related protein complex 4 subunit epsilon-1; Epsilon subunit of AP-4; Epsilon-adaptin
 Protein Family    AP-4 complex
 UniProt Gene Name    AP4E1 [Similar Products]
 UniProt Entry Name    AP4E1_HUMAN
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 NCBI Summary for AP4E1    This gene encodes a member of the adaptor complexes large subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is a large subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Disruption of this gene may be associated with cerebral palsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
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 UniProt Comments for AP4E1    AP4E1: Subunit of novel type of clathrin- or non-clathrin- associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. Defects in AP4E1 are the cause of cerebral palsy spastic quadriplegic type 4 (CPSQ4). A non-progressive disorder of movement and/or posture resulting from defects in the developing central nervous system. Affected individuals manifest motor and posture impairments often associated with epilepsy and disturbances of cognition, behavior, sensation, and communication. Belongs to the adaptor complexes large subunit family.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: Golgi apparatus; membrane coat; coated pit

Biological Process: vesicle-mediated transport; intracellular protein transport

Disease: Spastic Paraplegia 51, Autosomal Recessive
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 Research Articles on AP4E1    1. An autosomal recessive form of spastic tetraplegic cerebral palsy with profound intellectual disability, microcephaly, epilepsy and white matter loss in a consanguineous family resulting from a homozygous deletion involving AP4E1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AP4E1 elisa kitPathways associated with AP4E1 elisa kit
 Reference Product  PubMed Publications
 AP4B1 elisa kit  >4 publications with AP4E1 and AP4B1
 AP4M1 elisa kit  >4 publications with AP4E1 and AP4M1
 AP4S1 elisa kit  >4 publications with AP4E1 and AP4S1
 Products by Pathway  Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Trans-Golgi Network Vesicle Budding Pathway antibodies  Trans-Golgi Network Vesicle Budding Pathway Diagram
Diseases associated with AP4E1 elisa kitOrgans/Tissues associated with AP4E1 elisa kit
 Disease Name  Pubmed Publications
 Intellectual Disability Antibodies  >5 publications with AP4E1 and Intellectual Disability
 Congenital Abnormalities Antibodies  >2 publications with AP4E1 and Congenital Abnormalities
 Musculoskeletal Abnormalities Antibodies  >1 publications with AP4E1 and Musculoskeletal Abnormalities
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with AP4E1 and Brain
 Muscle Antibodies  >1 publications with AP4E1 and Muscle
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