P43245.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
141,387 Da
NCBI Official Full Name
Multidrug resistance protein 1
NCBI Official Synonym Full Names
ATP-binding cassette, subfamily B (MDR/TAP), member 1B
NCBI Protein Information
multidrug resistance protein 1; P-glycoprotein 1; P-glycoprotein/multidrug resistance 1; ATP-binding cassette sub-family B member 1; ATP-binding cassette, subfamily B, member 1B; ATP-binding cassette, sub-family B (MDR/TAP), member 1B; ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1)
UniProt Protein Name
Multidrug resistance protein 1
UniProt Synonym Protein Names
ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD_antigen: CD243
UniProt Synonym Gene Names
UniProt Entry Name
MDR1_RAT
NCBI Summary for ABCB1
member of the ATP-binding cassette (ABC) protein superfamily; may play a role in drug disposition [RGD, Feb 2006]
UniProt Comments for ABCB1
ABCB1B: Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
Protein type: Hydrolase; Membrane protein, integral; Transporter, ABC family; EC 3.6.3.44; Cell adhesion; Transporter
Cellular Component: Golgi membrane; intercellular canaliculus; membrane; mitochondrion; apical plasma membrane; integral to membrane
Molecular Function: protein binding; ATPase activity, coupled to transmembrane movement of substances; transporter activity; drug transporter activity; xenobiotic-transporting ATPase activity; ATP binding
Biological Process: response to drug; lactation; metabolic process; response to arsenic; response to organic cyclic substance; drug transport; transport; response to steroid hormone stimulus; response to hypoxia; multidrug transport; xenobiotic transport; establishment of blood-brain barrier; response to ionizing radiation; transmembrane transport; placenta development
Research Articles on ABCB1
Precautions
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Disclaimer
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Pathways associated with ABCB1 elisa kit
Organs/Tissues associated with ABCB1 elisa kit
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