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ACTalpha1 elisa kit :: Rat Actin Alpha 1, Skeletal Muscle ELISA Kit

Scan QR to view Datasheet Catalog #    MBS729138 ACTalpha1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Actin Alpha 1, Skeletal Muscle (ACTalpha1), ELISA Kit

 Also Known As   

Rat Actin Alpha 1, Skeletal Muscle ELISA Kit

 Product Gene Name   

ACTalpha1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    107280
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 Species Reactivity    Rat
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of ACTalpha1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ACTalpha1 purchase    MBS729138 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Actin Alpha 1, Skeletal Muscle (ACTalpha1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ACTalpha1. The ELISA analytical biochemical technique of the MBS729138 kit is based on ACTalpha1 antibody-ACTalpha1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ACTalpha1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ACTalpha1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for ACTalpha1 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for ACTalpha1. It may not necessarily be applicable to this product.
 NCBI GI #    50659080
 NCBI GeneID    12
 NCBI Accession #    NP_001076.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001085.4 [Other Products]
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 UniProt Secondary Accession #    Q13703; Q2TU87; Q2TU88; Q59GP9; Q6LBY8; Q6LDT7; Q6NSC9; Q8N177; Q96DW8; Q9UC47; B3KVQ7 [Other Products]
 UniProt Related Accession #    P01011 [Other Products]
 Molecular Weight    10,717 Da
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 NCBI Official Full Name    alpha-1-antichymotrypsin
 NCBI Official Synonym Full Names    serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
 NCBI Official Symbol    SERPINA3 [Similar Products]
 NCBI Official Synonym Symbols   
ACT; AACT; GIG24; GIG25
[Similar Products]
 NCBI Protein Information    alpha-1-antichymotrypsin; serpin A3; growth-inhibiting protein 24; growth-inhibiting protein 25; cell growth-inhibiting gene 24/25 protein; serine (or cysteine) proteinase inhibitor, clade A, member 3
 UniProt Protein Name    Alpha-1-antichymotrypsin
 UniProt Synonym Protein Names   
Cell growth-inhibiting gene 24/25 protein; Serpin A3Cleaved into the following chain:Alpha-1-antichymotrypsin His-Pro-less
 UniProt Gene Name    SERPINA3 [Similar Products]
 UniProt Synonym Gene Names    AACT; GIG24; GIG25; ACT [Similar Products]
 UniProt Entry Name    AACT_HUMAN
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 NCBI Summary for ACTalpha1    The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ACTalpha1    SERPINA3: Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. Belongs to the serpin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 14q32.1

Cellular Component: extracellular space; extracellular region; intracellular; nucleus

Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; DNA binding

Biological Process: regulation of lipid metabolic process; maintenance of gastrointestinal epithelium; acute-phase response; inflammatory response
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 Research Articles on ACTalpha1    1. ACT-17 variation presents a risk factor for Alzheimer's disease in the worldwide population, especially in the Caucasian population.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ACTalpha1 elisa kitDiseases associated with ACTalpha1 elisa kit
 Products by Pathway  Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >16 publications with ACTalpha1 and Inflammation
 Cardiovascular Diseases Antibodies  >14 publications with ACTalpha1 and Cardiovascular Diseases
 Mental Disorders Antibodies  >8 publications with ACTalpha1 and Mental Disorders
 Hypertension Antibodies  >4 publications with ACTalpha1 and Hypertension
 Liver Diseases Antibodies  >4 publications with ACTalpha1 and Liver Diseases
 Necrosis Antibodies  >4 publications with ACTalpha1 and Necrosis
 Heart Failure Antibodies  >1 publications with ACTalpha1 and Heart Failure
 Seizures Antibodies  >1 publications with ACTalpha1 and Seizures
 Acute Kidney Injury Antibodies  >1 publications with ACTalpha1 and Acute Kidney Injury
Organs/Tissues associated with ACTalpha1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >14 publications with ACTalpha1 and Blood
 Brain Antibodies  >10 publications with ACTalpha1 and Brain
 Liver Antibodies  >7 publications with ACTalpha1 and Liver
 Muscle Antibodies  >6 publications with ACTalpha1 and Muscle
 Uterus Antibodies  >4 publications with ACTalpha1 and Uterus
 Lung Antibodies  >3 publications with ACTalpha1 and Lung
 Placenta Antibodies  >3 publications with ACTalpha1 and Placenta
 Skin Antibodies  >2 publications with ACTalpha1 and Skin
 Eye Antibodies  >2 publications with ACTalpha1 and Eye
 Adrenal Gland Antibodies  >2 publications with ACTalpha1 and Adrenal Gland
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