AAD14378.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,976 Da
NCBI Official Full Name
adenosine A3 receptor, partial
NCBI Official Synonym Full Names
adenosine A3 receptor
NCBI Official Synonym Symbols
NCBI Protein Information
adenosine receptor A3
UniProt Protein Name
Adenosine receptor A3
UniProt Entry Name
AA3R_HUMAN
NCBI Summary for ADORA3
This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein. [provided by RefSeq, Nov 2014]
UniProt Comments for ADORA3
ADORA3: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1p13.2
Cellular Component: integral to membrane; plasma membrane
Molecular Function: adenosine receptor activity, G-protein coupled
Biological Process: adenosine receptor signaling pathway
Research Articles on ADORA3
Precautions
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Pathways associated with ADORA3 elisa kit
Diseases associated with ADORA3 elisa kit
Organs/Tissues associated with ADORA3 elisa kit
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