NP_062159.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
39,645 Da
NCBI Official Full Name
alcohol dehydrogenase 1
NCBI Official Synonym Full Names
alcohol dehydrogenase 1 (class I)
NCBI Protein Information
alcohol dehydrogenase 1
UniProt Protein Name
Alcohol dehydrogenase 1
UniProt Synonym Protein Names
Alcohol dehydrogenase A subunit
UniProt Synonym Gene Names
NCBI Summary for Adh1
alpha subunit of class I alcohol dehydrogenase; metabolizes a wide variety of substrates including ethanol, hydroxysteroids and lipid peroxidation products [RGD, Feb 2006]
UniProt Comments for Adh1
ADH1A: a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010]
Protein type: Amino Acid Metabolism - tyrosine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.1; Lipid Metabolism - fatty acid; Oxidoreductase; Transcription regulation; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450
Chromosomal Location of Human Ortholog: 2q44
Cellular Component: cytosol; intracellular; mitochondrion; nucleoplasm; plasma membrane
Molecular Function: alcohol dehydrogenase activity; alcohol dehydrogenase activity, zinc-dependent; drug binding; ethanol binding; NAD binding; protein homodimerization activity; retinol dehydrogenase activity
Biological Process: acetaldehyde biosynthetic process; behavioral response to ethanol; ethanol catabolic process; ethanol oxidation; organ regeneration; response to progesterone stimulus; response to retinoic acid; response to steroid hormone stimulus; response to testosterone stimulus; retinoic acid metabolic process; retinoid metabolic process; retinol metabolic process
Research Articles on Adh1
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Products associated with Adh1 elisa kit
Pathways associated with Adh1 elisa kit
Diseases associated with Adh1 elisa kit
Organs/Tissues associated with Adh1 elisa kit
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