NP_001134.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
21,730 Da
NCBI Official Full Name
amelogenin, Y isoform
NCBI Official Synonym Full Names
amelogenin, Y-linked
NCBI Official Synonym Symbols
NCBI Protein Information
amelogenin, Y isoform; amelogenin (Y chromosome)
UniProt Protein Name
Amelogenin, Y isoform
UniProt Synonym Gene Names
UniProt Entry Name
AMELY_HUMAN
NCBI Summary for AMELY
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in a related gene on chromosome X cause X-linked amelogenesis imperfecta. [provided by RefSeq, Jul 2008]
UniProt Comments for AMELY
AMELY: Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel. Belongs to the amelogenin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: Yp11.2
Cellular Component: extracellular matrix; proteinaceous extracellular matrix
Molecular Function: structural constituent of tooth enamel
Biological Process: biomineral formation
Research Articles on AMELY
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Products associated with AMELY elisa kit
Diseases associated with AMELY elisa kit
Organs/Tissues associated with AMELY elisa kit
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