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AR elisa kit :: Rat Androgen Receptor (AR) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2020398 (SPECIAL PROMOTION: Get FREE Starbucks gift card ($5 for 48-Wells-Kit or $10 for 96-Wells-Kit. Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells  /  $270 +1 FREE 8GB USB
48-Strip-Wells  /  $505 +1 FREE 8GB USB
96-Strip-Wells  /  $685 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,775 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,035 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Androgen Receptor (AR), ELISA Kit

★Popular Item★
 Also Known As   

Androgen Receptor (AR) ELISA Kit

 Product Synonym Names    AIS; DHTR; HUMARA; KD; NR3C4; SBMA; SMAX1; TFM; Dihydrotestosterone receptor; Nuclear Receptor Subfamily 3,Group C,Member 4; Testicular Feminization; Kennedy Disease
 Product Gene Name   

AR elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    300068
 3D Structure    ModBase 3D Structure for P10275
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 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Androgen Receptor (AR).
No significant cross-reactivity or interference between Androgen Receptor (AR) and analogues was observed.
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 Assay Type    Double-antibody Sandwich
 Samples    Tissue homogenates, Cell lysates, Cell culture supernates and Other Biological Fluids
 Detection Range    0.156-10ng/mL
 Sensitivity    < 0.062ng/mL
 Application    Enzyme-linked immunosorbent assay for Antigen Detection.
 Intra-assay Precision (Precision within an assay)    3 samples with low, middle and high level Androgen Receptor (AR) were tested 20 times on one plate, respectively.
 Inter-assay Precision (Precision between assays)    3 samples with low, middle and high level Androgen Receptor (AR) were tested on 3 different plates, 8 replicates in each plate.
 CV(%) =    SD/meanX100
 Intra-Assay    CV<10%
 Inter-Assay    CV<12%
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 Preparation and Storage    The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AR purchase    MBS2020398 is a ready-to-use microwell, strip plate Double-antibody Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Androgen Receptor (AR) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10ng/mL in biological research samples containing AR, with an estimated sensitivity of < 0.062ng/mL. The ELISA analytical biochemical technique of the MBS2020398 kit is based on AR antibody-AR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Tissue homogenates, Cell lysates, Cell culture supernates and Other Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for AR elisa kit

   The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Androgen Receptor (AR). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Androgen Receptor (AR). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Androgen Receptor (AR), biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Androgen Receptor (AR) in the samples is then determined by comparing the O.D. of the samples to the standard curve.
 Product Categories/Family for AR elisa kit    Reproductive science
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 Typical Testing Data/Standard Curve (for reference only) of AR elisa kit    AR elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2020398. Click to request current manual
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NCBI/Uniprot data below describe general gene information for AR. It may not necessarily be applicable to this product.
 NCBI GI #    178882
 NCBI GeneID    367
 NCBI Accession #    AAA51772.1 [Other Products]
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 UniProt Primary Accession #    P10275 [Other Products]
 UniProt Secondary Accession #    Q9UD95; A2RUN2; B1AKD7 [Other Products]
 UniProt Related Accession #    P10275 [Other Products]
 Molecular Weight    44,643 Da
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 NCBI Official Full Name    androgen receptor
 NCBI Official Synonym Full Names    androgen receptor
 NCBI Official Symbol    AR [Similar Products]
 NCBI Official Synonym Symbols   
KD; AIS; AR8; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA
[Similar Products]
 NCBI Protein Information    androgen receptor
 UniProt Protein Name    Androgen receptor
 UniProt Synonym Protein Names   
Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4
 Protein Family    Allatostatin
 UniProt Gene Name    AR [Similar Products]
 UniProt Synonym Gene Names    DHTR; NR3C4 [Similar Products]
 UniProt Entry Name    ANDR_HUMAN
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 NCBI Summary for AR    The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for AR    AR: a nuclear hormone receptor and transcription factor. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Two splice-variant isoforms have been described.

Protein type: DNA-binding; Nuclear receptor; Transcription factor

Chromosomal Location of Human Ortholog: Xq12

Cellular Component: nucleoplasm; protein complex; cytoplasm; nuclear chromatin; nucleus

Molecular Function: protein dimerization activity; protein binding; ligand-dependent nuclear receptor activity; androgen receptor activity; enzyme binding; DNA binding; androgen binding; zinc ion binding; beta-catenin binding; chromatin binding; transcription factor binding; transcription factor activity; receptor binding

Biological Process: prostate gland development; transcription initiation from RNA polymerase II promoter; intracellular receptor-mediated signaling pathway; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; signal transduction; protein oligomerization; activation of NF-kappaB transcription factor; negative regulation of integrin biosynthetic process; cell proliferation; cell-cell signaling; transport; androgen receptor signaling pathway; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase III promoter; steroid hormone mediated signaling; positive regulation of transcription from RNA polymerase II promoter; gene expression; positive regulation of integrin biosynthetic process; cell growth; sex differentiation; positive regulation of phosphorylation

Disease: Androgen Insensitivity Syndrome; Prostate Cancer; Hypospadias 1, X-linked; Androgen Insensitivity, Partial; Spinal And Bulbar Muscular Atrophy, X-linked 1
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 Research Articles on AR    1. CNVs of AR and CYP17A1 genes would appear to be associated with outcome of CRPC patients treated with abiraterone.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AR elisa kitPathways associated with AR elisa kit
 Reference Product  PubMed Publications
 CTNNB1 elisa kit  >677 publications with AR and CTNNB1
 SRC elisa kit  >675 publications with AR and SRC
 NCOA1 elisa kit  >62 publications with AR and NCOA1
 NCOA4 elisa kit  >56 publications with AR and NCOA4
 NCOA2 elisa kit  >51 publications with AR and NCOA2
 UBC elisa kit  >45 publications with AR and UBC
 NCOR1 elisa kit  >29 publications with AR and NCOR1
 KLK3 elisa kit  >29 publications with AR and KLK3
 NCOR2 elisa kit  >26 publications with AR and NCOR2
 NCOA3 elisa kit  >25 publications with AR and NCOA3
 Products by Pathway  Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Coregulation Of Androgen Receptor Activity Pathway antibodies  Coregulation Of Androgen Receptor Activity Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 IL-6 Signaling Pathway antibodies  IL-6 Signaling Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram
 Nongenotropic Androgen Signaling Pathway antibodies  Nongenotropic Androgen Signaling Pathway Diagram
Diseases associated with AR elisa kitOrgans/Tissues associated with AR elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >5385 publications with AR and Inflammation
 Heart Diseases Antibodies  >4202 publications with AR and Heart Diseases
 Genital Diseases, Male Antibodies  >3869 publications with AR and Genital Diseases, Male
 Necrosis Antibodies  >3352 publications with AR and Necrosis
 Prostatic Neoplasms Antibodies  >3057 publications with AR and Prostatic Neoplasms
 Kidney Diseases Antibodies  >1973 publications with AR and Kidney Diseases
 Hypertension Antibodies  >1454 publications with AR and Hypertension
 Breast Neoplasms Antibodies  >1323 publications with AR and Breast Neoplasms
 Liver Diseases Antibodies  >1304 publications with AR and Liver Diseases
 Hypertrophy Antibodies  >1236 publications with AR and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >16679 publications with AR and Bone
 Muscle Antibodies  >13091 publications with AR and Muscle
 Skin Antibodies  >9137 publications with AR and Skin
 Heart Antibodies  >6667 publications with AR and Heart
 Vascular Antibodies  >5623 publications with AR and Vascular
 Brain Antibodies  >5221 publications with AR and Brain
 Prostate Antibodies  >4615 publications with AR and Prostate
 Kidney Antibodies  >3710 publications with AR and Kidney
 Liver Antibodies  >3298 publications with AR and Liver
 Lung Antibodies  >2555 publications with AR and Lung
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