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Ang1-7 elisa kit :: Rat Angiotensin 1-7 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS702485
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Angiotensin 1-7 (Ang1-7), ELISA Kit

★Popular Item★
 Also Known As   

Rat angiotensin 1-7, Ang1-7 ELISA Kit

 Product Synonym Names    Rat angiotensin 1-7 (Ang1-7) ELISA kit; Angiotensin 1-7
 Product Gene Name   

Ang1-7 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS702485 Testing Data    Testing Data PDF
 OMIM    601667
 3D Structure    ModBase 3D Structure for Q15389
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 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of rat Ang1-7. No significant cross-reactivity or interference between rat Ang1-7 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Detection Range    18.75 pg/ml -1200 pg/mL
 Sensitivity    <4.68 pg/mL
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Ang1-7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Ang1-7 purchase    MBS702485 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Angiotensin 1-7 (Ang1-7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 18.75 pg/ml -1200 pg/mL in biological research samples containing Ang1-7, with an estimated sensitivity of <4.68 pg/mL. The ELISA analytical biochemical technique of the MBS702485 kit is based on Ang1-7 antibody-Ang1-7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Ang1-7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Ang1-7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for Ang1-7 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for Ang1-7 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any Ang1-7 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for Ang1-7 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of Ang1-7 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of Ang1-7 elisa kit    Ang1-7 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS702485. Click to request current manual
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NCBI/Uniprot data below describe general gene information for Ang1-7. It may not necessarily be applicable to this product.
 NCBI GI #    315434240
 NCBI GeneID    284
 NCBI Accession #    NP_001186788.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001199859.1 [Other Products]
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 UniProt Primary Accession #    Q15389 [Other Products]
 UniProt Secondary Accession #    Q5HYA0 [Other Products]
 UniProt Related Accession #    Q15389 [Other Products]
 Molecular Weight    57,456 Da
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 NCBI Official Full Name    angiopoietin-1 isoform 2
 NCBI Official Synonym Full Names    angiopoietin 1
 NCBI Official Symbol    ANGPT1 [Similar Products]
 NCBI Official Synonym Symbols   
AGP1; AGPT; ANG1
[Similar Products]
 NCBI Protein Information    angiopoietin-1; ANG-1
 UniProt Protein Name    Angiopoietin-1
 UniProt Gene Name    ANGPT1 [Similar Products]
 UniProt Synonym Gene Names    KIAA0003; ANG-1 [Similar Products]
 UniProt Entry Name    ANGP1_HUMAN
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 NCBI Summary for Ang1-7    Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010]
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 UniProt Comments for Ang1-7    Function: Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context. Inhibits angiogenesis and promotes vascular stability in quiescent vessels, where endothelial cells have tight contacts. In quiescent vessels, ANGPT1 oligomers recruit TEK to cell-cell contacts, forming complexes with TEK molecules from adjoining cells, and this leads to preferential activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascades. In migrating endothelial cells that lack cell-cell adhesions, ANGT1 recruits TEK to contacts with the extracellular matrix, leading to the formation of focal adhesion complexes, activation of PTK2/FAK and of the downstream kinases MAPK1/ERK2 and MAPK3/ERK1, and ultimately to the stimulation of sprouting angiogenesis. Mediates blood vessel maturation/stability. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme.4 PublicationsManual assertion based on experiment in:Ref.10
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 Research Articles on Ang1-7    1. Dengue virus reduces the expression of Ang1 and enhances the expression of Ang2 in endothelial cells, which may play a contributing role to the increased permeability of human primary endothelial cells during dengue virus infection.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Ang1-7 elisa kitPathways associated with Ang1-7 elisa kit
 Reference Product  PubMed Publications
 ANGPT2 elisa kit  >862 publications with Ang1-7 and ANGPT2
 VEGFA elisa kit  >127 publications with Ang1-7 and VEGFA
 TEK elisa kit  >76 publications with Ang1-7 and TEK
 MMP2 elisa kit  >9 publications with Ang1-7 and MMP2
 ETS1 elisa kit  >2 publications with Ang1-7 and ETS1
 PIK3CA elisa kit  >2 publications with Ang1-7 and PIK3CA
 PIK3CB elisa kit  >1 publications with Ang1-7 and PIK3CB
 PLG elisa kit  >1 publications with Ang1-7 and PLG
 Products by Pathway  Pathway Diagram
 Angiogenesis Pathway antibodies  Angiogenesis Pathway Diagram
 Angiopoietin Receptor Tie2-mediated Signaling Pathway antibodies  Angiopoietin Receptor Tie2-mediated Signaling Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 HIF-1 Signaling Pathway antibodies  HIF-1 Signaling Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Ras Signaling Pathway antibodies  Ras Signaling Pathway Diagram
Diseases associated with Ang1-7 elisa kitOrgans/Tissues associated with Ang1-7 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >199 publications with Ang1-7 and Inflammation
 Nervous System Diseases Antibodies  >131 publications with Ang1-7 and Nervous System Diseases
 Heart Diseases Antibodies  >124 publications with Ang1-7 and Heart Diseases
 Necrosis Antibodies  >109 publications with Ang1-7 and Necrosis
 Hypertension Antibodies  >99 publications with Ang1-7 and Hypertension
 Immune System Diseases Antibodies  >83 publications with Ang1-7 and Immune System Diseases
 Kidney Diseases Antibodies  >71 publications with Ang1-7 and Kidney Diseases
 Fibrosis Antibodies  >61 publications with Ang1-7 and Fibrosis
 Edema Antibodies  >60 publications with Ang1-7 and Edema
 Neoplasms, Experimental Antibodies  >57 publications with Ang1-7 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >1234 publications with Ang1-7 and Vascular
 Blood Antibodies  >853 publications with Ang1-7 and Blood
 Muscle Antibodies  >256 publications with Ang1-7 and Muscle
 Embryonic Tissue Antibodies  >194 publications with Ang1-7 and Embryonic Tissue
 Bone Antibodies  >158 publications with Ang1-7 and Bone
 Heart Antibodies  >151 publications with Ang1-7 and Heart
 Brain Antibodies  >131 publications with Ang1-7 and Brain
 Lung Antibodies  >122 publications with Ang1-7 and Lung
 Bone Marrow Antibodies  >108 publications with Ang1-7 and Bone Marrow
 Kidney Antibodies  >88 publications with Ang1-7 and Kidney
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