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ANTXR1 elisa kit :: Rat Anthrax Toxin Receptor 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS756343 ANTXR1 elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Anthrax Toxin Receptor 1 (ANTXR1), ELISA Kit

 Also Known As   

Rat Anthrax Toxin Receptor 1 ELISA Kit

 Product Gene Name   

ANTXR1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    606410
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 Species Reactivity    Rat
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    2.5-50ng/mL
 Sensitivity    0.1ng/ml
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ANTXR1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ANTXR1 purchase    MBS756343 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Anthrax Toxin Receptor 1 (ANTXR1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 2.5-50ng/mL in biological research samples containing ANTXR1, with an estimated sensitivity of 0.1ng/ml. The ELISA analytical biochemical technique of the MBS756343 kit is based on ANTXR1 antibody-ANTXR1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ANTXR1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ANTXR1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for ANTXR1 elisa kit    Immunology
NCBI/Uniprot data below describe general gene information for ANTXR1. It may not necessarily be applicable to this product.
 NCBI GI #    16933553
 NCBI GeneID    84168
 NCBI Accession #    NP_060623.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_018153.3 [Other Products]
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 UniProt Secondary Accession #    Q4ZFV6; Q53QD8; Q96P02; Q9NVP3; A8K7U8; J7K7G4; J7KF88 [Other Products]
 UniProt Related Accession #    Q9H6X2 [Other Products]
 Molecular Weight    39,742 Da
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 NCBI Official Full Name    anthrax toxin receptor 1 isoform 3
 NCBI Official Synonym Full Names    anthrax toxin receptor 1
 NCBI Official Symbol    ANTXR1 [Similar Products]
 NCBI Official Synonym Symbols   
ATR; GAPO; TEM8
[Similar Products]
 NCBI Protein Information    anthrax toxin receptor 1; 2310008J16Rik; 2810405N18Rik; tumor endothelial marker 8
 UniProt Protein Name    Anthrax toxin receptor 1
 UniProt Synonym Protein Names   
Tumor endothelial marker 8
 Protein Family    Anthrax toxin receptor
 UniProt Gene Name    ANTXR1 [Similar Products]
 UniProt Synonym Gene Names    ATR; TEM8 [Similar Products]
 UniProt Entry Name    ANTR1_HUMAN
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 NCBI Summary for ANTXR1    This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
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 UniProt Comments for ANTXR1    ANTXR1: Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI). HCI are benign, highly proliferative lesions involving aberrant localized growth of capillary endothelium. They are the most common tumor of infancy, occurring in up to 10% of all births. Hemangiomas tend to appear shortly after birth and show rapid neonatal growth for up to 12 months characterized by endothelial hypercellularity and increased numbers of mast cells. This phase is followed by slow involution at a rate of about 10% per year and replacement by fibrofatty stroma. Belongs to the ATR family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Actin-binding; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p13.1

Cellular Component: filopodium membrane; cell surface; plasma membrane; integral to membrane; endosome membrane

Molecular Function: actin filament binding; collagen binding; protein binding; transmembrane receptor activity; metal ion binding

Biological Process: actin cytoskeleton reorganization; reproductive process; pathogenesis; signal transduction

Disease: Gapo Syndrome; Hemangioma, Capillary Infantile
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 Research Articles on ANTXR1    1. ANTXR2 is expressed by human uterine smooth muscle cell and appears important for normal human uterine smooth muscle cell viability, migration and contractility.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ANTXR1 elisa kitPathways associated with ANTXR1 elisa kit
 Reference Product  PubMed Publications
 ANTXR2 elisa kit  >49 publications with ANTXR1 and ANTXR2
 LRP6 elisa kit  >6 publications with ANTXR1 and LRP6
 FURIN elisa kit  >1 publications with ANTXR1 and FURIN
 Products by Pathway  Pathway Diagram
 Cellular Roles Of Anthrax Toxin Pathway antibodies  Cellular Roles Of Anthrax Toxin Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Uptake And Actions Of Bacterial Toxins Pathway antibodies  Uptake And Actions Of Bacterial Toxins Pathway Diagram
 Uptake And Function Of Anthrax Toxins Pathway antibodies  Uptake And Function Of Anthrax Toxins Pathway Diagram
Diseases associated with ANTXR1 elisa kitOrgans/Tissues associated with ANTXR1 elisa kit
 Disease Name  Pubmed Publications
 Edema Antibodies  >23 publications with ANTXR1 and Edema
 Breast Neoplasms Antibodies  >9 publications with ANTXR1 and Breast Neoplasms
 Disease Models, Animal Antibodies  >5 publications with ANTXR1 and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >4 publications with ANTXR1 and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >4 publications with ANTXR1 and Lung Neoplasms
 Atrophy Antibodies  >3 publications with ANTXR1 and Atrophy
 Adenocarcinoma Antibodies  >3 publications with ANTXR1 and Adenocarcinoma
 Liver Diseases Antibodies  >3 publications with ANTXR1 and Liver Diseases
 Lung Diseases Antibodies  >3 publications with ANTXR1 and Lung Diseases
 Congenital Abnormalities Antibodies  >3 publications with ANTXR1 and Congenital Abnormalities
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >32 publications with ANTXR1 and Blood
 Vascular Antibodies  >21 publications with ANTXR1 and Vascular
 Lung Antibodies  >8 publications with ANTXR1 and Lung
 Ovary Antibodies  >5 publications with ANTXR1 and Ovary
 Skin Antibodies  >5 publications with ANTXR1 and Skin
 Muscle Antibodies  >4 publications with ANTXR1 and Muscle
 Embryonic Tissue Antibodies  >4 publications with ANTXR1 and Embryonic Tissue
 Connective Tissue Antibodies  >3 publications with ANTXR1 and Connective Tissue
 Liver Antibodies  >3 publications with ANTXR1 and Liver
 Uterus Antibodies  >3 publications with ANTXR1 and Uterus
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