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Alox12l elisa kit :: Rat Arachidonate 12-lipoxygenase, leukocyte-type (Alox12l/Alox12/Alox15) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9310691 Alox12l elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Arachidonate 12-lipoxygenase, leukocyte-type (Alox12l/Alox12/Alox15), ELISA Kit

★Popular Item★
 Also Known As   

Rat Arachidonate 12-lipoxygenase, leukocyte-type, Alox12l/Alox12/Alox15 ELISA Kit

 Product Synonym Names    Rat Arachidonate 12-lipoxygenase; leukocyte-type (Alox12l/Alox12/Alox15) ELISA kit; 12-LOX; 12S-LOX; LOG12; 12 (S) -lipoxygenase; platelet-type 12-lipoxygenase; Arachidonate 12-lipoxygenase; leukocyte-type (Alox12l/Alox12/Alox15)
 Product Gene Name   

Alox12l elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q02759
 Species Reactivity    Rat
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Alox12l elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Alox12l purchase    MBS9310691 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Arachidonate 12-lipoxygenase, leukocyte-type (Alox12l/Alox12/Alox15) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Alox12l. The ELISA analytical biochemical technique of the MBS9310691 kit is based on Alox12l antibody-Alox12l antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Alox12l antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Alox12l. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for Alox12l. It may not necessarily be applicable to this product.
 NCBI GI #    31542125
 NCBI GeneID    81639
 NCBI Accession #    NP_112272.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_031010.2 [Other Products]
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 UniProt Primary Accession #    Q02759 [Other Products]
 UniProt Secondary Accession #    F1MA51 [Other Products]
 UniProt Related Accession #    Q02759 [Other Products]
 Molecular Weight    75,378 Da
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 NCBI Official Full Name    arachidonate 15-lipoxygenase
 NCBI Official Synonym Full Names    arachidonate 15-lipoxygenase
 NCBI Official Symbol    Alox15 [Similar Products]
 NCBI Official Synonym Symbols   
12-LOX; 15-LOX; Alox12; Alox12l
[Similar Products]
 NCBI Protein Information    arachidonate 15-lipoxygenase; 12/15-LOX; 12/15-lipoxygenase; arachidonate omega-6 lipoxygenase; arachidonate 12-lipoxygenase, leukocyte-type
 UniProt Protein Name    Arachidonate 15-lipoxygenase
 UniProt Synonym Protein Names   
12/15-lipoxygenase; Arachidonate 12-lipoxygenase, leukocyte-type (EC:1.13.11.31); 12-LOX; Arachidonate omega-6 lipoxygenase
 UniProt Gene Name    Alox15 [Similar Products]
 UniProt Synonym Gene Names    Alox12l; 15-LOX; 12-LOX [Similar Products]
 UniProt Entry Name    LOX15_RAT
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 NCBI Summary for Alox12l    demonstrates 12-lipoxygenase and some 15-lipoxygenase enzyme activity [RGD, Feb 2006]
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 UniProt Comments for Alox12l    ALOX15: Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Belongs to the lipoxygenase family.

Protein type: Motility/polarity/chemotaxis; Lipid Metabolism - arachidonic acid; Oxidoreductase; EC 1.13.11.31; EC 1.13.11.33; Lipid Metabolism - linoleic acid

Cellular Component: extrinsic to internal side of plasma membrane; membrane; cytoplasm; plasma membrane; lipid particle; cytosol; sarcolemma

Molecular Function: hepoxilin A3 synthase activity; arachidonate 12-lipoxygenase activity; phosphatidylinositol-4,5-bisphosphate binding; arachidonate 15-lipoxygenase activity; hepoxilin-epoxide hydrolase activity; iron ion binding; potassium channel inhibitor activity

Biological Process: icosanoid biosynthetic process; ossification; positive regulation of heterotypic cell-cell adhesion; wound healing; phosphatidylethanolamine biosynthetic process; positive regulation of cell growth; bone mineralization; regulation of membrane potential; positive regulation of actin filament polymerization; lipoxygenase pathway; negative regulation of adaptive immune response; positive regulation of cell proliferation; arachidonic acid metabolic process; fatty acid oxidation; hepoxilin biosynthetic process; negative regulation of cell volume; apoptotic cell clearance; negative regulation of apoptosis
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 Research Articles on Alox12l    1. suggest that chronic hypoxia promotes monocyte infiltration into the vasculature and adhesion molecules upregulation in pulmonary arterial endothelium cells via a positive interaction between 15-LO/15-HETE and nuclear factor-kappaB
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Alox12l elisa kitPathways associated with Alox12l elisa kit
 Reference Product  PubMed Publications
 Ptgs2 elisa kit  >52 publications with Alox12l and Ptgs2
 Alox15b elisa kit  >50 publications with Alox12l and Alox15b
 Ptgs1 elisa kit  >27 publications with Alox12l and Ptgs1
 Pla2g4a elisa kit  >17 publications with Alox12l and Pla2g4a
 Pla2g6 elisa kit  >2 publications with Alox12l and Pla2g6
 Pla2g2d elisa kit  >1 publications with Alox12l and Pla2g2d
 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Eicosanoid Synthesis Pathway antibodies  Eicosanoid Synthesis Pathway Diagram
 Linoleic Acid Metabolism Pathway antibodies  Linoleic Acid Metabolism Pathway Diagram
 Linoleic Acid Metabolism Pathway antibodies  Linoleic Acid Metabolism Pathway Diagram
 Serotonergic Synapse Pathway antibodies  Serotonergic Synapse Pathway Diagram
Diseases associated with Alox12l elisa kitOrgans/Tissues associated with Alox12l elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >212 publications with Alox12l and Inflammation
 Atherosclerosis Antibodies  >138 publications with Alox12l and Atherosclerosis
 Disease Models, Animal Antibodies  >65 publications with Alox12l and Disease Models, Animal
 Hypertension Antibodies  >36 publications with Alox12l and Hypertension
 Necrosis Antibodies  >27 publications with Alox12l and Necrosis
 Kidney Diseases Antibodies  >23 publications with Alox12l and Kidney Diseases
 Heart Diseases Antibodies  >20 publications with Alox12l and Heart Diseases
 Fibrosis Antibodies  >16 publications with Alox12l and Fibrosis
 Arthritis, Rheumatoid Antibodies  >14 publications with Alox12l and Arthritis, Rheumatoid
 Pain Antibodies  >11 publications with Alox12l and Pain
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with Alox12l and Bone
 Connective Tissue Antibodies  >4 publications with Alox12l and Connective Tissue
 Heart Antibodies  >3 publications with Alox12l and Heart
 Muscle Antibodies  >3 publications with Alox12l and Muscle
 Brain Antibodies  >3 publications with Alox12l and Brain
 Vascular Antibodies  >2 publications with Alox12l and Vascular
 Embryonic Tissue Antibodies  >2 publications with Alox12l and Embryonic Tissue
 Ear Antibodies  >1 publications with Alox12l and Ear
 Kidney Antibodies  >1 publications with Alox12l and Kidney
 Umbilical Cord Antibodies  >1 publications with Alox12l and Umbilical Cord
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