NP_112272.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
75,378 Da
NCBI Official Full Name
arachidonate 15-lipoxygenase
NCBI Official Synonym Full Names
arachidonate 15-lipoxygenase
NCBI Official Synonym Symbols
12-LOX; 15-LOX; Alox12; Alox12l [Similar Products]
NCBI Protein Information
arachidonate 15-lipoxygenase; 12/15-LOX; 12/15-lipoxygenase; arachidonate omega-6 lipoxygenase; arachidonate 12-lipoxygenase, leukocyte-type
UniProt Protein Name
Arachidonate 15-lipoxygenase
UniProt Synonym Protein Names
12/15-lipoxygenase; Arachidonate 12-lipoxygenase, leukocyte-type (EC:1.13.11.31); 12-LOX; Arachidonate omega-6 lipoxygenase
UniProt Synonym Gene Names
UniProt Entry Name
LOX15_RAT
NCBI Summary for Alox12l
demonstrates 12-lipoxygenase and some 15-lipoxygenase enzyme activity [RGD, Feb 2006]
UniProt Comments for Alox12l
ALOX15: Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Belongs to the lipoxygenase family.
Protein type: Motility/polarity/chemotaxis; Lipid Metabolism - arachidonic acid; Oxidoreductase; EC 1.13.11.31; EC 1.13.11.33; Lipid Metabolism - linoleic acid
Cellular Component: extrinsic to internal side of plasma membrane; membrane; cytoplasm; plasma membrane; lipid particle; cytosol; sarcolemma
Molecular Function: hepoxilin A3 synthase activity; arachidonate 12-lipoxygenase activity; phosphatidylinositol-4,5-bisphosphate binding; arachidonate 15-lipoxygenase activity; hepoxilin-epoxide hydrolase activity; iron ion binding; potassium channel inhibitor activity
Biological Process: icosanoid biosynthetic process; ossification; positive regulation of heterotypic cell-cell adhesion; wound healing; phosphatidylethanolamine biosynthetic process; positive regulation of cell growth; bone mineralization; regulation of membrane potential; positive regulation of actin filament polymerization; lipoxygenase pathway; negative regulation of adaptive immune response; positive regulation of cell proliferation; arachidonic acid metabolic process; fatty acid oxidation; hepoxilin biosynthetic process; negative regulation of cell volume; apoptotic cell clearance; negative regulation of apoptosis
Research Articles on Alox12l
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Pathways associated with Alox12l elisa kit
Diseases associated with Alox12l elisa kit
Organs/Tissues associated with Alox12l elisa kit
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