NP_058689.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
26,622 Da
NCBI Official Full Name
apoptosis regulator Bcl-2
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 2
NCBI Official Synonym Symbols
NCBI Protein Information
apoptosis regulator Bcl-2; Bcl2-like protein; B-cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene
UniProt Protein Name
Apoptosis regulator Bcl-2
UniProt Synonym Gene Names
UniProt Entry Name
BCL2_RAT
NCBI Summary for BCL2
an anti-apoptotic protein; involved in inhibiting cell death in many different cell types [RGD, Feb 2006]
UniProt Comments for BCL2
Function: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Research Articles on BCL2
Precautions
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Disclaimer
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Products associated with BCL2 elisa kit
Pathways associated with BCL2 elisa kit
Diseases associated with BCL2 elisa kit
Disease Name |
Pubmed Publications |
Lymphoma, Non-Hodgkin Antibodies |
>712 publications with BCL2 and Lymphoma, Non-Hodgkin |
Carcinoma Antibodies |
>637 publications with BCL2 and Carcinoma |
Lymphoma, Follicular Antibodies |
>371 publications with BCL2 and Lymphoma, Follicular |
Necrosis Antibodies |
>360 publications with BCL2 and Necrosis |
Lymphoma, Large B-Cell, Diffuse Antibodies |
>353 publications with BCL2 and Lymphoma, Large B-Cell, Diffuse |
Breast Neoplasms Antibodies |
>302 publications with BCL2 and Breast Neoplasms |
Adenocarcinoma Antibodies |
>264 publications with BCL2 and Adenocarcinoma |
Disease Progression Antibodies |
>241 publications with BCL2 and Disease Progression |
Cell Transformation, Neoplastic Antibodies |
>144 publications with BCL2 and Cell Transformation, Neoplastic |
Leukemia, Lymphocytic, Chronic, B-Cell Antibodies |
>142 publications with BCL2 and Leukemia, Lymphocytic, Chronic, B-Cell |
Organs/Tissues associated with BCL2 elisa kit
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