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CTGF elisa kit :: Rat CTGF ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2513234
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CTGF, ELISA Kit

★Popular Item★
 Also Known As   

Rat CTGF (Connective Tissue Growth Factor) ELISA Kit

 Product Gene Name   

CTGF elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2513234 COA    COA PDF
 OMIM    121009
 3D Structure    ModBase 3D Structure for P29279
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 Species Reactivity    Rat
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 Specificity    This kit recognizes natural and recombinantRatCTGF. No significant cross-reactivity or interference between RatCTGF and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    31.25-2000pg/mL
 Sensitivity    Min: 18.75pg/mL; Max: 2000pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CTGF elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CTGF purchase    MBS2513234 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CTGF, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.25-2000pg/mL in biological research samples containing CTGF, with an estimated sensitivity of Min: 18.75pg/mL; Max: 2000pg/mL. The ELISA analytical biochemical technique of the MBS2513234 kit is based on CTGF antibody-CTGF antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CTGF antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CTGF. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CTGF elisa kit

   Intended Uses: This ELISA kit applies to the invitro quantitative determination of RatCTGFconcentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to CTGF. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for CTGFand Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain CTGF, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of CTGF.You can calculate the concentration of CTGFin the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of CTGF elisa kit    CTGF elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2513234. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CTGF. It may not necessarily be applicable to this product.
 NCBI GI #    4503123
 NCBI GeneID    1490
 NCBI Accession #    NP_001892.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001901.2 [Other Products]
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 UniProt Primary Accession #    P29279 [Other Products]
 UniProt Secondary Accession #    Q6LCY0; Q96A79; Q96QX2; Q9UDL6; E1P578 [Other Products]
 UniProt Related Accession #    P29279 [Other Products]
 Molecular Weight    35,205 Da
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 NCBI Official Full Name    connective tissue growth factor
 NCBI Official Synonym Full Names    connective tissue growth factor
 NCBI Official Symbol    CTGF [Similar Products]
 NCBI Official Synonym Symbols   
CCN2; NOV2; HCS24; IGFBP8
[Similar Products]
 NCBI Protein Information    connective tissue growth factor; CCN family member 2; IBP-8; IGF-binding protein 8; IGFBP-8; hypertrophic chondrocyte-specific protein 24; insulin-like growth factor-binding protein 8
 UniProt Protein Name    Connective tissue growth factor
 UniProt Synonym Protein Names   
CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8
 Protein Family    Connective tissue growth factor
 UniProt Gene Name    CTGF [Similar Products]
 UniProt Synonym Gene Names    CCN2; HCS24; IGFBP8; IBP-8; IGF-binding protein 8; IGFBP-8 [Similar Products]
 UniProt Entry Name    CTGF_HUMAN
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 NCBI Summary for CTGF    The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009]
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 UniProt Comments for CTGF    CTGF: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Belongs to the CCN family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; Cell adhesion

Chromosomal Location of Human Ortholog: 6q23.1

Cellular Component: Golgi apparatus; proteinaceous extracellular matrix; extracellular space; cis-Golgi network; intracellular membrane-bound organelle; perinuclear region of cytoplasm; plasma membrane; extracellular region; cell cortex; cytosol

Molecular Function: integrin binding; heparin binding; insulin-like growth factor binding; protein binding; growth factor activity; fibronectin binding

Biological Process: response to peptide hormone stimulus; epidermis development; response to anoxia; cell-matrix adhesion; positive regulation of collagen biosynthetic process; positive regulation of caspase activity; positive regulation of JNK cascade; cellular lipid metabolic process; response to estradiol stimulus; cell-cell signaling; positive regulation of cell proliferation; positive regulation of stress fiber formation; response to wounding; tissue homeostasis; response to glucose stimulus; regulation of cell growth; angiogenesis; cell adhesion; cell differentiation; cartilage condensation; positive regulation of cell activation; integrin-mediated signaling pathway; transcription initiation from RNA polymerase II promoter; cell migration; ossification; fibroblast growth factor receptor signaling pathway; organ senescence; response to mineralocorticoid stimulus; response to amino acid stimulus; gene expression; positive regulation of protein amino acid phosphorylation; regulation of chondrocyte differentiation; positive regulation of cell differentiation; lung development
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 Research Articles on CTGF    1. Reduced expression of CTGF promoted cell proliferation, migration, invasion and cell cycle progression through FAK/PI3K/AKT, epithelial-mesenchymal transition and MMP pathways in nasopharyngeal carcinoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CTGF elisa kitPathways associated with CTGF elisa kit
 Reference Product  PubMed Publications
 TGFB1 elisa kit  >663 publications with CTGF and TGFB1
 SMAD7 elisa kit  >58 publications with CTGF and SMAD7
 VEGFA elisa kit  >24 publications with CTGF and VEGFA
 BMP7 elisa kit  >18 publications with CTGF and BMP7
 BMP4 elisa kit  >14 publications with CTGF and BMP4
 FN1 elisa kit  >14 publications with CTGF and FN1
 TGFBR2 elisa kit  >13 publications with CTGF and TGFBR2
 WWTR1 elisa kit  >10 publications with CTGF and WWTR1
 TGFBI elisa kit  >4 publications with CTGF and TGFBI
 Products by Pathway  Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
 Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies  Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram
Diseases associated with CTGF elisa kitOrgans/Tissues associated with CTGF elisa kit
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >1238 publications with CTGF and Fibrosis
 Disease Models, Animal Antibodies  >392 publications with CTGF and Disease Models, Animal
 Kidney Diseases Antibodies  >353 publications with CTGF and Kidney Diseases
 Cardiovascular Diseases Antibodies  >291 publications with CTGF and Cardiovascular Diseases
 Inflammation Antibodies  >284 publications with CTGF and Inflammation
 Lung Diseases Antibodies  >187 publications with CTGF and Lung Diseases
 Heart Diseases Antibodies  >179 publications with CTGF and Heart Diseases
 Liver Diseases Antibodies  >176 publications with CTGF and Liver Diseases
 Carcinoma Antibodies  >154 publications with CTGF and Carcinoma
 Necrosis Antibodies  >150 publications with CTGF and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >2587 publications with CTGF and Connective Tissue
 Muscle Antibodies  >610 publications with CTGF and Muscle
 Kidney Antibodies  >597 publications with CTGF and Kidney
 Blood Antibodies  >493 publications with CTGF and Blood
 Vascular Antibodies  >451 publications with CTGF and Vascular
 Bone Antibodies  >293 publications with CTGF and Bone
 Lung Antibodies  >292 publications with CTGF and Lung
 Liver Antibodies  >286 publications with CTGF and Liver
 Heart Antibodies  >275 publications with CTGF and Heart
 Skin Antibodies  >220 publications with CTGF and Skin
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