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CTSD elisa kit :: Rat CTSD ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2508948
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CTSD, ELISA Kit

★Popular Item★
 Also Known As   

Rat CTSD (Cathepsin D) ELISA Kit

 Product Gene Name   

CTSD elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    116840
 3D Structure    ModBase 3D Structure for P07339
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 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Rat CTSD. No significant cross-reactivity or interference between Rat CTSD and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Rat CTSD and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    15.625-1000pg/mL
 Sensitivity    Min: 9.375pg/mL; Max: 1000pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CTSD elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CTSD purchase    MBS2508948 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CTSD, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.625-1000pg/mL in biological research samples containing CTSD, with an estimated sensitivity of Min: 9.375pg/mL; Max: 1000pg/mL. The ELISA analytical biochemical technique of the MBS2508948 kit is based on CTSD antibody-CTSD antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CTSD antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CTSD. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CTSD elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of CTSD in Rat serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat CTSD. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Rat CTSD and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat CTSD, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Rat CTSD. You can calculate the concentration of Rat CTSD in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of CTSD elisa kit    CTSD elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2508948. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CTSD. It may not necessarily be applicable to this product.
 NCBI GI #    48146011
 NCBI GeneID    1509
 NCBI Accession #    CAG33228.1 [Other Products]
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 UniProt Primary Accession #    P07339 [Other Products]
 UniProt Secondary Accession #    Q6IB57 [Other Products]
 UniProt Related Accession #    P07339 [Other Products]
 Molecular Weight    44,552 Da
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 NCBI Official Full Name    CTSD
 NCBI Official Synonym Full Names    cathepsin D
 NCBI Official Symbol    CTSD [Similar Products]
 NCBI Official Synonym Symbols   
CPSD; CLN10; HEL-S-130P
[Similar Products]
 NCBI Protein Information    cathepsin D; ceroid-lipofuscinosis, neuronal 10; epididymis secretory sperm binding protein Li 130P; lysosomal aspartyl peptidase; lysosomal aspartyl protease
 UniProt Protein Name    Cathepsin D
 Protein Family    Cathepsin
 UniProt Gene Name    CTSD [Similar Products]
 UniProt Synonym Gene Names    CPSD [Similar Products]
 UniProt Entry Name    CATD_HUMAN
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 NCBI Summary for CTSD    This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CTSD    CTSD: Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. Consists of a light chain and a heavy chain. Belongs to the peptidase A1 family.

Protein type: Motility/polarity/chemotaxis; Protease; Autophagy; EC 3.4.23.5

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: extracellular matrix; extracellular space; lysosomal lumen; lysosome; melanosome; extracellular region

Molecular Function: protein binding; aspartic-type endopeptidase activity

Biological Process: collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; antigen processing and presentation of exogenous peptide antigen via MHC class II; proteolysis

Disease: Ceroid Lipofuscinosis, Neuronal, 10
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 Research Articles on CTSD    1. CTSD, FKBP10, and SLC2A1 are novel genes that participate in the acquisition and maintenance of the adriamycin-resistant phenotype in leukemia cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CTSD elisa kitPathways associated with CTSD elisa kit
 Reference Product  PubMed Publications
 CTSB elisa kit  >29 publications with CTSD and CTSB
 TP53 elisa kit  >5 publications with CTSD and TP53
 CTSS elisa kit  >4 publications with CTSD and CTSS
 ESR1 elisa kit  >1 publications with CTSD and ESR1
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Ceramide Signaling Pathway antibodies  Ceramide Signaling Pathway Diagram
 Collagen Degradation Pathway antibodies  Collagen Degradation Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 LKB1 Signaling Events Pathway antibodies  LKB1 Signaling Events Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
Diseases associated with CTSD elisa kitOrgans/Tissues associated with CTSD elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >60 publications with CTSD and Nervous System Diseases
 Disease Models, Animal Antibodies  >22 publications with CTSD and Disease Models, Animal
 Inflammation Antibodies  >16 publications with CTSD and Inflammation
 Breast Neoplasms Antibodies  >14 publications with CTSD and Breast Neoplasms
 Liver Diseases Antibodies  >13 publications with CTSD and Liver Diseases
 Neoplasm Invasiveness Antibodies  >8 publications with CTSD and Neoplasm Invasiveness
 Necrosis Antibodies  >7 publications with CTSD and Necrosis
 Cardiovascular Diseases Antibodies  >7 publications with CTSD and Cardiovascular Diseases
 Fibrosis Antibodies  >6 publications with CTSD and Fibrosis
 Seizures Antibodies  >5 publications with CTSD and Seizures
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >41 publications with CTSD and Blood
 Brain Antibodies  >38 publications with CTSD and Brain
 Liver Antibodies  >22 publications with CTSD and Liver
 Muscle Antibodies  >19 publications with CTSD and Muscle
 Lung Antibodies  >14 publications with CTSD and Lung
 Kidney Antibodies  >12 publications with CTSD and Kidney
 Eye Antibodies  >9 publications with CTSD and Eye
 Vascular Antibodies  >9 publications with CTSD and Vascular
 Bone Antibodies  >8 publications with CTSD and Bone
 Skin Antibodies  >6 publications with CTSD and Skin
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