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CTDSP2 elisa kit :: Rat Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (CTDSP2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7214925 CTDSP2 elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (CTDSP2), ELISA Kit

 Also Known As   

Rat Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (CTDSP2) ELISA Kit

 Product Gene Name   

CTDSP2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    608711
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 Species Reactivity    Rat
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CTDSP2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CTDSP2 purchase    MBS7214925 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (CTDSP2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CTDSP2. The ELISA analytical biochemical technique of the MBS7214925 kit is based on CTDSP2 antibody-CTDSP2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CTDSP2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CTDSP2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for CTDSP2 elisa kit    Epigenetics and Nuclear Signaling
NCBI/Uniprot data below describe general gene information for CTDSP2. It may not necessarily be applicable to this product.
 NCBI GI #    93004102
 NCBI GeneID    10106
 NCBI Accession #    NP_005721.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_005730.3 [Other Products]
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 UniProt Secondary Accession #    Q53ZR2; Q6NZY3; Q9UEX1; A8K5H4 [Other Products]
 UniProt Related Accession #    O14595 [Other Products]
 Molecular Weight    30,664 Da
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 NCBI Official Full Name    carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2
 NCBI Official Synonym Full Names    CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
 NCBI Official Symbol    CTDSP2 [Similar Products]
 NCBI Official Synonym Symbols   
OS4; PSR2; SCP2
[Similar Products]
 NCBI Protein Information    carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; protein OS-4; small CTD phosphatase 2; NLI-interacting factor 2; small C-terminal domain phosphatase 2; conserved gene amplified in osteosarcoma; nuclear LIM interactor-interacting factor 2
 UniProt Protein Name    Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2
 UniProt Synonym Protein Names   
Nuclear LIM interactor-interacting factor 2; NLI-interacting factor 2; Protein OS-4; Small C-terminal domain phosphatase 2; Small CTD phosphatase 2; SCP2
 Protein Family    Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase
 UniProt Gene Name    CTDSP2 [Similar Products]
 UniProt Synonym Gene Names    NIF2; OS4; SCP2; NLI-interacting factor 2; SCP2 [Similar Products]
 UniProt Entry Name    CTDS2_HUMAN
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 UniProt Comments for CTDSP2    CTDSP2: Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.

Protein type: Nuclear receptor co-regulator; Phosphatase; EC 3.1.3.16

Chromosomal Location of Human Ortholog: 12q14.1

Cellular Component: nucleoplasm

Molecular Function: protein binding; metal ion binding; CTD phosphatase activity

Biological Process: cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; negative regulation of protein amino acid phosphorylation; unfolded protein response; protein amino acid dephosphorylation
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 Research Articles on CTDSP2    1. SCP2 acts as a phosphatase for regulatory phosphorylations in the linker region of Smad1 and Smad2
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CTDSP2 elisa kitPathways associated with CTDSP2 elisa kit
 Reference Product  PubMed Publications
 REST elisa kit  >2 publications with CTDSP2 and REST
 SMAD2 elisa kit  >1 publications with CTDSP2 and SMAD2
 Products by Pathway  Pathway Diagram
 BMP Receptor Signaling Pathway antibodies  BMP Receptor Signaling Pathway Diagram
 Coregulation Of Androgen Receptor Activity Pathway antibodies  Coregulation Of Androgen Receptor Activity Pathway Diagram
 IRE1alpha Activates Chaperones Pathway antibodies  IRE1alpha Activates Chaperones Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Regulation Of Cytoplasmic And Nuclear SMAD2/3 Signaling Pathway antibodies  Regulation Of Cytoplasmic And Nuclear SMAD2/3 Signaling Pathway Diagram
 Unfolded Protein Response (UPR) Pathway antibodies  Unfolded Protein Response (UPR) Pathway Diagram
 XBP1(S) Activates Chaperone Genes Pathway antibodies  XBP1(S) Activates Chaperone Genes Pathway Diagram
Diseases associated with CTDSP2 elisa kitOrgans/Tissues associated with CTDSP2 elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1 publications with CTDSP2 and Nervous System Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with CTDSP2 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with CTDSP2 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >2 publications with CTDSP2 and Bone
 Brain Antibodies  >2 publications with CTDSP2 and Brain
 Liver Antibodies  >1 publications with CTDSP2 and Liver
 Blood Antibodies  >1 publications with CTDSP2 and Blood
 Prostate Antibodies  >1 publications with CTDSP2 and Prostate
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